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Serotonin 7 (5-HT7) receptor Inhibitors (IC50, Ki)
Structure
Compound Name
Standard Type
Standard Values (in nM)
(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenolIC500.9 [1], 3.71 [2]
ClozapineKi12.59 [1], 48.0 [2]
SerotoninIC501.5 [1]
MethiothepinIC501.5 [1], 3.1 [2], 21.0 [3]
MethiothepinKi0.9 [1], 1.0 [2], 1.7 [3], 3.7 [4]

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References
This online resource may be cited as follows
MLA
"Quest Database™ Serotonin 7 (5-HT7) receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 6 Dec. 2025, https://www.aatbio.com/data-sets/serotonin-7-5-ht7-receptor-inhibitors-ic50-ki.
APA
AAT Bioquest, Inc. (2025, December 6). Quest Database™ Serotonin 7 (5-HT7) receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/serotonin-7-5-ht7-receptor-inhibitors-ic50-ki.
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