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Taste receptor type 2 member 14 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-[(N-Benzyl4-chlorobenzenesulfonamido)methyl]benzoic acidIC50394.0 [1]
4-(Dibenzylsulfamoyl)benzoic AcidIC507740.0 [1]
7-Ethyl-1,3-dimethyl-5-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanylpyrimido[4,5-d]pyrimidine-2,4-dioneIC50721.0 [1]
N-(3-Fluoro-2-methylphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamideIC50935.0 [1]
N-(1,3-Benzodioxol-5-yl)-1,3-dimethyl-2,4-dioxoquinazoline-6-sulfonamideIC50264.0 [1]
4-[((4-Methoxybenzyl){[(2-methoxyphenyl)amino]carbonothioyl}amino)methyl]cyclohexanecarboxylic acidIC508852.0 [1]
Ethyl 4-[2-(7-ethyl-1,3-dimethyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanylacetyl]piperazine-1-carboxylateIC50763.0 [1]
N-(4-Fluorophenyl)-1,4,7-trimethyl-2,3-dioxoquinoxaline-6-sulfonamideIC5012623.0 [1]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dimethyl-2,3-dioxoquinoxaline-6-sulfonamideIC507710.0 [1]
4-[[(3-Chloro-4-methylphenyl)carbamothioyl-[(4-methoxyphenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acidIC506136.0 [1]
1,3,7-Trimethyl-5-((2-morpholino-2-oxoethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dioneIC501006.0 [1]
4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamideIC5039810.72 [1]
4-Diisobutylsulfamoyl-benzoic acidIC5015000.0 [1]
1,3-Dimethyl-N-(2-methylphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamideIC501726.0 [1]
2-[(1,4-Dimethyl-2,3-dioxoquinoxalin-6-yl)sulfonyl-methylamino]-N-ethyl-N-(3-methylphenyl)acetamideIC5014926.0 [1]
Ethyl 4-({benzyl[(4-bromophenyl)sulfonyl]amino}methyl)cyclohexanecarboxylateIC502344.0 [1]
Ethyl 4-({benzyl[(4-chlorophenyl)sulfonyl]amino}methyl)cyclohexanecarboxylateIC50672.0 [1]
4-[Cyclohexylmethyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC503470.0 [1]
4-[Benzyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC50220.0 [1]
N-Methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamideIC506234.0 [1]
4-[(4-Ethoxyphenyl)methyl-(furan-2-ylmethyl)sulfamoyl]benzoic acidIC503000.0 [1]
(Z)-3-(5-(2,5-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acidIC502750.0 [1]
N-(2-Cyano-3,5-dimethylphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamideIC501946.0 [1]
N-Cyclohexyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamideIC507239.0 [1]
Ethyl 4-{[{[4-(acetylamino)phenyl]sulfonyl}(benzyl)amino]methyl}cyclohexanecarboxylateIC50334.0 [1]
4-[[(4-Fluorophenyl)methyl-(4-methoxyphenyl)sulfonylamino]methyl]cyclohexane-1-carboxylic acidIC5092.0 [1]
4-[[(4-Fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]methyl]cyclohexane-1-carboxylic acidIC5083.0 [1]
4-[Furan-2-ylmethyl-[(3-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC5010000.0 [1]
4-[Furan-2-ylmethyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC50590.0 [1]
4-[Benzyl-[(4-fluorophenyl)methyl]sulfamoyl]benzoic acidIC508283.0 [1]
4-[Benzyl(furan-2-ylmethyl)sulfamoyl]benzoic acidIC504600.0 [1]
4-[[Benzenesulfonyl-[(4-fluorophenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acidIC50240.0 [1]
