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Telomerase reverse transcriptase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Homidium bromideIC502500.0 [1]
(E)-2-(3-(Naphthalen-2-yl)but-2-enamido)benzoic acidIC50280.0 [1]
TelomestatinIC5020.0 [1]
7,8,3',4'-TetrahydroxyflavoneIC50230.0 [1]
Braco-19IC5090.0 [1]
Telomerase Inhibitor IXIC50670.0 [1], 12100.0 [2], 12800.0 [3]
beta-RubromycinIC501320.0 [1], 1530.0 [2], 3000.0 [3], 3060.0 [4]
CID 11430774IC5045.0 [1], 52.0 [2], 63.0 [3], 5600.0 [4], 8400.0 [5]
Phen-DC3IC501.5 [1], 2.2 [2], 63.0 [3], 790.0 [4], 1500.0 [5]
StaurosporineIC504140.0 [1], 8300.0 [2], 8320.0 [3], 8970.0 [4]
(-)-Epigallocatechin gallateIC501000.0 [1], 1080.0 [2], 1180.0 [3]
Acridine orangeIC5012200.0 [1]
EthacridineIC508200.0 [1]
Acridine YellowIC5021700.0 [1]
(3R,4S,7R,10R)-3-[(1S,2S,4Ar,8aS)-2-methyl-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl]-10-hydroxy-5-oxa-1-azatricyclo[5.2.1.04,10]decane-2,6-dioneIC501300.0 [1]
Meso-tetrakis(N-methyl-4-pyridyl)porphine(4+)IC50550.0 [1], 710.0 [2], 740.0 [3]
N-[9,10-Dioxo-6-(3-pyrrolidin-1-ylpropanoylamino)anthracen-2-yl]-3-pyrrolidin-1-ylpropanamideIC501800.0 [1]
3-Pyrrolidin-1-YL-N-[6-(3-pyrrolidin-1-YL-propionylamino)-acridin-3-YL]-propionamideIC505200.0 [1]
3,6-Bis[3-(Azepan-1-Yl)propionamido]acridineIC503100.0 [1]
3,6-Bis[3-(heptamethyleneimino)piperizinopropionamido)acridineIC5050000.0 [1]
3,6-Bis(3-piperidinopropionamido)acridineIC502800.0 [1]
2,7-Bis[3-(piperidino)propionamido]anthraquinoneIC503100.0 [1], 8400.0 [2]
2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinonitrileIC507000.0 [1], 77000.0 [2], 113280.0 [3]
Tanshinone IIAIC50500.0 [1], 5000.0 [2]
TmpypIC5060.0 [1], 147.0 [2]
IsometamidiumIC50100.0 [1], 19054607.18 [2]
9,10-PhenanthrenequinoneIC50500.0 [1], 5000.0 [2]
7,8-DihydroxyflavoneIC5036000.0 [1]
HelenalinIC504000.0 [1]
CryptolepineIC509400.0 [1]
7,3',4'-TrihydroxyflavoneIC5040000.0 [1]
Syuiq-5IC50440.0 [1], 630.0 [2]
7,8,4'-TrihydroxyflavoneIC503000.0 [1]
2,6-Bis[3-(1-piperidinyl)propanoylamino]anthraquinoneIC504500.0 [1]
2,7-Bis[3-(Diethylamino)Propionamido]AnthraquinoneIC504300.0 [1]
ChrolactomycinIC50500.0 [1]
2,7-Bis[3-(Dimethylamino)Propionamido]AnthraquinoneIC504700.0 [1]
2,7-Bis[3-(pyrrolidino)propionamido]anthraquinoneIC502000.0 [1], 6700.0 [2]
N-[9-(4-Aminoanilino)-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamideIC5060.0 [1], 74.0 [2]
N-[9-[2-(1-Methylpyrrolidin-2-yl)ethylamino]-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamideIC5018.0 [1]
N',N'-Dimethyl-N-(16-nitro-4,12-diazapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-1(13),2(11),3,5,7,9,14(19),15,17,20-decaen-3-yl)propane-1,3-diamineIC50500.0 [1]
3-Morpholin-4-yl-N-[7-(3-morpholin-4-ylpropanoylamino)-9,10-dioxoanthracen-2-yl]propanamideIC5050000.0 [1]
