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Sphingosine 1-phosphate receptor Edg-1 Inhibitors (IC50, Ki)
Structure
Compound Name
Standard Type
Standard Values (in nM)
Sphingosine 1-phosphateIC500.16 [1], 0.47 [2], 0.67 [3], 0.78 [4], 1.4 [5]
FTY720 phosphateIC500.01 [1], 0.28 [2]
\n\n- Open Babel Depiction\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nN\nO\nS\nF\nF\nF\nO\nHO\n\n\n\n\n1-(4-((4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acidIC501.2 [1]
Merck SIP AgonistIC500.6 [1]
3-(Tetradecylamino)propylphosphonic acidIC502.3 [1], 3.7 [2]

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References
This online resource may be cited as follows
MLA
"Quest Database™ Sphingosine 1-phosphate receptor Edg-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 4 Jan. 2026, https://www.aatbio.com/data-sets/sphingosine-1-phosphate-receptor-edg-1-inhibitors-ic50-ki.
APA
AAT Bioquest, Inc. (2026, January 4). Quest Database™ Sphingosine 1-phosphate receptor Edg-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/sphingosine-1-phosphate-receptor-edg-1-inhibitors-ic50-ki.
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