Small conductance calcium-activated potassium channel protein 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3-[(1R,4S,7S,13S,16S,19S,22S,25S,28R,31S,34S,37S,40R,47S,50R)-50-Amino-40-[[(2S)-5-amino-1-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]carbamoyl]-4-(4-aminobutyl)-47-(2-amino-2-oxoethyl)-34,37-bis(3-carbamimidamidopropyl)-19-[(1R)-1-hydroxyethyl]-7,22,31-trimethyl-25-(2-methylpropyl)-2,5,8,14,17,20,23,26,29,32,35,38,46,49-tetradecaoxo-42,43,52,53-tetrathia-3,6,9,15,18,21,24,27,30,33,36,39,45,48-tetradecazatricyclo[26.16.10.09,13]tetrapentacontan-16-yl]propanoic acid	IC50	0.06 [1], 0.17 [2]
	Pyridin-2-yl-(4-pyridin-2-yl-thiazol-2-yl)-amine	IC50	25.0 [1], 290.0 [2], 543.0 [3]
	N-(4-Methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine	IC50	4.0 [1], 56.0 [2], 59.0 [3]
	Dequalinium chloride	IC50	1300.0 [1], 2000.0 [2]
	5-Chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	350.0 [1], 580.0 [2]
	N-Benzyl-5-chloropyrazolo[1,5-a]pyrimidin-7-amine	IC50	1100.0 [1], 1600.0 [2]
	2-Methyl-1-[[3-[(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)methyl]phenyl]methyl]-8-propan-2-ylisoquinolin-2-ium	IC50	2970.0 [1]
	2-Methyl-1-[[3-[(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)methyl]phenyl]methyl]-8-propan-2-ylisoquinolin-2-ium	Ki	46.0 [1]
	N-Phenyl-4-(pyridin-2-yl)thiazol-2-amine	IC50	30000.0 [1]
	N-(4-(Pyridin-3-yl)thiazol-2-yl)pyridin-2-amine	IC50	30000.0 [1]
	N-Pyridin-2-yl-4-pyridin-4-yl-1,3-thiazol-2-amine	IC50	30000.0 [1]
	5-Chloro-N-(2-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	19100.0 [1]
	5-Chloro-N-(4-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	N,4-Diphenyl-1,3-thiazol-2-amine	IC50	30000.0 [1]
	2,4-Bis(2-pyridyl)thiazole	IC50	30000.0 [1]
	2,9-Diaza-17,23-diazoniahexacyclo[21.6.2.24,7.210,17.011,16.024,29]pentatriaconta-1(30),4,6,10(33),11,13,15,17(32),23(31),24,26,28,34-tridecaene	IC50	60.0 [1]
	(1S)-1-[3-[(1S)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]propyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;dihydrochloride	IC50	3000.0 [1]
	N-(4-(Pyridin-2-yl)thiazol-2-yl)pyrimidin-2-amine	IC50	30000.0 [1]
	N-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-pyridin-2-yl-1,3-thiazol-2-amine	IC50	30000.0 [1]
	5-Iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-amine	IC50	30000.0 [1]
	N-(4-(Pyridin-2-yl)thiazol-2-yl)pyridin-4-amine	IC50	30000.0 [1]
	2-(2-(Pyridin-2-ylmethyl)thiazol-4-yl)pyridine	IC50	30000.0 [1]
	5-Chloro-N-(2-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	14600.0 [1]
	5-Chloro-N-(2-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(2-methoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	15900.0 [1]
	5-Chloro-N-(2-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	10000.0 [1]
	5-Chloro-N-(3-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	5200.0 [1]
	5-Chloro-N-(3-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	10700.0 [1]
	5-Chloro-N-(3-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	14600.0 [1]
	5-Chloro-N-(3-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	11000.0 [1]
	5-Chloro-N-(3-nitrobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	7900.0 [1]
	5-Chloro-N-(4-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(4-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(4-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	15400.0 [1]
	5-Chloro-N-(4-nitrobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(4-phenoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	5-Chloro-N-(3,5-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	30000.0 [1]
	(R)-5-Chloro-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	1000.0 [1]
	5-Chloro-N-(1,2-diphenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine	IC50	7500.0 [1]
	2,10-Diaza-18,24-diazoniahexacyclo[22.6.2.211,18.14,8.012,17.025,30]pentatriaconta-1(31),4(35),5,7,11(34),12,14,16,18(33),24(32),25,27,29-tridecaene	IC50	31.0 [1]
	2-Methyl-1-[[4-[(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)methyl]phenyl]methyl]-8-propan-2-ylisoquinolin-2-ium	Ki	1268.0 [1]
	2-Methyl-1-[3-(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)propyl]-8-propan-2-ylisoquinolin-2-ium	Ki	837.0 [1]
	2-Methyl-1-[5-(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)pentyl]-8-propan-2-ylisoquinolin-2-ium	Ki	575.0 [1]
	2-Methyl-1-[4-(2-methyl-8-propan-2-ylisoquinolin-2-ium-1-yl)butyl]-8-propan-2-ylisoquinolin-2-ium	Ki	214.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 45 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Small conductance calcium-activated potassium channel protein 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/small-conductance-calcium-activated-potassium-channel-protein-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Small conductance calcium-activated potassium channel protein 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/small-conductance-calcium-activated-potassium-channel-protein-3-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan