Sodium-dependent proline transporter Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Biphenyl-4-yl-(4-phenyl-piperazin-1-yl)-methanone	IC50	1480.0 [1]
	Biphenyl-4-yl-[4-(4-fluoro-phenyl)-piperazin-1-yl]-methanone	IC50	3440.0 [1]
	4-Phenylphenyl 4-pyrimidin-2-ylpiperazinyl ketone	IC50	280.0 [1]
	4-Phenylphenyl 4-(2-pyridyl)piperazinyl ketone	IC50	160.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(3-pyrimidin-2-yl-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone	IC50	18.0 [1]
	(3-Phenylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	1880.0 [1]
	[4-(5-Chlorothiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	150.0 [1]
	[4-(4-Methylthiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	34.0 [1]
	[4-(5-Methylthiophen-2-yl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	61.0 [1]
	[4-(2-Phenylethoxy)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	1020.0 [1]
	[4-(Benzylamino)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	870.0 [1]
	2-Phenyl-N-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]acetamide	IC50	10000.0 [1]
	Benzyl N-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]carbamate	IC50	10000.0 [1]
	(2-Tert-butyl-4-pyrimidin-2-ylpiperazin-1-yl)-[4-(3-chlorophenyl)phenyl]methanone	IC50	700.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(2,2-dimethyl-4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	53.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(2,6-dimethyl-4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	24.0 [1]
	[4-(3-Chlorophenyl)phenyl]-[2-(hydroxymethyl)-4-pyrimidin-2-ylpiperazin-1-yl]methanone	IC50	76.0 [1]
	1-[4-(3-Chlorophenyl)benzoyl]-4-pyrimidin-2-ylpiperazine-2-carboxylic acid	IC50	128.0 [1]
	1-[4-(3-Chlorophenyl)benzoyl]-N,N-dimethyl-4-pyrimidin-2-ylpiperazine-2-carboxamide	IC50	392.0 [1]
	[4-(4-Chlorophenyl)phenyl]-[(2R)-2-methyl-4-pyrimidin-2-ylpiperazin-1-yl]methanone	IC50	57.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(4-pyrimidin-2-yl-1,4-diazepan-1-yl)methanone	IC50	89.0 [1]
	4-(3-Chlorophenyl)-N-methyl-N-[2-[methyl(pyrimidin-2-yl)amino]ethyl]benzamide	IC50	586.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(5-pyrimidin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl)methanone	IC50	1340.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(8-pyrimidin-2-yl-3,8-diazabicyclo[3.2.1]octan-3-yl)methanone	IC50	27.0 [1]
	4-(4-Chlorophenyl)piperazinyl 4-phenylphenyl ketone	IC50	10000.0 [1]
	[4-(4-Fluorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	260.0 [1]
	(3-Methyl-4-pyrimidin-2-ylpiperazin-1-yl)-(4-phenylphenyl)methanone	IC50	477.0 [1]
	[4-(4-Methylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	34.0 [1]
	[4-(3-Chlorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	36.0 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[3-(trifluoromethyl)phenyl]phenyl]methanone	IC50	71.0 [1]
	[4-(4-Ethylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	77.0 [1]
	[4-(4-Methylpyrimidin-2-yl)piperazin-1-yl]-(4-phenylphenyl)methanone	IC50	270.0 [1]
	(4-Pyridin-2-ylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	7080.0 [1]
	(4-Phenylphenyl)-(4-pyrazin-2-ylpiperazin-1-yl)methanone	IC50	1300.0 [1]
	[4-(4-Methoxyphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	230.0 [1]
	4-[4-(4-Pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]benzonitrile	IC50	190.0 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[2-(trifluoromethyl)phenyl]phenyl]methanone	IC50	1260.0 [1]
	[4-(4-Chlorophenyl)phenyl]-[(2S)-2-methyl-4-pyrimidin-2-ylpiperazin-1-yl]methanone	IC50	21.0 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[4-(trifluoromethyl)phenyl]phenyl]methanone	IC50	76.0 [1]
	[4-(4-Chlorophenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	52.0 [1]
	[4-(2-Methylphenyl)phenyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	653.0 [1]
	(4-Phenylphenyl)-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone	IC50	2180.0 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-[3-(trifluoromethoxy)phenyl]phenyl]methanone	IC50	73.0 [1]
	(4-Phenylphenyl)-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanone	IC50	146.0 [1]
	3-[4-(4-Pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]benzonitrile	IC50	190.0 [1]
	(4-Cyclohexylphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	7010.0 [1]
	2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine	IC50	1950.0 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-(4-pyrrol-1-ylphenyl)methanone	IC50	2230.0 [1]
	Phenyl-[4-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]methanone	IC50	2700.0 [1]
	2-{4-[4-(1H-Imidazol-1-yl)benzoyl]piperazin-1-yl}pyrimidine	IC50	10000.0 [1]
	2-(4-{[1,1'-Biphenyl]-2-carbonyl}piperazin-1-yl)pyrimidine	IC50	6010.0 [1]
	(3'-Chloro-biphenyl-4-yl)-(5-Pyrimidin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone	IC50	36.0 [1]
	[1,1'-Biphenyl]-4-yl(4-(pyridazin-3-yl)piperazin-1-yl)methanone	IC50	5000.0 [1]
	(4-Phenylmethoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	IC50	270.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 54 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Sodium-dependent proline transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/sodium-dependent-proline-transporter-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Sodium-dependent proline transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sodium-dependent-proline-transporter-inhibitors-ic50-ki.
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