Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Oleanolic acid	IC50	11800.0 [1], 22310.0 [2], 40000.0 [3], 120000.0 [4]
	4-Bromo-3-(carboxymethoxy)-5-[4-[[oxo(3-pyridinyl)methyl]amino]phenyl]-2-thiophenecarboxylic acid	IC50	320000.0 [1]
	4-Bromo-3-(carboxymethoxy)-5-[4-[[oxo(3-pyridinyl)methyl]amino]phenyl]-2-thiophenecarboxylic acid	Ki	320000.0 [1]
	4-Bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid	Ki	500000.0 [1], 1000000.0 [2]
	Ursolic acid	IC50	3800.0 [1], 40000.0 [2]
	2-(Oxalyl-amino)-benzoic acid	Ki	2000000.0 [1]
	5-Iodo-2-(oxaloamino)benzoic acid	Ki	420000.0 [1]
	6-(Oxalyl-amino)-1H-indole-5-carboxylic acid	Ki	450000.0 [1], 550000.0 [2]
	2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-C]pyran-3-carboxylic acid	Ki	360000.0 [1]
	2-(Carboxyformamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid	Ki	410000.0 [1]
	1H-Indole-7-carboxylic acid, 6-[(carboxycarbonyl)amino]-	Ki	450000.0 [1], 550000.0 [2]
	2-(Carboxyformamido)thiophene-3-carboxylic acid	Ki	2000000.0 [1]
	3-(Carboxyformamido)thiophene-2-carboxylic acid	Ki	2000000.0 [1]
	2-[4-[[3,5-Bis[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	41000.0 [1]
	4-Bromo-5-[4-[(2-carboxyacetyl)amino]phenyl]-3-(carboxymethoxy)thiophene-2-carboxylic acid	Ki	1000000.0 [1]
	4-Bromo-3-(carboxymethoxy)-5-[3-[(3,3,5,5-tetramethylcyclohexyl)amino]phenyl]thiophene-2-carboxylic acid	Ki	1000000.0 [1]
	4-[5-(4-Benzyloxybenzylidene)-2,4-dioxothiazolidin-3-yl]methylbenzoic acid	IC50	27000.0 [1]
	4-Bromo-3-(carboxymethoxy)-5-[4-(dimethylamino)phenyl]thiophene-2-carboxylic acid	Ki	1000000.0 [1]
	Azane;[4-[4-ethoxy-2,2-bis(methoxycarbonyl)-4-oxobutyl]phenyl]sulfamic acid	IC50	288000.0 [1], 500000.0 [2]
	Azane;[4-[2,2-bis(methoxycarbonyl)-5-phenylpentyl]phenyl]sulfamic acid	IC50	409000.0 [1], 500000.0 [2]
	Azane;[4-[2-ethoxycarbonyl-3-methoxy-3-oxo-2-(phenylmethoxycarbonylamino)propyl]phenyl]sulfamic acid	IC50	227000.0 [1], 472000.0 [2]
	Maslinic acid	IC50	40000.0 [1]
	Cryptotanshinone	IC50	36900.0 [1]
	Corosolic acid	IC50	40000.0 [1]
	Moronic acid	IC50	45600.0 [1]
	4-Hydroxyphenylglyoxylic acid	IC50	2300000.0 [1]
	Morolic acid	IC50	35900.0 [1]
	2-(Oxalyl-amino)-4,5,6,7-tetrahydro-thieno[2,3-C]pyridine-3-carboxylic acid	Ki	2000000.0 [1]
	(4As,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(3-carboxy-3-methylbutanoyl)oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid	IC50	40000.0 [1]
	3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diol	IC50	50000.0 [1]
	Cefsulodin sodium salt	IC50	200000.0 [1]
	6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acid	IC50	50000.0 [1]
	Illudalic acid	IC50	1300.0 [1]
	1-Oxobenzo[f]chromene-2-carbaldehyde	IC50	1000000.0 [1]
	4-[4-(2,4-Dihydroxy-6-propylbenzoyl)oxy-2-hydroxy-6-propylbenzoyl]oxy-2-hydroxy-6-propylbenzoic acid	IC50	20000.0 [1]
	2-[4-[[4-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	250000.0 [1]
	Benzoic acid, 2-[(carboxycarbonyl)amino]-3-methyl-	Ki	2000000.0 [1]
	2-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxo-2-(prop-2-enoxycarbonylamino)propyl]-N-oxaloanilino]benzoic acid	Ki	96000.0 [1]
