Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-[[3-[2-(4-Fluorophenyl)ethoxy]phenyl]methyl]-2-(4-methoxyphenyl)-N-(pyridin-4-ylmethyl)acetamide	IC50	18200.0 [1]
	4-Methoxy-N-[[3-[(3-methoxyphenyl)methoxy]phenyl]methyl]-N-(pyridin-4-ylmethyl)benzamide	IC50	11000.0 [1]
	Chembl4164091	IC50	20000.0 [1]
	Chembl4171968	IC50	1700.0 [1]
	4-[[2-(4-Chlorophenyl)-6-(2-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	6.0 [1]
	(2S)-3-(4-Fluorophenyl)-2-[[2-(3-hydroxyphenyl)acetyl]amino]-N-[(1S)-1-phenylethyl]propanamide	IC50	195.0 [1]
	(2S)-3-(2-Bromophenyl)-2-[[2-(4-methoxyphenyl)acetyl]amino]-N-[(1S)-1-phenylethyl]propanamide	IC50	90.0 [1]
	4-[[2-(4-Chlorophenyl)-6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	10000.0 [1]
	4-[[6-(2-Chlorophenyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	6.0 [1]
	4-[[2-(4-Chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	6.0 [1]
	4-[[2-(2,4-Dichlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	6.0 [1]
	4-[[2-(4-Chlorophenyl)-5-methyl-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]morpholine	IC50	6.0 [1]
	4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]morpholine	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	2-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]benzonitrile	IC50	6.0 [1]
	4-[[2-(4-Chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]morpholine	IC50	6.0 [1]
	N-[2-(4-Chlorophenyl)-3-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	[4-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyridin-4-ylmethanone	IC50	6.0 [1]
	1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyrazin-2-ylmethanone	IC50	6.0 [1]
	[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-pyridazin-4-ylmethanone	IC50	6.0 [1]
	[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-(oxan-4-yl)methanone	IC50	6.0 [1]
	[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-(1,3-thiazol-4-yl)methanone	IC50	6.0 [1]
	N-[2-(4-Chlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(4-Chlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(4-Chlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-methoxyethanone	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]ethanesulfonamide	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylethanesulfonamide	IC50	6.0 [1]
	1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-hydroxy-2-methylpropan-1-one	IC50	6.0 [1]
	1-[4-[[6-Cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl]methyl]piperazin-1-yl]-2-hydroxyethanone	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-(1,1-dioxothiazinan-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxetane-3-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-methoxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	1-[4-[[2-(2,4-Dichlorophenyl)-6-(1,1-dioxo-1,2-thiazolidin-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylpropane-2-sulfonamide	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-methylpropane-1-sulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-(6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-7-ylmethyl)imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)-N,N-dimethylimidazo[1,2-a]pyridine-6-sulfonamide	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-ethylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[(3-oxopiperazin-1-yl)methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(4-fluorobenzoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(4-fluorobenzoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(1-methylpyrazole-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[(4-hydroxypiperazin-1-yl)methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	4-[[2-(2,4-Dichlorophenyl)-6-propan-2-ylimidazo[1,2-a]pyrazin-3-yl]methyl]morpholine	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(difluoromethyl)methanesulfonamide	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(difluoromethyl)methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxane-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxyacetyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-methylsulfanylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-propan-2-ylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[(6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl)methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-ethylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	N-[3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-propan-2-ylmethanesulfonamide	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(pyridazine-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]-N-methylmethanesulfonamide	IC50	6.0 [1]
	1-[4-[[2-(4-Chlorophenyl)-6-methylsulfonylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]ethanone	IC50	6.0 [1]
	2-[[2-(4-Chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl]methyl]-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one	IC50	6.0 [1]
	N-[2-(2,4-Dichlorophenyl)-3-[[4-(oxane-4-carbonyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridin-6-yl]methanesulfonamide	IC50	6.0 [1]
	3-[(4-Acetylpiperazin-1-yl)methyl]-2-(4-chlorophenyl)-N-methylimidazo[1,2-a]pyridine-6-sulfonamide	IC50	6.0 [1]
	[4-[[2-(4-Chlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-(3-fluorophenyl)methanone	IC50	6.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 69 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Solute carrier family 2, facilitated glucose transporter member 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/solute-carrier-family-2-facilitated-glucose-transporter-member-4-inhibitors-ic50-ki.
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