Serine/threonine-protein kinase ILK-1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(4E)-4-[4-(1,3-Benzothiazol-2-yl)-1,2-dihydropyrazol-3-ylidene]-3-hydroxycyclohexa-2,5-dien-1-one	IC50	3300.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-methyl-1,3-benzothiazole-5-sulfonamide	IC50	1900.0 [1]
	4-(4-Benzothiazol-2-YL-1H-pyrazol-3-YL)phenol	IC50	3400.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-(1H-imidazol-2-ylmethylideneamino)-1H-pyrazol-5-amine	IC50	1000.0 [1]
	2-[4-(1,3-Benzothiazol-2-yl)-1H-pyrazol-5-yl]phenol	IC50	4600.0 [1]
	4-(1,3-Benzothiazol-2-yl)-1H-pyrazole-3,5-diamine	IC50	700.0 [1]
	4-Benzothiazol-2-YL-2H-pyrazol-3-ylamine	IC50	300.0 [1]
	4-(1,3-Benzothiazol-2-yl)-5-ethyl-1H-pyrazol-3-amine	IC50	800.0 [1]
	4-(1,3-Benzothiazol-2-yl)-5-phenyl-1H-pyrazol-3-amine	IC50	900.0 [1]
	4-(1,3-Benzothiazol-2-yl)-5-cyclopropyl-1H-pyrazol-3-amine	IC50	600.0 [1]
	4-Benzothiazol-2-YL-5-furan-2-YL-2H-pyrazol-3-ylamine	IC50	100.0 [1]
	4-(1,3-Benzothiazol-2-yl)-5-thiophen-2-yl-1H-pyrazol-3-amine	IC50	900.0 [1]
	3-Methyl-4-(benzothiazole-2-yl)-5-amino-1H-pyrazole	IC50	300.0 [1]
	3-(3-Aminopropyl)-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-5-amine	IC50	10.0 [1]
	4-[5-(Trifluoromethyl)-1,3-benzothiazol-2-yl]-1H-pyrazol-5-amine	IC50	1100.0 [1]
	2-(5-Methyl-1H-pyrazol-4-yl)-1,3-benzothiazole	IC50	900.0 [1]
	2-(1H-Pyrazol-4-yl)benzo[d]thiazole	IC50	1600.0 [1]
	5-Methyl-4-(6-pyrrolidin-1-ylmethyl-benzothiazol-2-YL)-2H-pyrazol-3-ylamine	IC50	900.0 [1]
	5-Cyclopropyl-4-(5-fluoro-6-methoxy-benzothiazol-2-YL)-2H-pyrazol-3-ylamine	IC50	1000.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-3-N-[2-(1H-imidazol-5-yl)ethyl]-1H-pyrazole-3,5-diamine	IC50	200.0 [1]
	4-(6-Methoxy-1,3-benzothiazol-2-yl)-3-piperazin-1-yl-1H-pyrazol-5-amine	IC50	200.0 [1]
	4-[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]butanoic acid	IC50	4300.0 [1]
	3-[[5-Amino-4-(5-fluoro-6-methoxy-1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]propan-1-ol	IC50	500.0 [1]
	4-(6-Methoxy-1,3-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-amine	IC50	340.0 [1]
	4-[2-[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]ethyl]phenol	IC50	2900.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(2-methoxyethyl)-1,3-benzothiazole-6-sulfonamide	IC50	600.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-[2-(1H-imidazol-5-yl)ethyl]-1,3-benzothiazole-6-sulfonamide	IC50	200.0 [1]
	N-[2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-1,3-benzothiazol-6-yl]acetamide	IC50	400.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(2-phenylethyl)-1,3-benzothiazole-6-sulfonamide	IC50	800.0 [1]
	4-(6-Chloro-1,3-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-amine	IC50	300.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-benzyl-1,3-benzothiazole-6-sulfonamide	IC50	800.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(4-fluorophenyl)-1H-pyrazol-3-amine	IC50	2400.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-[2-(dimethylamino)ethyl]-1,3-benzothiazole-6-sulfonamide	IC50	300.0 [1]
	3-N-(2-Aminoethyl)-4-(1,3-benzothiazol-2-yl)-1H-pyrazole-3,5-diamine	IC50	20.0 [1]
	4-(7-Chloro-4-methoxy-1,3-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-amine	IC50	1000.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(2-fluorophenyl)-1H-pyrazol-3-amine	IC50	4000.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-N-(2-hydroxyethyl)-1,3-benzothiazole-4-sulfonamide	IC50	150.0 [1]
