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Retinoic acid receptor gamma Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
TretinoinIC500.5 [1], 0.62 [2], 18.0 [3]
TretinoinKi0.5 [1], 18.5 [2]
BexaroteneKi130.0 [1], 1000.0 [2], 3206.0 [3]
AlitretinoinIC5017.0 [1]
AlitretinoinKi1.0 [1], 20.0 [2]
(2E,4E,6Z)-7-[3,5-Ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-3-methylocta-2,4,6-trienoic acidKi9513.0 [1], 10000.0 [2]
AdapaleneKi130.0 [1]
TtnpbIC5026.0 [1]
TtnpbKi5.0 [1]
6-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl)nicotinic acidKi9901.0 [1], 10000.0 [2]
6-(1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acidKi40.0 [1]
6-(3-Tert-butyl-4-hydroxyphenyl)-2-naphthoic acidKi200.0 [1]
7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-methyl-octa-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6E)-7-[3,5-Ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-6-fluoro-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-methyl-octa-2,4,6-trienoic acidKi10000.0 [1]
7-(3,5-Di-tert-butyl-2-ethoxy-phenyl)-3-methyl-octa-2,4,6-trienoic acidKi8566.0 [1], 10000.0 [2]
4-[3-(2,6-Dichlorophenoxy)indazol-1-yl]cyclohexane-1-carboxylic acidIC5010000.0 [1]
Rosiglitazone maleateKi10000.0 [1]
FenretinideKi400.0 [1]
6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic AcidKi77.0 [1]
4-[2-[5,5-Dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoic acidIC503.0 [1]
4-(2,18,18,21,21-Pentamethyl-2,14-diazapentacyclo[13.8.0.03,12.04,9.017,22]tricosa-1(15),3(12),4,6,8,10,13,16,22-nonaen-13-yl)benzoic acidKi490.0 [1]
(2E,4E,6Z)-3-Methyl-7-(5,5,8,8-tetramethyl-3-propoxy-6,7-dihydronaphthalen-2-yl)octa-2,4,6-trienoic acidKi6094.0 [1]
4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acidKi2.0 [1]
6-(4-Methoxy-3-(1-methylcyclohexyl)phenyl)-2-naphthalenecarboxylic acidKi160.0 [1]
7-(3,5-Ditert-butylphenyl)-3-methylocta-2,4,6-trienoic acidKi1.9 [1]
2-[2-[(S)-(3,5-Dimethyl-1,2-oxazol-4-yl)-hydroxymethyl]-1-benzofuran-5-yl]-N-[(S)-(2,4-dimethylphenyl)-phenylmethyl]acetamideIC5010000.0 [1]
Benzoic acid, 4-(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-2-thiazolyl)-IC503.6 [1]
6-[[3-[(2S)-1-Methoxypropan-2-yl]oxy-5-[(2S)-1-phenylpropan-2-yl]oxybenzoyl]amino]pyridine-3-carboxylic acidIC501000000.0 [1]
N-[5-(2-Chlorobenzoyl)-4-(3-chlorophenyl)-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamideIC5010000.0 [1]
4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acidKi10000.0 [1]
4-[5-(4-Phenyl-8-propan-2-ylquinolin-2-yl)-1H-pyrrol-2-yl]benzoic acidIC503000.0 [1]
4-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propenyl) benzoic acidIC50645.0 [1]
Benzoic acid, 4-(5-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1H-pyrrol-2-yl)-IC50310.0 [1]
4-[(E)-2-(3-Tert-Butyl-4-methoxy-phenyl)-propenyl]-benzoic acidKi13.0 [1]
(S)-6-(3-(3,5-Difluorophenoxy)-5-(1-methoxypropan-2-yloxy)benzamido)nicotinic acidIC5019000.0 [1]
4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acidKi887.0 [1]
(2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-5-(2-fluorophenyl)-3-propan-2-ylphenyl]-3-methylocta-2,4,6-trienoic acidKi8764.0 [1]