3,6-Bis[(3-morpholinopropionamido)] acridineIC5050000.0 [1]
3,6-Bis[3-(4-methylpiperidino)propionamido]acridineIC501350.0 [1]
3-(1,3,3-Trimethyl-6-azabicyclo[3.2.1]octan-6-yl)-N-[6-[3-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)propanoylamino]acridin-3-yl]propanamideIC5050000.0 [1]
3-(4-Benzylpiperidin-1-yl)-N-[6-[3-(4-benzylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamideIC5050000.0 [1]
3-(2-Ethylpiperidin-1-yl)-N-[6-[3-(2-ethylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamideIC502700.0 [1]
3-Diethylamino-N-[6-(3-diethylamino-propionylamino)-acridin-3-yl]-propionamideIC505800.0 [1]
3-Dimethylamino-N-[6-(3-dimethylamino-propionylamino)-acridin-3-yl]-propionamideIC508200.0 [1]
3-(3-Methylpiperidin-1-yl)-N-[6-[3-(3-methylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamideIC504400.0 [1]
3-(2-Methylpiperidin-1-yl)-N-[6-[3-(2-methylpiperidin-1-yl)propanoylamino]acridin-3-yl]propanamideIC502600.0 [1]
3-[2-(Hydroxymethyl)piperidin-1-yl]-N-[6-[3-[2-(hydroxymethyl)piperidin-1-yl]propanoylamino]acridin-3-yl]propanamideIC505400.0 [1]
3-(4-Hydroxypiperidin-1-yl)-N-[6-[3-(4-hydroxypiperidin-1-yl)propanoylamino]acridin-3-yl]propanamideIC508000.0 [1]
3-[2-(2-Hydroxyethyl)piperidin-1-yl]-N-[6-[3-[2-(2-hydroxyethyl)piperidin-1-yl]propanoylamino]acridin-3-yl]propanamideIC504100.0 [1]
5-Morpholin-4-yl-2-[[(E)-3-naphthalen-2-ylbut-2-enoyl]amino]benzoic acidIC50470.0 [1]
4,11-Diaminonaphtho[2,3-f][1]benzothiole-5,10-dioneIC5010000.0 [1], 33000.0 [2]
9,12,15,29,32,35,42,44-Octazaheptacyclo[35.3.1.13,7.14,40.117,21.120,24.123,27]hexatetraconta-1(40),2,4(42),5,7(46),17(45),18,20(44),21,23,25,27(43),37(41),38-tetradecaeneIC50750.0 [1]
3-(4-Methylmorpholin-4-ium-4-yl)-N-[7-[3-(4-methylmorpholin-4-ium-4-yl)propanoylamino]-9,10-dioxoanthracen-2-yl]propanamideIC5016500.0 [1]
[3-[[9,10-Dioxo-7-[3-(trimethylazaniumyl)propanoylamino]anthracen-2-yl]amino]-3-oxopropyl]-trimethylazaniumIC5014500.0 [1]
3-(1-Methylpiperidin-1-ium-1-yl)-N-[7-[3-(1-methylpiperidin-1-ium-1-yl)propanoylamino]-9,10-dioxoanthracen-2-yl]propanamideIC507800.0 [1]
2-(3,4-Dimethoxyphenyl)-7,8-dihydroxy-4H-chromen-4-oneIC5011700.0 [1]
2-(3,4-Dihydroxyphenyl)-8-hydroxy-4H-chromen-4-oneIC5040000.0 [1]
4,11-Bis[2-(methylamino)ethylamino]naphtho[2,3-f][1]benzothiole-5,10-dione;hydrochlorideIC50500.0 [1], 700.0 [2]
2-[2-[[4-[2-(Diaminomethylideneamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl]amino]ethyl]guanidine;hydrochlorideIC5080.0 [1], 700.0 [2]
(3-Chlorophenyl) 12-[[2-[1-[3-(3-methylindol-1-yl)propyl]indol-3-yl]acetyl]amino]dodecyl hydrogen phosphate;N,N-diethylethanamineIC503400.0 [1], 79000.0 [2]
6-Formylpyridine-2-carbothionic acid-S-3,4-dichlorophenyl esterIC5024000.0 [1], 33090.0 [2]
