Signal transducer and activator of transcription 5B Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Sodium	IC50	10400.0 [1]
	NF449 octasodium salt	IC50	2500.0 [1]
	4-[(4-Cyclohexylphenyl)methyl-[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	25000.0 [1]
	4-[(4-Cyclohexylphenyl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	2800.0 [1]
	[4-[[[2-[6-(Phenylcarbamoyl)naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	154.0 [1]
	4-[[2-[(4-Chlorophenyl)sulfonyl-methylamino]acetyl]-[(4-cyclohexylphenyl)methyl]amino]-2-hydroxybenzoic acid	Ki	7900.0 [1]
	4-[(4-Cyclohexylphenyl)methyl-[2-[methyl-(4-phenylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	4100.0 [1]
	4-[[4-[1-(4-Cyanophenyl)sulfonylpiperidin-4-yl]phenyl]methyl-[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	7300.0 [1]
	4-[(4-Cyclohexylphenyl)methyl-[2-[(4-methylphenyl)sulfonyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]amino]-2-hydroxybenzoic acid	Ki	3400.0 [1]
	4-[[4-[4-(4-Carbamoylphenyl)phenyl]phenyl]methyl-[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	4800.0 [1]
	4-[[2-[(4-Chlorophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-[(3,5-ditert-butylphenyl)methyl]amino]-2-hydroxybenzoic acid	Ki	145.8 [1]
	2-Hydroxy-4-[(1-methylimidazol-2-yl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]benzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-(naphthalen-2-ylmethyl)amino]benzoic acid	Ki	12360.0 [1]
	4-[Benzyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]-(thiophen-2-ylmethyl)amino]benzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[(4-methylphenyl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]benzoic acid	Ki	60000.0 [1]
	4-[(3,5-Ditert-butylphenyl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	4770.0 [1]
	4-[(4-Tert-butylphenyl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	4-[(4-Tert-butylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	4-[(4-Fluorophenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	4-[(3,5-Ditert-butylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	11500.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-(oxolan-2-ylmethyl)amino]benzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]-(oxolan-2-ylmethyl)amino]benzoic acid	Ki	60000.0 [1]
	4-[Cyclopropylmethyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[(1-methylimidazol-2-yl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]benzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]-(naphthalen-2-ylmethyl)amino]benzoic acid	Ki	6620.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-(thiophen-2-ylmethyl)amino]benzoic acid	Ki	60000.0 [1]
	4-[Cyclopropylmethyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	4-[1-Bicyclo[2.2.1]heptanylmethyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	4-[(4-Fluorophenyl)methyl-[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetyl]-[(2,3,4,5,6-pentafluorophenyl)methyl]amino]benzoic acid	Ki	60000.0 [1]
	4-[1-Bicyclo[2.2.1]heptanylmethyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-[(4-methylphenyl)methyl]amino]benzoic acid	Ki	60000.0 [1]
	4-[Benzyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	60000.0 [1]
	2-Hydroxy-4-[[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-[(2,3,4,5,6-pentafluorophenyl)methyl]amino]benzoic acid	Ki	60000.0 [1]
	[4-[[[2-[4-[(4-Chlorophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	330.0 [1]
	[4-[[[2-[4-[(4-Bromophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	390.0 [1]
	[4-[[[2-[4-[(4-Fluorophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	350.0 [1]
	[4-[[[2-[4-[(3-Fluorophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	620.0 [1]
	[4-[[[2-[4-[(3-Bromophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	660.0 [1]
	[4-[[[2-[4-[(3-Chlorophenyl)carbamoyl]phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	460.0 [1]
	[4-[[[2-[4-(Phenylcarbamoyl)phenoxy]acetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	280.0 [1]
	[4-[[[2-[6-[(3-Bromophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	290.0 [1]
	[4-[[[2-[6-[(4-Chlorophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	270.0 [1]
	[4-[[[2-[6-[(4-Bromophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	240.0 [1]
	[4-[[[2-[6-[(3-Fluorophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	234.0 [1]
	[4-[[[2-[6-[(3-Chlorophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	260.0 [1]
	[4-[[[2-[6-[(4-Fluorophenyl)carbamoyl]naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate	IC50	220.0 [1]
	2-Hydroxy-4-[[4-[4-(3-methoxycarbonylphenyl)phenyl]phenyl]methyl-[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]benzoic acid	Ki	3800.0 [1]
	4-[Benzyl-[2-[(4-methylphenyl)sulfonyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]amino]-2-hydroxybenzoic acid	Ki	8300.0 [1]
	4-[[4-[1-(4-Carbamoylphenyl)piperidin-4-yl]phenyl]methyl-[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid	Ki	10100.0 [1]
	Hexasodium;8-[[3-[[3-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]benzoyl]amino]naphthalene-1,3,5-trisulfonate;hydrate	IC50	12700.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 52 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Signal transducer and activator of transcription 5B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/signal-transducer-and-activator-of-transcription-5b-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Signal transducer and activator of transcription 5B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/signal-transducer-and-activator-of-transcription-5b-inhibitors-ic50-ki.
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