4-[[(4-Acetamidophenyl)sulfonyl-benzylamino]methyl]cyclohexane-1-carboxylic acidIC501619.0 [1]
4-[(4-Methoxyphenyl)methyl-propylsulfamoyl]benzoic acidIC503750.0 [1]
4-[(3-Chlorophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC501880.0 [1]
4-[[Benzyl-(4-methylphenyl)sulfonylamino]methyl]cyclohexane-1-carboxylic acidIC5014.0 [1]
4-[(4-Fluorophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC508283.0 [1]
4-[Furan-2-ylmethyl-[(4-propoxyphenyl)methyl]sulfamoyl]benzoic acidIC502500.0 [1]
N-Ethyl-N-methyl-2-(1,3,7-trimethyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanylacetamideIC50861.0 [1]
4-[[(4-Hydroxyphenyl)sulfonyl-[(4-methoxyphenyl)methyl]amino]methyl]benzoic acidIC503430.0 [1]
4-[[(4-Hydroxyphenyl)sulfonyl-[(3-methoxyphenyl)methyl]amino]methyl]benzoic acidIC50188.0 [1]
4-[[(4-Hydroxyphenyl)sulfonyl-[(2-methoxyphenyl)methyl]amino]methyl]benzoic acidIC502560.0 [1]
4-[(3,4-Dimethoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC501470.0 [1]
4-[Benzyl-[(3,4-dimethoxyphenyl)methyl]sulfamoyl]benzoic acidIC50678.0 [1]
4-[(3-Methoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC502460.0 [1]
4-[(2-Cyanophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC504610.0 [1]
4-[[(4-Chloro-3-methylphenyl)carbamothioyl-[(2-methylphenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acidIC504872.0 [1]
1,3,7-Trimethyl-5-((2-oxo-2-(piperidin-1-yl)ethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dioneIC50292.0 [1]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-dimethyl-2,4-dioxoquinazoline-6-sulfonamideIC50706.0 [1]
N-(2,3-Dimethylquinoxalin-6-yl)-1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamideIC506332.0 [1]
1,4-Dimethyl-2,3-dioxo-N-[4-(pyridin-2-ylmethyl)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamideIC506140.0 [1]
Ethyl 4-({(2-chlorobenzyl)[(4-methylphenyl)sulfonyl]amino}methyl)cyclohexanecarboxylateIC502816.0 [1]
Ethyl 4-[[(3-bromophenyl)methyl-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]methyl]cyclohexane-1-carboxylateIC502567.0 [1]
4-[Ethyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC5010000.0 [1]
4-[Benzyl-[(2,4,6-trimethoxyphenyl)methyl]sulfamoyl]benzoic acidIC5010760.0 [1]
4-[(4-Methoxyphenyl)methyl-(2-phenylethyl)sulfamoyl]benzoic acidIC504580.0 [1]
4-[Bis[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC504140.0 [1]
4-[[(4-Fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]methyl]benzoic acidIC5054.0 [1]
4-[[(3-Fluorophenyl)methyl-(4-hydroxyphenyl)sulfonylamino]methyl]benzoic acidIC50459.0 [1]
N-Benzyl-N-[(4-methoxyphenyl)methyl]-4-(2H-tetrazol-5-yl)benzenesulfonamideIC503670.0 [1]
4-[(2-Methoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC502943.0 [1]
4-[(4-Methoxyphenyl)methyl-[(2-methylphenyl)methyl]sulfamoyl]benzoic acidIC505316.0 [1]
4-[(3,5-Dimethoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC5012141.0 [1]
4-[(2-Chlorophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC507044.0 [1]
4-[Benzyl-[(4-methylphenyl)methyl]sulfamoyl]benzoic acidIC505394.0 [1]
4-[Benzyl-[(2-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC505061.0 [1]
4-[Benzyl-[(2-fluorophenyl)methyl]sulfamoyl]benzoic acidIC506164.0 [1]
