Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol	IC50	110.0 [1]
	CID 71458575	IC50	0.11 [1]
	N-(3-Chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine	IC50	280.0 [1]
	4-({4-[3-(Piperidin-1-Ylcarbonyl)phenyl]pyrimidin-2-Yl}amino)benzenesulfonamide	IC50	450.0 [1]
	4-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide	IC50	370.0 [1]
	1-Methyl-3-[4-[4-[2-(3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]urea	IC50	0.05 [1]
	N-(3-Methoxyphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine	IC50	1100.0 [1]
	1-Methyl-3-[4-[4-[2-(4-methyl-3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]urea	IC50	0.05 [1]
	1-Methyl-3-[4-[4-[2-[4-methyl-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]urea	IC50	0.05 [1]
	3-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide	IC50	11.0 [1]
	4-(2-Morpholin-4-ylpyridin-4-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine	IC50	250.0 [1]
	3-[[4-(2-Morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzonitrile	IC50	80.0 [1]
	1-[4-[4-[2-[3-(Diethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea	IC50	0.2 [1]
	3-[[4-[2-(4-Methylpiperazin-1-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide	IC50	310.0 [1]
	3-[[4-(2-Piperidin-1-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide	IC50	3.0 [1]
	1-[4-[4-[2-[3-(Diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea	IC50	0.2 [1]
	3-[[4-[2-(3-Hydroxypropylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide	IC50	22.0 [1]
	N-(4-Chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine	IC50	1000.0 [1]
	4-(2-Morpholin-4-ylpyridin-4-yl)-N-phenylpyrimidin-2-amine	IC50	1500.0 [1]
	3-[[4-[2-(Diethylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide	IC50	3.0 [1]
	3-[[4-[2-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide	IC50	25.0 [1]
	1-Methyl-3-[4-[4-[2-[3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]urea	IC50	0.1 [1]
	1-[4-[4-[2-[3-(Dimethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea	IC50	0.05 [1]
	3-[[4-[2-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide	IC50	6.0 [1]
	1-[4-[4-[2-[4-Chloro-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea	IC50	0.05 [1]
	1-[4-[4-[2-[4-Chloro-3-(dimethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea	IC50	0.05 [1]
	N-(3-Methylphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine	IC50	330.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 27 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-smg1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Serine/threonine-protein kinase SMG1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serine-threonine-protein-kinase-smg1-inhibitors-ic50-ki.
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