Serine/threonine-protein kinase EEF2K Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide	IC50	280.0 [1], 420.0 [2], 510.0 [3]
	2-((3,5-Dimethyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione	IC50	440.0 [1]
	Entrectinib	IC50	10000.0 [1]
	Nms-P937 (nms1286937)	IC50	10000.0 [1]
	5-[2,4-Dihydroxy-6-(4-Nitrophenoxy)phenyl]-N-(1-Methylpiperidin-4-Yl)-1,2-Oxazole-3-Carboxamide	IC50	10.0 [1]
	2-((3,5-Di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione	IC50	3200.0 [1]
	3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide	IC50	2500.0 [1]
	5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide	IC50	10000.0 [1]
	2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide	IC50	10000.0 [1]
	6-Amino-8-(furan-2-yl)-4-thia-2-azatricyclo[7.7.0.03,7]hexadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	170.0 [1]
	3-[[5-(1,3-Benzodioxol-5-yl)-[1,2,4]triazolo[1,5-c]quinazolin-8-yl]amino]propan-1-ol	IC50	10000.0 [1]
	7-Amino-1,3-diethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	1000.0 [1]
	6-Amino-1-cyclopropyl-3-ethylpyrimidine-2,4-dione	IC50	25000.0 [1]
	6-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrimidine-5-carbaldehyde	IC50	25000.0 [1]
	7-Amino-1-cyclopropyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	6600.0 [1]
	7-Amino-1-cyclopropyl-3-methyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	6100.0 [1]
	7-Amino-1-cyclopropyl-2,4-dioxo-3-propylpyrido[2,3-d]pyrimidine-6-carboxamide	IC50	930.0 [1]
	7-Amino-1-cyclopropyl-3-[(4-nitrophenyl)methyl]-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	25000.0 [1]
	7-Amino-3-[(4-aminophenyl)methyl]-1-cyclopropyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	25000.0 [1]
	7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carbothioamide	IC50	25000.0 [1]
	7-Amino-1,3-dimethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide	IC50	25000.0 [1]
	5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide	IC50	10.0 [1]
	5-[2,4-Dihydroxy-6-[4-(propan-2-ylamino)phenoxy]phenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide	IC50	10.0 [1]
	5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-[1-(1,4-dioxaspiro[4.5]decan-8-yl)piperidin-4-yl]-1,2-oxazole-3-carboxamide	IC50	10.0 [1]
	1-Benzyl-3-hexadecyl-2-methyl-4,5-dihydroimidazol-1-ium;iodide	IC50	60.0 [1]
	3-(2,4-Dichlorophenyl)-3-[(4-fluorobenzoyl)amino]propanoic acid	IC50	17100.0 [1]
	3-[(3-Bromobenzoyl)amino]-3-(2,4-dichlorophenyl)propanoic acid	IC50	28400.0 [1]
	3-(2,4-Dichlorophenyl)-3-[(3,5-difluorophenyl)sulfonylamino]propanoic acid	IC50	12500.0 [1]
	3-(2-Fluorophenyl)-3-[[4-(trifluoromethyl)phenyl]sulfonylamino]propanoic acid	IC50	11600.0 [1]
	3-[(3-Bromobenzoyl)amino]-3-(2-fluorophenyl)propanoic acid	IC50	50000.0 [1]
	3-[(2,4-Dichlorobenzoyl)amino]-3-(2-fluorophenyl)propanoic acid	IC50	33700.0 [1]
	3-(4-Tert-butylphenyl)-3-[(4-fluorophenyl)sulfonylamino]propanoic acid	IC50	38500.0 [1]
	3-[(4-Cyanophenyl)sulfonylamino]-3-(2-fluorophenyl)propanoic acid	IC50	27500.0 [1]
	3-(2,4-Dichlorophenyl)-3-[(2-methoxybenzoyl)amino]propanoic acid	IC50	50000.0 [1]
