RNase L Inhibitors (IC50, Ki)

Name: RNase L Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	5'-O-Monophosphoryladenylyl(2'->5')adenylyl(2'->5')adenosine	IC50	1.1 ^[1], 7.3 ^[2], 13.0 ^[3], 20.0 ^[4]
	[4-(6-Aminopurin-9-yl)-3-[[4-(6-aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methoxy-hydroxyphosphoryl]oxy-2-hydroxycyclopentyl]methyl [5-(6-aminopurin-9-yl)-2-hydroxy-3-(phosphonooxymethyl)cyclopentyl] hydrogen phosphate	IC50	210.0 ^[1], 2300.0 ^[2]
	[[(2R,3R,4R,5R)-4-[[(2R,3R,4R,5R)-4-[[(2R,3S,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate	IC50	0.72 ^[1]
	[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-2-(6-amino-2-methylpurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate	IC50	1060.0 ^[1]
	[[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate	IC50	24.0 ^[1]
	[[(2R,3R,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate	IC50	105.0 ^[1]
	[(2R,3R,4R,5R)-2-(6-Amino-2-methylpurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate	IC50	57.0 ^[1]
	[(2R,3R,4R,5R)-4-[[(2R,3S,4R,5R)-5-(6-Amino-2-methylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate	IC50	2.6 ^[1]
	[(2R,3S,4R,5S)-5-(6-Aminopurin-9-yl)-3-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxyoxolan-2-yl]methyl [(2R,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-hydroxy-2-phosphonooxyoxolan-3-yl] hydrogen phosphate	IC50	50000.0 ^[1]
	[(2R,3R,4R,5R)-5-(6-Aminopurin-9-yl)-4-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-phosphonooxyoxolan-3-yl] hydrogen phosphate	IC50	1000.0 ^[1]
	[(2R,3R,4R,5S)-5-(6-Aminopurin-9-yl)-4-[[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-hydroxyoxolan-2-yl]methyl [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-4-hydroxy-5-phosphonooxyoxolan-3-yl] hydrogen phosphate	IC50	50000.0 ^[1]

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MLA	"Quest Database™ RNase L Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/rnase-l-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ RNase L Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/rnase-l-inhibitors-ic50-ki.
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RNase L Inhibitors (IC50, Ki)

References

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