Synaptic vesicular amine transporter Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Serotonin	IC50	1430.0 [1]
	Serotonin	Ki	2290.0 [1], 7690.0 [2], 640000.0 [3]
	Reserpine	IC50	13.2 [1]
	Reserpine	Ki	5.26 [1], 410.0 [2], 630.0 [3]
	DL-Methamphetamine	IC50	3620.0 [1]
	DL-Methamphetamine	Ki	6400.0 [1], 24500.0 [2], 346000.0 [3]
	Ketanserin	IC50	180.0 [1]
	Ketanserin	Ki	77.0 [1], 353.0 [2], 1190.0 [3]
	Lobeline	IC50	4200.0 [1]
	Lobeline	Ki	1840.0 [1], 1950.0 [2], 10000.0 [3]
	Dihydrotetrabenazine	IC50	28.1 [1]
	Dihydrotetrabenazine	Ki	70.0 [1], 152.0 [2], 10000.0 [3]
	2H-Benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-	IC50	154.0 [1]
	2H-Benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-	Ki	64.0 [1], 83.0 [2], 1932.0 [3]
	Ethyl (3S,4R)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	IC50	85.5 [1]
	Ethyl (3S,4R)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	Ki	176.0 [1], 750.0 [2], 1150.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-thiophen-2-ylpiperidine-3-carboxylate	IC50	101.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-thiophen-2-ylpiperidine-3-carboxylate	Ki	450.0 [1], 900.0 [2], 6160.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	IC50	39.4 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	Ki	74.0 [1], 161.0 [2], 7400.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-phenylpiperidine-3-carboxylate	IC50	19.7 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-phenylpiperidine-3-carboxylate	Ki	70.0 [1], 287.0 [2], 7700.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-methylphenyl)piperidine-3-carboxylate	IC50	2700.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-methylphenyl)piperidine-3-carboxylate	Ki	452.0 [1], 9100.0 [2], 10000.0 [3]
	Ethyl (3S,4S)-4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate	IC50	142.0 [1]
	Ethyl (3S,4S)-4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate	Ki	652.0 [1], 700.0 [2], 7900.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylate	IC50	2900.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylate	Ki	720.0 [1], 10000.0 [2]
	Ethyl (3S,4S)-4-[4-(dimethylamino)phenyl]-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate	IC50	5800.0 [1]
	Ethyl (3S,4S)-4-[4-(dimethylamino)phenyl]-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate	Ki	1960.0 [1], 10000.0 [2]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperidine-3-carboxylate	IC50	125.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperidine-3-carboxylate	Ki	350.0 [1], 990.0 [2], 10000.0 [3]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-phenylphenyl)piperidine-3-carboxylate	IC50	10000.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-phenylphenyl)piperidine-3-carboxylate	Ki	3770.0 [1], 10000.0 [2]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-ethoxycarbonylphenyl)piperidine-3-carboxylate	IC50	10000.0 [1]
	Ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-ethoxycarbonylphenyl)piperidine-3-carboxylate	Ki	1660.0 [1], 10000.0 [2]
	Ethyl 1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	IC50	51.1 [1]
	Ethyl 1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate	Ki	179.0 [1], 290.0 [2], 10000.0 [3]
	Lobelin	Ki	2760.0 [1]
	Florbenazine	Ki	0.1 [1]
	Lobelane	Ki	970.0 [1]
	10S-Hydroxylobel-7-ene	Ki	6060.0 [1]
	(2R,6S)-1-Methyl-2,6-bis-(2-naphthalen-1-yl-ethyl)-piperidine	Ki	630.0 [1]
	2-[4-[4-(7-(111C)Methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione	Ki	10000.0 [1]
	8R-Hydroxylobel-9-ene	Ki	5160.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 45 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Synaptic vesicular amine transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/synaptic-vesicular-amine-transporter-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Synaptic vesicular amine transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/synaptic-vesicular-amine-transporter-inhibitors-ic50-ki.
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