 | Tretinoin | IC50 | 0.9 [1], 0.94 [2], 13.0 [3], 3000.0 [4] |
| Tretinoin | Ki | 0.4 [1], 0.5 [2], 4.1 [3], 7.0 [4], 17.4 [5] |
 | Bexarotene | Ki | 1000.0 [1], 5353.0 [2] |
 | Alitretinoin | IC50 | 7.0 [1] |
| Alitretinoin | Ki | 0.5 [1], 0.7 [2], 10.9 [3] |
 | Ttnpb | IC50 | 5.0 [1] |
| Ttnpb | Ki | 0.5 [1], 5.0 [2] |
 | Adapalene | Ki | 34.0 [1] |
 | 6-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl)nicotinic acid | Ki | 1000.0 [1], 9901.0 [2] |
 | (2E,4E,6Z)-7-[3,5-Ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 4687.0 [1], 9513.0 [2] |
 | 6-(1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid | Ki | 13.0 [1] |
 | 6-(3-Tert-butyl-4-hydroxyphenyl)-2-naphthoic acid | Ki | 3000.0 [1], 3550.0 [2] |
 | (2E,4E)-3-Methyl-5-[2-[(E)-2-(3,3,6,6-tetramethylcyclohexen-1-yl)ethenyl]cyclopropyl]penta-2,4-dienoic acid | Ki | 11.0 [1], 13.0 [2] |
 | (2Z,4E)-3-Methyl-5-[2-[(E)-2-(3,3,6,6-tetramethylcyclohexen-1-yl)ethenyl]cyclopropyl]penta-2,4-dienoic acid | Ki | 1100.0 [1], 1200.0 [2] |
 | Tamibarotene | Ki | 30.0 [1] |
 | 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic Acid | Ki | 2480.0 [1] |
 | 4-[2-[5,5-Dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoic acid | IC50 | 20.0 [1] |
 | 4-(2,18,18,21,21-Pentamethyl-2,14-diazapentacyclo[13.8.0.03,12.04,9.017,22]tricosa-1(15),3(12),4,6,8,10,13,16,22-nonaen-13-yl)benzoic acid | Ki | 500.0 [1] |
 | 4-(5,7,7,10,10-Pentamethyl-8,9-dihydronaphtho[2,3-b][1,4]benzodiazepin-13-yl)benzoic acid | Ki | 220.0 [1] |
 | (2E,4E,6Z)-3-Methyl-7-(5,5,8,8-tetramethyl-3-propoxy-6,7-dihydronaphthalen-2-yl)octa-2,4,6-trienoic acid | Ki | 2587.0 [1] |
 | 4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid | Ki | 3.0 [1] |
 | 4-(7,7,10,10-Tetramethyl-8,9-dihydronaphtho[2,3-b][1,5]benzothiazepin-12-yl)benzoic acid | Ki | 320.0 [1] |
 | 4-(5,7,7,10,10-Pentamethyl-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid | Ki | 680.0 [1] |
 | 6-(4-Methoxy-3-(1-methylcyclohexyl)phenyl)-2-naphthalenecarboxylic acid | Ki | 26.0 [1] |
 | 7-(3,5-Ditert-butylphenyl)-3-methylocta-2,4,6-trienoic acid | Ki | 0.7 [1] |
 | Benzoic acid, 4-(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-2-thiazolyl)- | IC50 | 21.0 [1] |
 | 6-[[3-[(2S)-1-Methoxypropan-2-yl]oxy-5-[(2S)-1-phenylpropan-2-yl]oxybenzoyl]amino]pyridine-3-carboxylic acid | IC50 | 32000.0 [1] |
 | 4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid | Ki | 10000.0 [1] |
 | 4-[5-(4-Phenyl-8-propan-2-ylquinolin-2-yl)-1H-pyrrol-2-yl]benzoic acid | IC50 | 3000.0 [1] |
 | 4-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propenyl) benzoic acid | IC50 | 1169.0 [1] |
 | (2E,4E,6E,8E)-3,7-Dimethyl-9-[2,6,6-trimethyl-3-(1,2,4-triazol-1-yl)cyclohexen-1-yl]nona-2,4,6,8-tetraenoic acid | IC50 | 1000000.0 [1] |
 | Benzoic acid, 4-(5-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1H-pyrrol-2-yl)- | IC50 | 230.0 [1] |
 | 4-((+/-)-(1H-Imidazol-1-yl)-(E)-retinoic acid | IC50 | 175000.0 [1] |
 | (2E,4E,6E,8E)-3,7-Dimethyl-9-[2,6,6-trimethyl-3-(1,2,4-triazol-4-yl)cyclohexen-1-yl]nona-2,4,6,8-tetraenoic acid | IC50 | 250000.0 [1] |
 | 4-[(5,5,8,8-Tetramethyl-6,7-dihydroquinoxaline-2-carbonyl)amino]benzoic acid | IC50 | 140.0 [1] |
 | 4-[(E)-2-(3-Tert-Butyl-4-methoxy-phenyl)-propenyl]-benzoic acid | Ki | 12.0 [1] |
 | (S)-6-(3-(3,5-Difluorophenoxy)-5-(1-methoxypropan-2-yloxy)benzamido)nicotinic acid | IC50 | 1.0 [1] |
 | (2E,4E,6E)-7-[3,5-Ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-6-fluoro-3-methylocta-2,4,6-trienoic acid | Ki | 5681.0 [1] |
