Short transient receptor potential channel 5 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	6-(4-Chlorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	15.7 [1], 168.0 [2]
	5-[(4-Chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methyl-6-[3-(trifluoromethoxy)phenoxy]thieno[2,3-d]pyrimidine-2,4-dione	IC50	1.0 [1], 584.0 [2]
	5-[(4-Chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methyl-6-[3-(trifluoromethoxy)phenyl]thieno[2,3-d]pyrimidine-2,4-dione	IC50	1.0 [1], 1.91 [2]
	6-(3-Chlorophenoxy)-5-[(4-chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methylthieno[2,3-d]pyrimidine-2,4-dione	IC50	1.0 [1], 117.0 [2]
	6-(4-Chlorophenyl)-5-[(4-chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methylthieno[2,3-d]pyrimidine-2,4-dione	IC50	1.84 [1], 242.0 [2]
	6-(3-Chlorophenyl)-5-[(4-chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methylfuro[2,3-d]pyrimidine-2,4-dione	IC50	1.0 [1], 134.0 [2]
	4-[(3S,4R)-1-(2,4-Dichlorophenyl)sulfonyl-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]oxy-2-fluorobenzonitrile	IC50	10000.0 [1]
	3-(3-Hydroxypropyl)-1,5-dimethyl-6-naphthalen-2-ylthieno[2,3-d]pyrimidine-2,4-dione	IC50	34.9 [1]
	3-(3-Hydroxypropyl)-1,5-dimethyl-6-[2-(trifluoromethoxy)phenyl]thieno[2,3-d]pyrimidine-2,4-dione	IC50	21.0 [1]
	6-(3,4-Dichlorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	27.0 [1]
	5-(1-Hydroxy-3-methylbutyl)-3-(3-hydroxypropyl)-1-methyl-6-[3-(trifluoromethoxy)phenyl]thieno[2,3-d]pyrimidine-2,4-dione	IC50	369.0 [1]
	5-[(4-Chlorophenyl)-hydroxymethyl]-3-(3-hydroxypropyl)-1-methyl-6-[3-(trifluoromethoxy)phenoxy]thieno[2,3-d]pyrimidine-2,4-dione	IC50	194.0 [1]
	6-(3,4-Difluorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	112.0 [1]
	6-(3-Fluorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	27.0 [1]
	6-(3-Chlorophenyl)-5-[(4-chlorophenyl)methyl]-1,3-bis(3-hydroxypropyl)furo[2,3-d]pyrimidine-2,4-dione	IC50	4330.0 [1]
	6-(5-Chloropyridin-3-yl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	1700.0 [1]
	6-(3-Chlorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	226.0 [1]
	3-(3-Hydroxypropyl)-1-methyl-5-(3-methylbutyl)-6-[3-(trifluoromethoxy)phenyl]thieno[2,3-d]pyrimidine-2,4-dione	IC50	340.0 [1]
	6-(2-Chlorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	27.0 [1]
	6-(2,3-Dichlorophenyl)-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	31.6 [1]
	6-(3-Chlorophenyl)-5-[(4-chlorophenyl)-hydroxymethyl]-3-(3-hydroxypropyl)-1-methylthieno[2,3-d]pyrimidine-2,4-dione	IC50	55.0 [1]
	6-(3-Chlorophenyl)-5-[(4-chlorophenyl)methyl]-3-(3-hydroxypropyl)-1-methylthieno[2,3-d]pyrimidine-2,4-dione	IC50	27.0 [1]
	3-(3-Hydroxypropyl)-1,5-dimethyl-6-[3-(trifluoromethoxy)phenyl]thieno[2,3-d]pyrimidine-2,4-dione	IC50	82.2 [1]
	6-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-(3-hydroxypropyl)-1,5-dimethylthieno[2,3-d]pyrimidine-2,4-dione	IC50	27.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 24 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Short transient receptor potential channel 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/short-transient-receptor-potential-channel-5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Short transient receptor potential channel 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/short-transient-receptor-potential-channel-5-inhibitors-ic50-ki.
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