Serine/threonine-protein kinase PAK 1/PAK 2/PAK 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-(1H-indol-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	120.0 [1]
	4-N-[5-[(1R,2S)-2-Fluorocyclopropyl]-1H-pyrazol-3-yl]-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	72.0 [1]
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)propyl]pyrimidine-2,4-diamine	IC50	180.0 [1]
	2-N-[(1S)-1-(6-Chloro-1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine	IC50	190.0 [1]
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	51.0 [1]
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-(6-fluoro-1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	57.0 [1]
	4-N-[5-[(1R,2R)-2-Fluorocyclopropyl]-1H-pyrazol-3-yl]-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	810.0 [1]
	2-N-[(1S)-1-(3-Chloro-1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine	IC50	160.0 [1]
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-[(1S)-1-(1H-pyrrolo[2,3-c]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	68.0 [1]
	4-N-[5-(3,3-Difluorocyclobutyl)-1H-pyrazol-3-yl]-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	250.0 [1]
	4-N-[5-[(1S,2S)-2-Fluorocyclopropyl]-1H-pyrazol-3-yl]-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	270.0 [1]
	4-N-[5-[(1S,2R)-2-Fluorocyclopropyl]-1H-pyrazol-3-yl]-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	92.0 [1]
	4-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-N-methyl-2-N-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine	IC50	240.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 13 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase PAK 1/PAK 2/PAK 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-pak-1-pak-2-pak-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Serine/threonine-protein kinase PAK 1/PAK 2/PAK 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-pak-1-pak-2-pak-3-inhibitors-ic50-ki.
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