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Retinal dehydrogenase 2 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
(3E,5E,7E,9E)-1,1-Dichloro-4,8-dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,5,7,9-tetraen-2-oneIC50191.32 [1]
(3E,5E,7E,9E)-1,1-Dichloro-4,8-dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,5,7,9-tetraen-2-oneKi64.35 [1]
DaidzinIC504500.0 [1]
FertilysinKi56.0 [1]
7-Diethylamino-4-methylcoumarinIC5010000.0 [1]
Methyl 4-(7-butyl-1,3-dimethyl-2,6-dioxopurin-8-yl)oxybenzoateIC50100000.0 [1]
7-Butyl-8-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1,3-dimethylpurine-2,6-dioneIC50100000.0 [1]
8-{[Benzyl(methyl)amino]methyl}-1,3-dimethyl-7-(3-methylbutyl)-3,7-dihydro-1H-purine-2,6-dioneIC50100000.0 [1]
2,3-Dimethyl-5-propyl-7H-furo[3,2-g]chromen-7-oneIC5069.0 [1]
8,9-Dimethyl-2,3-dihydrocyclopenta[c]furo[3,2-g]chromen-4(1H)-oneIC50130.0 [1]
2,3,5-Trimethyl-6-Propyl-7h-Furo[3,2-G][1]benzopyran-7-OneIC50300.0 [1]
2,3,5-Trimethyl-6-[3-Oxo-3-(Piperidin-1-Yl)propyl]-7h-Furo[3,2-G][1]benzopyran-7-OneIC501600.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-2-(oxetan-3-yl)-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC50250.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(2-methylphenyl)-2-(oxetan-3-yl)pyrazolo[3,4-d]pyrimidin-4-oneIC508000.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-2-methyl-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC50340.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-2-methyl-5-(2-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-oneIC506000.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-1-methyl-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC50150.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-1-(oxetan-3-yl)-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC50230.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(2-methylphenyl)-1-(oxetan-3-yl)pyrazolo[3,4-d]pyrimidin-4-oneIC506000.0 [1]
5-Benzyl-6-[(3-fluorophenyl)methylsulfanyl]-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC50720.0 [1]
5-(3-Chlorophenyl)-6-[(3-fluorophenyl)methylsulfanyl]-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC50560.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-1-methyl-5-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-4-oneIC50900.0 [1]
5-(4-Chlorophenyl)-6-[(3-fluorophenyl)methylsulfanyl]-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC501100.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-oneIC50670.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-2-(oxetan-3-ylmethyl)-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC50480.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-1-(oxetan-3-ylmethyl)-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC501100.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(3-methoxyphenyl)-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC501300.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(4-methoxyphenyl)-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC501770.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(2-methylphenyl)-2-(oxetan-3-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-oneIC503900.0 [1]
1-(Cyclopropylmethyl)-6-[(3-fluorophenyl)methylsulfanyl]-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC501260.0 [1]
1-(Cyclopropylmethyl)-6-[(3-fluorophenyl)methylsulfanyl]-5-(2-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-oneIC5010000.0 [1]
2-(Cyclopropylmethyl)-6-[(3-fluorophenyl)methylsulfanyl]-5-(2-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-oneIC5010000.0 [1]
6-[(3-Fluorophenyl)methylsulfanyl]-5-(2-methoxyphenyl)-1-methylpyrazolo[3,4-d]pyrimidin-4-oneIC5010000.0 [1]
2-(Cyclopropylmethyl)-6-[(3-fluorophenyl)methylsulfanyl]-5-phenylpyrazolo[3,4-d]pyrimidin-4-oneIC501100.0 [1]
3-Benzyl-4-methyl-2-oxo-2H-chromen-7-yl methanesulfonateIC5011000.0 [1]
8-(4-Benzylpiperazin-1-yl)-7-(3-chlorobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dioneIC50100000.0 [1]
2,3,5,6-Tetramethyl-7H-furo[3,2-g]chromen-7-oneIC50330.0 [1]
3,5-Dimethyl-6-propyl-7H-furo[3,2-g]chromen-7-oneIC50760.0 [1]
9,10-Dimethyl-1,2,3,4-tetrahydro-5H-benzo[c]furo[3,2-g]chromen-5-oneIC5065.0 [1]
Items per page: 1 - 10 of 39
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References

This online tool may be cited as follows

MLA

"Quest Database™ Retinal dehydrogenase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/retinal-dehydrogenase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Retinal dehydrogenase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/retinal-dehydrogenase-2-inhibitors-ic50-ki.
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