1,4-Bis[[3-(4-methylmorpholinium-4-yl)propionyl]amino]-9,10-anthraquinoneIC5034500.0 [1]
[3-[[9,10-Dioxo-6-[3-(trimethylazaniumyl)propanoylamino]anthracen-2-yl]amino]-3-oxopropyl]-trimethylazaniumIC5017300.0 [1]
[3-[[7-[3-[Diethyl(methyl)azaniumyl]propanoylamino]-9,10-dioxoanthracen-2-yl]amino]-3-oxopropyl]-diethyl-methylazaniumIC5020000.0 [1]
2-[2-[(11-Amino-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl)amino]ethyl]guanidineIC50900.0 [1], 2000.0 [2]
2-[2-[(4-Amino-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl)amino]ethyl]guanidineIC50500.0 [1], 3000.0 [2]
2-[2-[[11-[2-(Methylamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidineIC50300.0 [1], 600.0 [2]
2-[2-[[4-[2-(Methylamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-11-yl]amino]ethyl]guanidineIC5050.0 [1], 1100.0 [2]
2-[2-[[11-(2-Aminoethylamino)-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidineIC50100.0 [1], 800.0 [2]
2-[2-[[11-(3-Aminopropylamino)-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]guanidineIC5070.0 [1], 700.0 [2]
N'-[2-[[11-[2-(1-Aminoethylideneamino)ethylamino]-5,10-dioxonaphtho[2,3-f][1]benzothiol-4-yl]amino]ethyl]ethanimidamideIC50300.0 [1], 470.0 [2]
1,4-Bis[[3-(1-methylpiperidinium-1-yl)propionyl]amino]-9,10-anthraquinoneIC5011100.0 [1]
12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl cyclohexyl hydrogen phosphateIC508700.0 [1], 101000.0 [2]
12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl (3-chlorophenyl) hydrogen phosphateIC502500.0 [1], 70000.0 [2]
12-[[2-[1-[2-(5-Chloroindol-1-yl)ethyl]indol-3-yl]acetyl]amino]dodecyl phenyl hydrogen phosphateIC506700.0 [1], 61000.0 [2]
DoxorubicinIC5073000.0 [1]
CamptothecinIC50300000.0 [1]
ResveratrolIC5085000.0 [1]
Oleic acidIC508600.0 [1]
BerberineIC5037000.0 [1]
1-(6-((3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dioneIC50200.0 [1]
CelastrolIC50780.0 [1]
AllicinIC50500.0 [1]
CostunolideIC5065000.0 [1]
2'-3'-Dideoxyguanosine-5'-triphosphateIC508600.0 [1]
Vaccenic acidIC5016000.0 [1]
Unii-ST04094S3XIC5037300.0 [1]
3',4'-DihydroxyflavoneIC5040000.0 [1]
Petroselinic acidIC5015000.0 [1]
3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-KL]acridin-13-iumIC50331131121.48 [1]
Altertoxin IIC501000000.0 [1]
7,8,3'-TrihydroxyflavoneIC5050000.0 [1]
MeridineIC5011000.0 [1]
OkaninIC506000.0 [1]
Telomerase Inhibitor IVIC50200.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Telomerase reverse transcriptase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/telomerase-reverse-transcriptase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Telomerase reverse transcriptase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/telomerase-reverse-transcriptase-inhibitors-ic50-ki.
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