	3-(Carboxyformamido)-5-(thiophen-3-yl)thiophene-2-carboxylic acid	Ki	90000.0 [1]
	3-(Carboxyformamido)-5-phenylthiophene-2-carboxylic acid	Ki	90000.0 [1]
	2-(Carboxyformamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid	Ki	400000.0 [1]
	3-(Carboxyformamido)isonicotinic acid	Ki	2000000.0 [1]
	Benzoic acid, 2-[(carboxycarbonyl)methylamino]-	Ki	2000000.0 [1]
	3-(Carboxyformamido)-5-(4-(carboxymethoxy)phenyl)thiophene-2-carboxylic acid	Ki	50000.0 [1]
	Benzoic acid, 2-[(carboxycarbonyl)amino]-6-methyl-	Ki	2000000.0 [1]
	3-(Carboxyformamido)-4-methylthiophene-2-carboxylic acid	Ki	2000000.0 [1]
	5-[3-[(1-Benzylsulfonylpiperidin-4-yl)amino]phenyl]-4-bromo-3-(carboxymethoxy)thiophene-2-carboxylic acid	Ki	500000.0 [1]
	3-(Carboxyformamido)-5-(4-chlorophenyl)thiophene-2-carboxylic acid	Ki	160000.0 [1]
	(1R,2R,11R,14R,15S,18S,23S)-2,10,10,14,15,21,21-Heptamethyl-5,8-diazahexacyclo[12.12.0.02,11.04,9.015,24.018,23]hexacosa-4,6,8,24-tetraene-18-carboxylic acid	IC50	40000.0 [1]
	(1R,2R,15R,18R,19S,22S,27S)-2,14,14,18,19,25,25-Heptamethyl-5,12-diazaheptacyclo[16.12.0.02,15.04,13.06,11.019,28.022,27]triaconta-4,6,8,10,12,28-hexaene-22-carboxylic acid	IC50	40000.0 [1]
	2-(Carboxyformamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid	Ki	900000.0 [1]
	2-[[4-[2-Acetamido-3-oxo-3-(pentylamino)propyl]naphthalen-1-yl]-oxaloamino]benzoic acid	Ki	29600.0 [1]
	4-(Carboxyformamido)biphenyl-3-carboxylic acid	Ki	700000.0 [1]
	3-(Carboxyformamido)-5-(4-isobutylphenyl)thiophene-2-carboxylic acid	Ki	50000.0 [1]
	3-(Carboxyformamido)-5-(4-fluorophenyl)thiophene-2-carboxylic acid	Ki	110000.0 [1]
	3-(Carboxyformamido)-5-(3-nitrophenyl)thiophene-2-carboxylic acid	Ki	165000.0 [1]
	(2S)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-3-phenyl-propionic acid	IC50	3250.0 [1]
	5-(3-Aminophenyl)-3-(carboxyformamido)thiophene-2-carboxylic acid	Ki	113000.0 [1]
	4-Phenyl-[1,2]naphthoquinone	IC50	2490.0 [1]
	[[17-(Diphosphonomethyl)-26,28-dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9(27),10,12,15(26),16,18,21,23-dodecaenyl]-phosphonomethyl]phosphonic acid	IC50	100000.0 [1]
	[(26,28-Dihydroxy-25,27-dipropoxy-5-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaenyl)-phosphonomethyl]phosphonic acid	IC50	100000.0 [1]
	4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]aniline	IC50	120000.0 [1]
	4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]aniline	IC50	120000.0 [1]
	5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-(4-methylphenyl)benzamide	IC50	6950.0 [1]
	N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide	IC50	50000.0 [1]
	2,4-Dihydroxy-6-propylbenzoic acid	IC50	20000.0 [1]
	Isochroman mono-carboxylic acid	IC50	1941.0 [1]
	3-[5-[[2-Acetamido-3-[4-(2-carboxy-N-oxaloanilino)naphthalen-1-yl]propanoyl]amino]pentoxy]naphthalene-2-carboxylic acid	Ki	1300.0 [1]
	(5Z)-5-[[2-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-5-bromophenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	100000.0 [1]