	3-(Benzenesulfonamido)-3-(2-fluorophenyl)propanoic acid	IC50	50000.0 [1]
	3-(Benzenesulfonamido)-3-(2,4-dichlorophenyl)propanoic acid	IC50	33400.0 [1]
	3-(4-Tert-butylphenyl)-3-[[4-(trifluoromethoxy)phenyl]sulfonylamino]propanoic acid	IC50	50000.0 [1]
	3-[(2,6-Dichlorobenzoyl)amino]-3-phenylpropanoic acid	IC50	50000.0 [1]
	3-(2-Fluorophenyl)-3-[[4-(trifluoromethyl)benzoyl]amino]propanoic acid	IC50	44500.0 [1]
	3-[(2,4-Dichlorobenzoyl)amino]-3-(2,4-dichlorophenyl)propanoic acid	IC50	19900.0 [1]
	3-[(2-Bromophenyl)sulfonylamino]-3-(2,4-dichlorophenyl)propanoic acid	IC50	50000.0 [1]
	3-(4-Tert-butylphenyl)-3-[[4-(trifluoromethyl)benzoyl]amino]propanoic acid	IC50	22600.0 [1]
	3-[(4-Fluorobenzoyl)amino]-3-(2-fluorophenyl)propanoic acid	IC50	36700.0 [1]
	3-(4-Tert-butylphenyl)-3-[(2-methoxybenzoyl)amino]propanoic acid	IC50	50000.0 [1]
	3-(4-Tert-butylphenyl)-3-[(2,6-dichlorobenzoyl)amino]propanoic acid	IC50	50000.0 [1]
	3-[(4-Cyanophenyl)sulfonylamino]-3-(2,4-dichlorophenyl)propanoic acid	IC50	5500.0 [1]
	3-(2,4-Dichlorophenyl)-3-[(4-methoxybenzoyl)amino]propanoic acid	IC50	44400.0 [1]
	3-(2,4-Dichlorophenyl)-3-[[4-(trifluoromethyl)benzoyl]amino]propanoic acid	IC50	11700.0 [1]
	3-[(2,6-Dichlorobenzoyl)amino]-3-(2,4-dichlorophenyl)propanoic acid	IC50	50000.0 [1]
	3-(Benzenesulfonamido)-3-(4-tert-butylphenyl)propanoic acid	IC50	50000.0 [1]
	3-[(3,5-Difluorophenyl)sulfonylamino]-3-(2-fluorophenyl)propanoic acid	IC50	19400.0 [1]
	3-(2,4-Dichlorophenyl)-3-[(3-nitrophenyl)sulfonylamino]propanoic acid	IC50	44500.0 [1]
	3-(4-Tert-butylphenyl)-3-[[4-(trifluoromethyl)phenyl]sulfonylamino]propanoic acid	IC50	18400.0 [1]
	3-(4-Tert-butylphenyl)-3-[(2-methoxyphenyl)sulfonylamino]propanoic acid	IC50	50000.0 [1]
	3-(2,4-Dichlorophenyl)-3-[[4-(trifluoromethyl)phenyl]sulfonylamino]propanoic acid	IC50	9500.0 [1]
	1-(3-Chlorophenyl)-3-[4-[2-(ethylamino)pyridin-4-yl]-3-(trifluoromethyl)phenyl]urea	IC50	762.0 [1]
	7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carbonitrile	IC50	25000.0 [1]
	Ethyl 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxylate	IC50	25000.0 [1]
	3-[(2-Methoxybenzoyl)amino]-3-phenylpropanoic acid	IC50	50000.0 [1]
	3-[(4-Fluorobenzoyl)amino]-3-phenylpropanoic acid	IC50	35100.0 [1]
	3-[(2,4-Dichlorobenzoyl)amino]-3-phenylpropanoic acid	IC50	29300.0 [1]
	3-[(3-Bromophenyl)formamido]-3-phenylpropanoic acid	IC50	50000.0 [1]
	3-{[(3-Nitrophenyl)sulfonyl]amino}-3-phenylpropanoic acid	IC50	50000.0 [1]
	3-{[(4-Fluorophenyl)sulfonyl]amino}-3-phenylpropanoic acid	IC50	31200.0 [1]
	3-Phenyl-3-[(phenylsulfonyl)amino]propanoic acid	IC50	50000.0 [1]
	Chembl4169894	IC50	31600.0 [1]
	8-[(1-Acetylpiperidin-4-yl)amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide	IC50	10000.0 [1]
	8-[(1-Benzoylpiperidin-4-yl)amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide	IC50	10000.0 [1]
	3-[(3,5-Difluorophenyl)sulfonylamino]-3-phenylpropanoic acid	IC50	37800.0 [1]
	3-[(2-Bromophenyl)sulfonylamino]-3-phenylpropanoic acid	IC50	50000.0 [1]
	3-[(4-Cyanophenyl)sulfonylamino]-3-phenylpropanoic acid	IC50	18700.0 [1]
	3-Phenyl-3-[[4-(trifluoromethoxy)phenyl]sulfonylamino]propanoic acid	IC50	50000.0 [1]