4-[Benzyl-[(3-methylphenyl)methyl]sulfamoyl]benzoic acidIC502290.0 [1]
4-[Benzyl-[(3-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC505991.0 [1]
4-[Benzyl-[(4-chlorophenyl)methyl]sulfamoyl]benzoic acidIC503977.0 [1]
4-[Benzyl-[(4-methylsulfanylphenyl)methyl]sulfamoyl]benzoic acidIC502458.0 [1]
4-[Benzyl-[(3-fluorophenyl)methyl]sulfamoyl]benzoic acidIC502310.0 [1]
4-[Benzyl-[(2-methylphenyl)methyl]sulfamoyl]benzoic acidIC502926.0 [1]
4-[Benzyl-[(2-chlorophenyl)methyl]sulfamoyl]benzoic acidIC504486.0 [1]
4-[Benzyl-[(3-chlorophenyl)methyl]sulfamoyl]benzoic acidIC504286.0 [1]
4-[Benzyl-[(4-ethylphenyl)methyl]sulfamoyl]benzoic acidIC508580.0 [1]
4-[Benzyl-[(4-methoxy-3-methylphenyl)methyl]sulfamoyl]benzoic acidIC501995.0 [1]
4-[Benzyl-[(6-methoxypyridin-3-yl)methyl]sulfamoyl]benzoic acidIC503258.0 [1]
4-[Benzyl-[(4-cyanophenyl)methyl]sulfamoyl]benzoic acidIC501848.0 [1]
4-[Benzyl-[(2-cyanophenyl)methyl]sulfamoyl]benzoic acidIC504627.0 [1]
4-[1,3-Benzodioxol-5-ylmethyl(benzyl)sulfamoyl]benzoic acidIC502167.0 [1]
4-[(4-Methoxyphenyl)methyl-(1-phenylethyl)sulfamoyl]benzoic acidIC501397.0 [1]
4-[(4-Methoxyphenyl)methyl-(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]benzoic acidIC502415.0 [1]
4-[Benzyl-[(4-hydroxyphenyl)methyl]sulfamoyl]benzoic acidIC505207.0 [1]
4-[[Benzenesulfonyl-[(2-methoxyphenyl)methyl]amino]methyl]benzoic acidIC501294.0 [1]
4-[[Benzenesulfonyl-[(3-methoxyphenyl)methyl]amino]methyl]benzoic acidIC50345.0 [1]
4-[[Benzenesulfonyl-[(4-methoxyphenyl)methyl]amino]methyl]benzoic acidIC502219.0 [1]
4-[[Benzenesulfonyl-[(2-fluorophenyl)methyl]amino]methyl]benzoic acidIC50429.0 [1]
4-[[Benzenesulfonyl-[(3-fluorophenyl)methyl]amino]methyl]benzoic acidIC50406.0 [1]
4-[[Benzenesulfonyl-[(4-fluorophenyl)methyl]amino]methyl]benzoic acidIC50935.0 [1]
4-[[(4-Fluorophenyl)methyl-(4-hydroxyphenyl)sulfonylamino]methyl]benzoic acidIC504086.0 [1]
4-[[(4-Ethylphenyl)methyl-[(2-methylphenyl)carbamothioyl]amino]methyl]cyclohexane-1-carboxylic acidIC505018.0 [1]
N-Benzyl-3-methoxy-N-[(4-methoxyphenyl)methyl]benzenesulfonamideIC502219.0 [1]
4-[[(4-Cyanophenyl)methyl-(4-methylphenyl)sulfonylamino]methyl]cyclohexane-1-carboxylic acidIC50499.0 [1]
4-[[(3-Methoxyphenyl)methyl-(4-methylphenyl)sulfonylamino]methyl]cyclohexane-1-carboxylic acidIC5036.0 [1]
4-[(2,4-Difluorophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acidIC501255.0 [1]
4-[[3-(4-Methoxyphenyl)-3,4-dihydro-1H-isoquinolin-2-yl]sulfonyl]benzoic acidIC506267.0 [1]
4-[(6-Methoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC509616.0 [1]
4-[(7-Methoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC502879.0 [1]
4-[[Benzylsulfonyl-[(4-fluorophenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acidIC509570.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Taste receptor type 2 member 14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/taste-receptor-type-2-member-14-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Taste receptor type 2 member 14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/taste-receptor-type-2-member-14-inhibitors-ic50-ki.
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