	4-(4-Fluorobenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine	IC50	400.0 [1]
	4-(5-Fluorobenzothiazol-2-YL)-5-methyl-2H-pyrazol-3-ylamine	IC50	40.0 [1]
	4-(6-Nitro-1,3-benzothiazol-2-yl)-1H-pyrazol-5-amine	IC50	3400.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrazol-3-amine	IC50	900.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-thiophen-2-yl-1H-pyrazol-3-amine	IC50	700.0 [1]
	[2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluorobenzothiazol-6-yl]methanol	IC50	100.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-(3-imidazol-1-ylpropyl)-1H-pyrazole-3,5-diamine	IC50	500.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-YL)-benzothiazole-6-carboxylic acid methyl ester	IC50	300.0 [1]
	4-(5-Methoxy-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine	IC50	3700.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(cyclopropylmethyl)-1,3-benzothiazole-6-sulfonamide	IC50	700.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-(2-pyrrolidin-1-ylethyl)-1H-pyrazole-3,5-diamine	IC50	1900.0 [1]
	4-(6-Dimethylaminomethyl-5-fluorobenzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine	IC50	600.0 [1]
	4-(5-Fluoro-6-methoxybenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine	IC50	60.0 [1]
	4-[[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]methyl]benzenesulfonamide	IC50	2900.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(pyridin-4-ylmethyl)-1,3-benzothiazole-6-sulfonamide	IC50	40.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(2-hydroxyethyl)-1,3-benzothiazole-6-sulfonamide	IC50	200.0 [1]
	3-[[2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-1,3-benzothiazol-6-yl]methylamino]benzenesulfonamide	IC50	800.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-[2-(ethylamino)ethyl]-1H-pyrazole-3,5-diamine	IC50	150.0 [1]
	5-Methyl-4-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]-1H-pyrazol-3-amine	IC50	2800.0 [1]
	4-Benzothiazol-2-YL-5-piperidin-4-YL-2H-pyrazol-3-ylamine	IC50	60.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-[2-(1H-indol-3-yl)ethyl]-1H-pyrazole-3,5-diamine	IC50	3300.0 [1]
	Methyl 2-(3-amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-1,3-benzothiazole-6-carboxylate	IC50	60.0 [1]
	3-[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]propan-1-ol	IC50	400.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-N-(2-hydroxyethyl)-1,3-benzothiazole-6-sulfonamide	IC50	50.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-6-carboxylic acid	IC50	1100.0 [1]
	5-Methyl-4-[6-(4-methylpiperazin-1-ylmethyl)-benzothiazol-2-yl]-2H-pyrazol-3-ylamine	IC50	5000.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-[3-(dimethylamino)propyl]-1H-pyrazole-3,5-diamine	IC50	300.0 [1]
	N-[2-[[2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-1,3-benzothiazol-6-yl]sulfonylamino]ethyl]acetamide	IC50	700.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(2-thiophen-2-ylethyl)-1,3-benzothiazole-6-sulfonamide	IC50	1700.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-pyrrolidin-1-yl-1H-pyrazol-5-amine	IC50	3700.0 [1]