4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acidIC50250.0 [1]
6-(3-Isobutoxy-5-isopropoxy-benzoylamino)-nicotinic acidIC5022000.0 [1]
(E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-1H-indazol-5-yl]-but-2-enoic acidKi10000.0 [1]
(E)-3-[3-[2-(3-Fluoropropoxy)-3,5-di(propan-2-yl)phenyl]-1-benzothiophen-5-yl]but-2-enoic acidKi10000.0 [1]
4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-anthracen-2-yl)-benzoic acidIC502.0 [1]
(E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d]isoxazol-5-yl]-but-2-enoic acidKi10000.0 [1]
4-[5,5-Dimethyl-8-(5-methyl-2-thienyl)-5,6-dihydroanthracene-2-yl]benzoic acidIC502.0 [1]
6-[3-Adamantan-1-yl-4-(1,2-dihydroxy-ethyl)-phenyl]-naphthalene-2-carboxylic acidKi153.0 [1]
(E)-3-[3-[2-Ethoxy-3,5-di(propan-2-yl)phenyl]imidazo[1,2-a]pyridin-6-yl]but-2-enoic acidKi10000.0 [1]
(E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1-methyl-1H-indol-5-yl]-but-2-enoic acidKi10000.0 [1]
(E)-3-[3-(3,5-Ditert-butyl-2-propoxyphenyl)-1H-indol-5-yl]but-2-enoic acidKi10000.0 [1]
6-[3-Adamantan-1-yl-4-(2,3-dihydroxy-propoxy)-phenyl]-naphthalene-2-carboxylic acidKi151.0 [1]
(2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-3,5-di(propan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
4-{(E)-4-[2-(4-Tert-Butyl-phenyl)-6,6-dimethyl-cyclohex-1-enyl]-but-3-en-1-ynyl}-benzoic acidIC50331.0 [1]
(E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[b]thiophen-5-yl]-but-2-enoic acidKi10000.0 [1]
(E)-3-[3-(3,5-Diisopropyl-2-methoxy-phenyl)-benzo[b]thiophen-5-yl]-but-2-enoic acidKi10000.0 [1]
(E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1H-indol-5-yl]-but-2-enoic acidKi10000.0 [1]
(2E,4E,6E)-3-Methyl-7-(2-ethoxy-3,5-di-tert-butylphenyl)-8,8,8-trifluoroocta-2,4,6-trienoic acidKi10000.0 [1]
(E)-3-[3-(2-Butoxy-3,5-ditert-butylphenyl)-1H-indol-5-yl]but-2-enoic acidKi10000.0 [1]
(E)-3-[3-[3,5-Ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-1H-indol-5-yl]but-2-enoic acidKi10000.0 [1]
4-[(E)-2-(3-Isopropyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acidIC501000.0 [1]
4-[(E)-4-(3,3-Dimethyl-6-p-tolyl-cyclohexa-1,5-dienyl)-but-3-en-1-ynyl]-benzoic acidIC5031.0 [1]
4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-propenyl]-benzoic acidKi53.0 [1]
6-[3-(1-Adamantyl)-4-(2,3-dihydroxypropyl)phenyl]-2-naphthoic acidKi34.0 [1]
4-(2,2-Dimethyl-4-p-tolyl-2H-1-thia-anthracen-6-yl)-benzoic acidIC500.5 [1]
4-[(E)-2-(3-Tert-butyl-4-hydroxyphenyl)propenyl]benzoic acidKi85.0 [1]
4-[(E)-2-[3-(1-Adamantyl)-4-hydroxyphenyl]ethenyl]benzoic acidKi20.0 [1]
4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)thiophen-3-yl]benzoic acidIC502.0 [1]
4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)furan-3-yl]benzoic acidIC5027.0 [1]
4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)thiophen-2-yl]benzoic acidIC5017.0 [1]
4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)furan-2-yl]benzoic acidIC504.6 [1]
(2E,4E,6Z)-7-(3-Ethoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-3-methylocta-2,4,6-trienoic acidKi4206.0 [1]