 | 4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid | Ki | 909.0 [1] |
 | (2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-5-(2-fluorophenyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 3927.0 [1] |
 | 4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | IC50 | 75.0 [1] |
 | (2E,4E)-5-[2-[3,5-Di(propan-2-yl)-2-(2,2,2-trifluoroethoxy)phenyl]cyclopenten-1-yl]-3-methylpenta-2,4-dienoic acid | Ki | 4742.0 [1] |
 | 6-(3-Isobutoxy-5-isopropoxy-benzoylamino)-nicotinic acid | IC50 | 135.0 [1] |
 | 4-(7,7,10,10-Tetramethyl-8,9-dihydronaphtho[2,3-b][1,5]benzoxazepin-12-yl)benzoic acid | Ki | 320.0 [1] |
 | 4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-anthracen-2-yl)-benzoic acid | IC50 | 22.0 [1] |
 | 4-[5,5-Dimethyl-8-(5-methyl-2-thienyl)-5,6-dihydroanthracene-2-yl]benzoic acid | IC50 | 15.0 [1] |
 | 6-[3-Adamantan-1-yl-4-(1,2-dihydroxy-ethyl)-phenyl]-naphthalene-2-carboxylic acid | Ki | 288.0 [1] |
 | 6-[3-Adamantan-1-yl-4-(2,3-dihydroxy-propoxy)-phenyl]-naphthalene-2-carboxylic acid | Ki | 89.0 [1] |
 | 4-{(E)-4-[2-(4-Tert-Butyl-phenyl)-6,6-dimethyl-cyclohex-1-enyl]-but-3-en-1-ynyl}-benzoic acid | IC50 | 25.0 [1] |
 | 4-(8,8,11,11-Tetramethyl-10,13-dihydro-9H-naphtho[2,3-c][1]benzazepin-6-yl)benzoic acid | Ki | 810.0 [1] |
 | 4-[(E)-2-(3-Isopropyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | IC50 | 150.0 [1] |
 | 4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-dienyl)-but-3-en-1-ynyl]-benzoic acid | IC50 | 53.0 [1] |
 | 4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-propenyl]-benzoic acid | Ki | 1245.0 [1] |
 | 6-[3-(1-Adamantyl)-4-(2,3-dihydroxypropyl)phenyl]-2-naphthoic acid | Ki | 158.0 [1] |
 | 4-(2,2-Dimethyl-4-p-tolyl-2H-1-thia-anthracen-6-yl)-benzoic acid | IC50 | 2.0 [1] |
 | 4-[(E)-2-(3-Tert-butyl-4-hydroxyphenyl)propenyl]benzoic acid | Ki | 105.0 [1] |
 | 4-[(E)-2-[3-(1-Adamantyl)-4-hydroxyphenyl]ethenyl]benzoic acid | Ki | 70.0 [1] |
 | 4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)thiophen-3-yl]benzoic acid | IC50 | 4.5 [1] |
 | 4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)furan-3-yl]benzoic acid | IC50 | 2.5 [1] |
 | 4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)thiophen-2-yl]benzoic acid | IC50 | 36.0 [1] |
 | 4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)furan-2-yl]benzoic acid | IC50 | 39.0 [1] |
 | (2E,4E,6Z)-7-(3-Ethoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-3-methylocta-2,4,6-trienoic acid | Ki | 3115.0 [1] |
 | 4-{(E)-2-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl]-propenyl}-benzoic acid | Ki | 90.0 [1] |
 | 4-[(E)-2-(3-(1-Methylcyclohexyl)-4-methoxyphenyl)propenyl]benzoic acid | Ki | 17.0 [1] |
 | 4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)-1H-pyrazol-3-yl]benzoic acid | IC50 | 290.0 [1] |
 | 6-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl]-naphthalene-2-carboxylic acid | Ki | 660.0 [1] |
 | 4-[(E)-2-(3-Adamantan-1-yl-4-methoxy-phenyl)-propenyl]-benzoic acid | Ki | 105.0 [1] |
 | 6-(3-Adamantan-1-yl-4-carboxy-phenyl)-naphthalene-2-carboxylic acid | Ki | 10000.0 [1] |
 | 6-[3-(1-Adamantyl)-4-(3-hydroxypropyl)phenyl]-2-naphthoic acid | Ki | 21.0 [1] |
 | (2E,4E)-5-[3-[3,5-Di(propan-2-yl)-2-(2,2,2-trifluoroethoxy)phenyl]pyridin-4-yl]-3-methylpenta-2,4-dienoic acid | Ki | 2056.0 [1] |
 | (2E,4E)-5-[3-[2-(3-Fluoropropoxy)-3,5-di(propan-2-yl)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid | Ki | 10000.0 [1] |