	(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-20-phenyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acid	IC50	40000.0 [1]
	(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acid	IC50	40000.0 [1]
	2-[[4-[4-(3-Chloro-4-fluorophenyl)phenyl]-3-ethoxycarbonylthiophen-2-yl]carbamoyl]benzoic acid	IC50	100000.0 [1]
	8-[2-[4-[(E)-2-Carboxyethenyl]phenyl]-1,3-thiazol-4-yl]dibenzofuran-4-carboxylic acid	IC50	1981.0 [1]
	[3-[3-[(3S)-3-(Methylcarbamoyl)-7-(sulfoamino)-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropyl]phenyl]sulfamic acid	IC50	500000.0 [1]
	6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	10000.0 [1]
	3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	10000.0 [1]
	6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	10000.0 [1]
	[[3-(3-Cyclohexyl-2-hydroxyphenyl)phenyl]-difluoromethyl]phosphonic acid	Ki	900000.0 [1]
	[(S)-[4-[3-[(R)-(3,4-Dichlorophenyl)-hydroxymethyl]phenyl]phenyl]-hydroxymethyl]phosphonic acid	Ki	360000.0 [1]
	[(S)-[4-[3-[(S)-(3,4-Dichlorophenyl)-hydroxymethyl]phenyl]phenyl]-hydroxymethyl]phosphonic acid	Ki	390000.0 [1]
	2-[4-(Methylthio)-2-pyridinylmethylsulfinyl]-5-isopropoxy-1H-benzimidazole	IC50	18200.0 [1]
	2-(Oxaloamino)-6-(2-phenylethyl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acid	Ki	2100000.0 [1]
	(2R)-2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzofuran-11-yl)phenoxy]-3-phenylpropanoic acid	IC50	420.0 [1]
	2-[4-[2-Acetamido-3-[4-(5-chloro-3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxopropyl]-2-ethyl-N-oxaloanilino]benzoic acid	Ki	3000.0 [1]
	6-Biphenyl-4-yl-4-oxo-4H-chromene-3-carbaldehyde	IC50	1000000.0 [1]
	2-[4-[[3-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	120000.0 [1]
	3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine	IC50	12000.0 [1]
	3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine	IC50	28000.0 [1]
	2-(1-Carboxyethoxy)-5-[(2S)-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-oxopropyl]benzoic acid	Ki	30000.0 [1]
	2-[4-[[2-[(4-Oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	120000.0 [1]
	4-Cyclohexyl-1,2-naphthoquinone	IC50	8990.0 [1]
	2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzothiol-11-yl)phenoxy]acetic acid	IC50	1500.0 [1]
	2-(4-(7-(4-Methoxybenzoyl)cyclopenta[d][1,2]oxazin-4-yl)phenoxy)acetic acid	IC50	61700.0 [1]
	Benzo[b]thieno[2,3-d]thiophene-2-carboxylic acid,3-(carboxymethoxy)-	Ki	1100000.0 [1]
	2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acid	IC50	50000.0 [1]
	2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2,4-Dimethoxy-6-propylbenzoic acid	IC50	20000.0 [1]
	5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazole	IC50	120000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-f-lar-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Receptor-type tyrosine-protein phosphatase F (LAR) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/receptor-type-tyrosine-protein-phosphatase-f-lar-inhibitors-ic50-ki.
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