	3-Phenyl-3-[[4-(trifluoromethyl)phenyl]sulfonylamino]propanoic acid	IC50	19600.0 [1]
	3-{[(4-Tert-butylphenyl)sulfonyl]amino}-3-phenylpropanoic acid	IC50	50000.0 [1]
	N,1-Dimethyl-8-[[1-(1-methylsulfonylpiperidine-4-carbonyl)piperidin-4-yl]amino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide	IC50	10000.0 [1]
	6-Amino-8-[(E)-2-(furan-2-yl)ethenyl]-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	320.0 [1]
	6-Amino-8-methyl-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1,3(7),5,8-tetraene-5-carboxamide	IC50	1100.0 [1]
	6-Amino-8-(2-methylpropyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	860.0 [1]
	6-Amino-8-cyclopropyl-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	2000.0 [1]
	6-Amino-8-(6-methylhept-5-en-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	10000.0 [1]
	6-Amino-8-(3,4-dichlorophenyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	990.0 [1]
	6-Amino-8-(4-chlorophenyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1100.0 [1]
	6-Amino-8-phenyl-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	20000.0 [1]
	4-(6-Amino-5-carbamoyl-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraen-8-yl)benzoic acid	IC50	860.0 [1]
	6-Amino-8-(2-fluoro-5-methoxyphenyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1300.0 [1]
	6-Amino-8-(3-methylphenyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1200.0 [1]
	6-Amino-8-(furan-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	640.0 [1]
	6-Amino-8-(3-methylthiophen-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	460.0 [1]
	6-Amino-8-pyridin-3-yl-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	940.0 [1]
	6-Amino-8-(1-methylpyrrol-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	990.0 [1]
	6-Amino-8-(furan-3-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1100.0 [1]
	6-Amino-8-(1,3-thiazol-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1400.0 [1]
	6-Amino-8-(3-methylpyridin-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	20000.0 [1]
	6-Amino-8-(2-phenylethyl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	20000.0 [1]
	6-Amino-8-(5-chlorofuran-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	280.0 [1]
	6-Amino-8-[5-(trifluoromethyl)furan-2-yl]-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	300.0 [1]
	6-Amino-8-(1-benzofuran-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	330.0 [1]
	6-Amino-8-(5-ethylfuran-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	660.0 [1]
	6-Amino-8-[5-(hydroxymethyl)furan-2-yl]-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	800.0 [1]
	6-Amino-8-(4,5-dimethylfuran-2-yl)-4-thia-2-azatricyclo[7.6.0.03,7]pentadeca-1(9),2,5,7-tetraene-5-carboxamide	IC50	1100.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase EEF2K Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-eef2k-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Serine/threonine-protein kinase EEF2K Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-eef2k-inhibitors-ic50-ki.
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