 | (2E,4E)-5-[3-[3,5-Di(propan-2-yl)-2-(2,2,2-trifluoroethoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid | Ki | 10000.0 [1] |
 | (2E,4E)-5-[3-[3,5-Ditert-butyl-2-(3,3-difluoropropoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid | Ki | 10000.0 [1] |
 | (2E,4E,6E,8E)-3,7-Dimethyl-1-(1,2,4-triazol-1-yl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-one | IC50 | 90000.0 [1] |
 | (2Z,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid | IC50 | 175000.0 [1] |
 | (2E,4E,6E,8E)-1-Imidazol-1-yl-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-one | IC50 | 500000.0 [1] |
 | (2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-3-methylocta-2,4,6-trienoic acid | Ki | 400.0 [1] |
 | 6-(3-Adamantan-1-yl-4-hexyloxy-phenyl)-naphthalene-2-carboxylic acid | Ki | 10000.0 [1] |
 | 4-[5-(1,1,4,4-Tetramethyltetralin-6-yl)-1H-pyrrole-2-yl]benzoic acid | IC50 | 100.0 [1] |
 | (2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-3-propan-2-yl-5-thiophen-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 2112.0 [1] |
 | (2E,4E,6E)-7-[2-Butoxy-3,5-di(propan-2-yl)phenyl]-6-fluoro-3-methylocta-2,4,6-trienoic acid | Ki | 4623.0 [1] |
 | (2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-5-(3-fluorophenyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 3597.0 [1] |
 | (2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-5-(3,5-difluorophenyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 1956.0 [1] |
 | (2E,4E,6Z)-3-Methyl-7-[3-(1,1,2,2,2-pentafluoroethyl)-5-propan-2-yl-2-propoxyphenyl]octa-2,4,6-trienoic acid | Ki | 10000.0 [1] |
 | (2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-3-phenyl-5-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 2612.0 [1] |
 | (2E,4E,6Z)-3-Methyl-7-[5-(1,1,2,2,2-pentafluoroethyl)-3-propan-2-yl-2-propoxyphenyl]octa-2,4,6-trienoic acid | Ki | 1984.0 [1] |
 | (2E,4E,6Z)-7-[2-Ethoxy-5-(1,1,2,2,2-pentafluoroethyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 10000.0 [1] |
 | 6-(4,4-Dimethyl-chroman-6-yl)-naphthalene-2-carboxylic acid | Ki | 210.0 [1] |
 | 6-[3,5-Bis-(2-fluoro-benzyloxy)-benzoylamino]-nicotinic acid | IC50 | 7.0 [1] |
 | (2E,4E)-2,4-Dimethyl-5-(6,6,9,9-tetramethyl-4-oxo-7,8-dihydrobenzo[g]chromen-3-yl)penta-2,4-dienoic acid | IC50 | 40.0 [1] |
 | 6-(3-Tert-butyl-4-methoxyphenyl)naphthalene-2-carboxylic acid | Ki | 36.0 [1] |
 | 4-[(E)-4-(6,6-Dimethyl-2-p-tolyl-cyclohex-1-enyl)-but-3-en-1-ynyl]-benzoic acid | IC50 | 22.0 [1] |
 | (2E,4E)-5-[3-[2-(2,2-Difluoroethoxy)-3,5-di(propan-2-yl)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid | Ki | 4064.0 [1] |
 | (2E,4E)-5-[2-[3,5-Ditert-butyl-2-(3-fluoropropoxy)phenyl]phenyl]-3-methylpenta-2,4-dienoic acid | Ki | 10000.0 [1] |
 | 6-(3-Adamantan-1-yl-4-hydroxymethyl-phenyl)-naphthalene-2-carboxylic acid | Ki | 156.0 [1] |
 | 4-[2,2-Dimethyl-4-(5-methyl-thiophen-2-yl)-2H-benzo[g]chromen-7-yl]-benzoic acid | IC50 | 6.5 [1] |
 | (2E,4E,6Z)-7-[2-Butoxy-5-(1,1,2,2,2-pentafluoroethyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid | Ki | 2270.0 [1] |
 | 4-[(Z)-(Hydroxyimino)(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-yl)methyl]benzoic acid | Ki | 10000.0 [1] |
 | 4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex-1-enyl]-but-3-en-1-ynyl}-benzoic acid | IC50 | 40.0 [1] |
 | (2E,4E)-5-[2-[2-(2,2-Difluoroethoxy)-3,5-di(propan-2-yl)phenyl]cyclopenten-1-yl]-3-methylpenta-2,4-dienoic acid | Ki | 10000.0 [1] |
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