Scavenger mRNA-decapping enzyme DcpS Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	5-{[1-(2-Fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine	IC50	0.03 [1], 7.62 [2]
	5-{[1-(2,3-Dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine	IC50	0.08 [1], 43.94 [2]
	Quinazoline-2,4-diamine	IC50	142.58 [1]
	5-Methoxyquinazoline-2,4-diamine	IC50	7.9 [1]
	2,4-Quinazolinediamine, 5-((1-((2,6-dichlorophenyl)methyl)-4-piperidinyl)methoxy)-	IC50	0.07 [1]
	N(7)-Methylguanosine 5'-phosphate	IC50	42200.0 [1]
	[[(2R,3S,4R,5R)-5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphate	IC50	30.0 [1]
	2,4-Diamino-5-benzyloxy-quinazoline	IC50	1.01 [1]
	5-[(3,5-Difluorophenyl)methoxy]quinazoline-2,4-diamine	IC50	0.19 [1]
	5-((2,4-Difluorophenoxy)methyl)quinazoline-2,4-diamine	IC50	0.02 [1]
	5-[(2-Chlorophenoxy)methyl]quinazoline-2,4-diamine	IC50	0.29 [1]
	5-(3-Chlorobenzyloxy)quinazoline-2,4-diamine	IC50	2.89 [1]
	5-((3-Chlorophenoxy)methyl)quinazoline-2,4-diamine	IC50	0.05 [1]
	[(2R,3S,4R,5R)-5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono phosphate	IC50	1800.0 [1]
	5-((2-Fluorophenoxy)methyl)quinazoline-2,4-diamine	IC50	0.02 [1]
	5-[[1-[(2-Chlorophenyl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	0.11 [1]
	PF-DcpSi	IC50	0.11 [1]
	5-(Oxan-4-ylmethoxy)quinazoline-2,4-diamine	IC50	1.77 [1]
	5-[(2-Methylpyridin-3-yl)oxymethyl]quinazoline-2,4-diamine	IC50	0.27 [1]
	5-[(3-Fluorophenoxy)methyl]quinazoline-2,4-diamine	IC50	0.25 [1]
	5-(Oxan-4-yloxymethyl)quinazoline-2,4-diamine	IC50	2.3 [1]
	5-[(2R)-1-Methoxypropan-2-yl]oxyquinazoline-2,4-diamine	IC50	16.2 [1]
	5-[(2S)-1-Methoxypropan-2-yl]oxyquinazoline-2,4-diamine	IC50	13.59 [1]
	7-Methyl-5-(oxan-4-ylmethoxy)quinazoline-2,4-diamine	IC50	10000.0 [1]
	5-[[1-[(2,6-Dichlorophenyl)methyl]piperidin-4-yl]methoxy]-7-methylquinazoline-2,4-diamine	IC50	334.3 [1]
	3-[(2,4-Diamino-7-methylquinazolin-5-yl)methoxy]-5-fluorobenzonitrile	IC50	10000.0 [1]
	5-[[1-[(2-Fluorophenyl)methyl]piperidin-4-yl]methoxy]-7-methylquinazoline-2,4-diamine	IC50	12.31 [1]
	5-[[1-[(2-Chloro-6-fluorophenyl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	0.04 [1]
	5-[[1-[(3,4-Dichlorophenyl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	0.32 [1]
	5-[(1-Benzylpiperidin-4-yl)methoxy]quinazoline-2,4-diamine	IC50	0.03 [1]
	5-[(3-Methyloxetan-3-yl)methoxy]quinazoline-2,4-diamine	IC50	10.55 [1]
	5-[[1-[[2-(Trifluoromethoxy)phenyl]methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	1.39 [1]
	[1-[[(2R,3S,4R,5R)-5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]triazol-4-yl]phosphonic acid	IC50	244000.0 [1]
	5-[[1-(2-Chlorophenyl)piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	101.34 [1]
	N-[4-[[4-[(2,4-Diaminoquinazolin-5-yl)oxymethyl]piperidin-1-yl]methyl]-1,3-thiazol-2-yl]acetamide	IC50	339.45 [1]
	5-[[1-(2,2,2-Trifluoroethyl)piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	23.35 [1]
	5-[[1-[(1-Methylimidazol-2-yl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine	IC50	9.38 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 37 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Scavenger mRNA-decapping enzyme DcpS Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/scavenger-mrna-decapping-enzyme-dcps-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Scavenger mRNA-decapping enzyme DcpS Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/scavenger-mrna-decapping-enzyme-dcps-inhibitors-ic50-ki.
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