4-{(E)-2-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl]-propenyl}-benzoic acidKi27.0 [1]
4-[5-(5,5,8,8-Tetramethyl-6,7-dihydroquinoxalin-2-yl)-1H-pyrrol-3-yl]benzoic acidIC50150.0 [1]
4-[(E)-2-(3-(1-Methylcyclohexyl)-4-methoxyphenyl)propenyl]benzoic acidKi29.0 [1]
6-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl]-naphthalene-2-carboxylic acidKi121.0 [1]
4-[(E)-2-(3-Adamantan-1-yl-4-methoxy-phenyl)-propenyl]-benzoic acidKi95.0 [1]
6-(3-Adamantan-1-yl-4-carboxy-phenyl)-naphthalene-2-carboxylic acidKi10000.0 [1]
6-[3-(1-Adamantyl)-4-(3-hydroxypropyl)phenyl]-2-naphthoic acidKi72.0 [1]
(2E,4E,6Z)-7-[2-Ethoxy-3,5-bis(2-methylbutan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi2503.0 [1]
(2E,4E,6Z)-7-[2-Methoxy-3,5-di(propan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6Z)-7-[2-(2-Fluoroethoxy)-3,5-di(propan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6Z)-7-[3,5-Bis(2-methylbutan-2-yl)-2-propoxyphenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6Z)-7-[2-Methoxy-3,5-bis(2-methylbutan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
7-(3,5-Diisopropyl-2-propoxy-phenyl)-3-methyl-octa-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-3,5-bis(2-methylbutan-2-yl)phenyl]-3-methylocta-2,4,6-trienoic acidKi10000.0 [1]
(2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-3-methylocta-2,4,6-trienoic acidKi437.0 [1]
6-(3-Adamantan-1-yl-4-hexyloxy-phenyl)-naphthalene-2-carboxylic acidKi10000.0 [1]
4-[3-(2,6-Dichlorophenoxy)indazol-1-yl]-3-fluorobenzoic acidIC5010000.0 [1]
4-[3-(2,6-Dichlorophenoxy)indazol-1-yl]benzoic acidIC501400.0 [1]
N-(4-Ethylphenyl)-N-(2-methylpropyl)-3-(methylsulfonimidoyl)-4-(oxan-4-ylmethoxy)benzenesulfonamideIC5010000.0 [1]
4-[3-[2-Chloranyl-6-(Trifluoromethyl)phenoxy]-5-(Dimethylcarbamoyl)indazol-1-Yl]benzoic AcidIC507200.0 [1]
4-[5-(Dimethylcarbamoyl)-3-(2,4,6-trimethylphenyl)sulfanylindazol-1-yl]benzoic acidIC5010000.0 [1]
4-[3-(2-Chloro-6-methylphenoxy)-5-(dimethylcarbamoyl)indazol-1-yl]benzoic acidIC5010000.0 [1]
4-[5-(Dimethylcarbamoyl)-3-(2-methylphenyl)sulfanylindazol-1-yl]benzoic acidIC5010000.0 [1]
4-[5-[Benzyl(methyl)carbamoyl]-3-(2,6-dichlorophenyl)sulfanylindazol-1-yl]benzoic acidIC5010000.0 [1]
4-[5-(Azetidine-1-carbonyl)-3-(2,6-dichlorophenyl)sulfanylindazol-1-yl]benzoic acidIC504100.0 [1]
4-[3-(2,6-Dichlorophenoxy)-4-fluoroindazol-1-yl]benzoic acidIC50800.0 [1]
4-[3-(2,6-Dichlorophenoxy)-5-(dimethylcarbamoyl)indazol-1-yl]benzoic acidIC5010000.0 [1]
4-[3-(2,6-Dichlorophenyl)sulfanyl-5-(pyrrolidine-1-carbonyl)indazol-1-yl]benzoic acidIC5010000.0 [1]
4-[3-(2,6-Dichlorophenyl)sulfinylindazol-1-yl]benzoic acidIC505600.0 [1]
4-[3-(2,6-Dichlorophenoxy)indazol-1-yl]-3,5-difluorobenzoic acidIC5010000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Retinoic acid receptor gamma Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/retinoic-acid-receptor-gamma-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Retinoic acid receptor gamma Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/retinoic-acid-receptor-gamma-inhibitors-ic50-ki.
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