	4-(1,3-Benzothiazol-2-yl)-N-[2-(1H-imidazol-5-yl)ethyl]-1H-pyrazol-5-amine	IC50	200.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-1,3-benzothiazole-6-sulfonamide	IC50	3000.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(5-nitrofuran-2-yl)-1H-pyrazol-3-amine	IC50	300.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-phenyl-1H-pyrazol-3-amine	IC50	2300.0 [1]
	4-(6-Fluoro-1,3-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-amine	IC50	400.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-3-piperazin-1-yl-1H-pyrazol-5-amine	IC50	70.0 [1]
	2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-chlorobenzylamide	IC50	900.0 [1]
	2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-methoxybenzylamide	IC50	1000.0 [1]
	N-[2-[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]ethyl]acetamide	IC50	1100.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-1,3-benzothiazole-6-sulfonamide	IC50	10.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-piperazin-1-yl-1H-pyrazol-5-amine	IC50	190.0 [1]
	4-(6-Dimethylaminomethylbenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine	IC50	200.0 [1]
	N-[2-[[5-Amino-4-(5-fluoro-6-methoxy-1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]ethyl]acetamide	IC50	1800.0 [1]
	4-Benzothiazol-2-YL-5-(4-nitrophenyl)-2H-pyrazol-3-ylamine	IC50	4000.0 [1]
	4-(5-Fluoro-6-methyl-1,3-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-amine	IC50	300.0 [1]
	4-Benzothiazol-2-YL-5-(3-methylamino-propyl)-2H-pyrazol-3-ylamine	IC50	20.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1H-pyrazol-3-amine	IC50	2000.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(3-fluorophenyl)-1H-pyrazol-3-amine	IC50	2300.0 [1]
	4-[[5-Amino-4-(1,3-benzothiazol-2-yl)-1H-pyrazol-3-yl]amino]butan-1-ol	IC50	1700.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-N-[2-(4-aminophenyl)ethyl]-1,3-benzothiazole-6-sulfonamide	IC50	200.0 [1]
	4-Benzothiazol-2-yl-5-(4-methylaminobutyl)-2H-pyrazol-3-ylamine	IC50	100.0 [1]
	4-(7-Chloro-5-fluoro-6-methoxybenzothiazol-2-YL)-5-methyl-1H-pyrazol-3-ylamine	IC50	400.0 [1]
	2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazol-5-ol	IC50	200.0 [1]
	4-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-yl)butan-1-ol	IC50	1000.0 [1]
	5-Methyl-4-[6-(4-methylpiperazine-1-sulfonyl)-benzothiazol-2-yl]-2H-pyrazol-3-ylamine	IC50	4900.0 [1]
	3-(5-Amino-4-benzothiazol-2-YL-2H-pyrazol-3-YL)-propan-1-OL	IC50	200.0 [1]
	4-(5-Fluoro-6-methyl-1,3-benzothiazol-2-yl)-1H-pyrazol-5-amine	IC50	50.0 [1]
	5-Methyl-4-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-1H-pyrazol-3-amine	IC50	500.0 [1]
	3-N-[3-(Dimethylamino)propyl]-4-(5-fluoro-6-methoxy-1,3-benzothiazol-2-yl)-1H-pyrazole-3,5-diamine	IC50	200.0 [1]
	2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-N-methyl-1,3-benzothiazole-6-sulfonamide	IC50	40.0 [1]
	4-(5-Fluoro-6-methoxy-1,3-benzothiazol-2-yl)-5-(2-phenylcyclopropyl)-1H-pyrazol-3-amine	IC50	2100.0 [1]
	4-(1,3-Benzothiazol-2-yl)-3-N-(2-methoxyethyl)-1H-pyrazole-3,5-diamine	IC50	700.0 [1]
	4-(6-Bromobenzothiazol-2-YL)-5-methyl-2H-pyrazol-3-ylamine	IC50	400.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase ILK-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-ilk-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Serine/threonine-protein kinase ILK-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-ilk-1-inhibitors-ic50-ki.
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