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TRAF2- and NCK-interacting kinase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
5-(2,5-Dichlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamideIC50394.0 [1], 849.0 [2], 850.0 [3], 6177.0 [4]
DovitinibIC502.0 [1], 8.0 [2], 61.0 [3]
StaurosporineIC501.4 [1], 39.0 [2]
2-[3-[5-Chloro-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetonitrileIC505.4 [1], 65.0 [2]
4-Methoxy-3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyridin-4-yl]benzonitrileIC505.0 [1], 30000.0 [2]
4-(5-Chloro-2-methoxyphenyl)-N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]pyridin-2-amineIC504.0 [1], 7900.0 [2]
4-Methoxy-3-[2-(4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrileIC5011.0 [1], 26000.0 [2]
4-Methoxy-3-[2-[(3-Methoxy-4-Morpholin-4-Yl-Phenyl)amino]pyridin-4-Yl]benzenecarbonitrileIC508.0 [1], 6300.0 [2]
3-[2-[4-[4-(Dimethylamino)piperidin-1-yl]-3-fluoroanilino]pyridin-4-yl]-4-methoxybenzonitrileIC5011.0 [1], 3100.0 [2]
3-[2-[3-Methoxy-4-(4-methylpiperazin-1-yl)anilino]pyridin-4-yl]benzonitrileIC506.0 [1], 27000.0 [2]
DoramapimodIC5010000.0 [1]
N-{5-[(E)-2-Phenylethenyl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamideIC503570.0 [1]
5-(6-Aminopyridin-3-yl)-3-(4-chlorophenyl)pyridin-2-amineIC5015.0 [1]
5-(4-Methylbenzamido)-2-(phenylamino)thiazole-4-carboxamideKi100.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC505000.0 [1]
CID 71540619IC503.0 [1]
5-(3-Chloro-2-methylphenyl)-N-(4-sulfamoylphenyl)furan-2-carboxamideIC50260.0 [1]
4-[2-(3-Methoxy-4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrileIC501000.0 [1]
4-(5-Chloro-2-methoxyphenyl)-N-(3-methoxy-4-morpholin-4-ylphenyl)pyridin-2-amineIC5041.0 [1]
4-(5-Fluoro-2-methoxyphenyl)-N-(3-methoxy-4-morpholin-4-ylphenyl)pyridin-2-amineIC50118.0 [1]
N-(3-Methoxy-4-morpholin-4-ylphenyl)-4-[2-methoxy-5-(trifluoromethyl)phenyl]pyridin-2-amineIC50275.0 [1]
3-[2-(3-Methoxy-4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrileIC5055.0 [1]
3-Methoxy-5-[2-(3-methoxy-4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrileIC5063.0 [1]
4-(5-Chloro-2-methoxyphenyl)-N-[4-(2-morpholin-4-ylethyl)phenyl]pyridin-2-amineIC5020.0 [1]
2-[3-[2-[3-Methoxy-4-(4-methylpiperazin-1-yl)anilino]pyridin-4-yl]phenyl]acetonitrileIC50290.0 [1]
5-[[5-(Imidazol-1-ylmethyl)thiophene-3-carbonyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC508.7 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-[(6-methoxynaphthalen-2-yl)amino]-1,3-thiazole-4-carboxamideIC506.1 [1]
5-[[4-[(3-Hydroxyazetidin-1-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC505.6 [1]
5-[[4-[[(2R)-2-Hydroxypropyl]amino]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5016.8 [1]
5-[[4-[[(3S)-3-(Dimethylamino)pyrrolidin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC502.6 [1]
2-[(7-Fluoronaphthalen-2-yl)amino]-5-(3-methylbut-2-enoylamino)-1,3-thiazole-4-carboxamideIC507.2 [1]
2-(Naphthalen-2-ylamino)-5-[[4-[(4-nitroimidazol-1-yl)methyl]benzoyl]amino]-1,3-thiazole-4-carboxamideIC505.9 [1]
2-(Naphthalen-2-ylamino)-5-[[4-(1,2,4-triazol-1-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC502.5 [1]
5-[[4-[[2-(Hydroxymethyl)piperidin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC506.8 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-(quinolin-4-ylamino)-1,3-thiazole-4-carboxamideIC5026.5 [1]
2-(Naphthalen-2-ylamino)-5-[[4-(2-piperidin-1-ylethylamino)benzoyl]amino]-1,3-thiazole-4-carboxamideIC508.0 [1]
5-[[4-(4-Methylpiperazin-1-yl)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5010.2 [1]
5-[[5-(Imidazol-1-ylmethyl)thiophene-2-carbonyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC507.7 [1]
2-[(7-Fluoronaphthalen-2-yl)amino]-5-[[4-(2-hydroxyethylamino)benzoyl]amino]-1,3-thiazole-4-carboxamideIC5012.9 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-(quinolin-6-ylamino)-1,3-thiazole-4-carboxamideIC503.0 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-(quinolin-5-ylamino)-1,3-thiazole-4-carboxamideIC504.8 [1]
5-[[4-[2-(Dimethylamino)ethylamino]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC508.6 [1]
5-[[4-(4-Hydroxypiperidin-1-yl)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5012.7 [1]
5-[[4-[(2,4-Dioxo-1,3-thiazolidin-3-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5015.9 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-(quinolin-8-ylamino)-1,3-thiazole-4-carboxamideIC505.5 [1]
2-(Naphthalen-2-ylamino)-5-[[4-(pyrazol-1-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC5010.3 [1]
5-(But-2-ynoylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC504.4 [1]
2-(Naphthalen-2-ylamino)-5-[6-(1,2,4-triazol-1-yl)hex-2-ynoylamino]-1,3-thiazole-4-carboxamideIC5010.7 [1]
5-[[4-[[4-(Hydroxymethyl)imidazol-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.5 [1]
5-[[4-[[(3R)-3-Hydroxypyrrolidin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC505.5 [1]
5-[[4-(Imidazol-1-ylmethyl)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.0 [1]
2-(Naphthalen-2-ylamino)-5-[[4-(2H-tetrazol-5-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC502.9 [1]
5-[[3-Amino-4-(2-hydroxyethylamino)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5024.4 [1]
2-(Naphthalen-2-ylamino)-5-[[4-(tetrazol-1-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC505.9 [1]
5-[[4-[[4-(2-Hydroxyethyl)piperazin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC502.7 [1]
2-[[6-(Hydroxymethyl)naphthalen-2-yl]amino]-5-(3-methylbut-2-enoylamino)-1,3-thiazole-4-carboxamideIC501.6 [1]
5-[[4-[[(2S)-2-Hydroxypropyl]amino]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5015.1 [1]
5-[[4-(4-Methylpiperazin-1-yl)benzoyl]amino]-2-(quinolin-5-ylamino)-1,3-thiazole-4-carboxamideIC5015.6 [1]
5-(4-Hydroxybut-2-ynoylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC504.5 [1]
5-(Cyclopropanecarbonylamino)-2-[[6-(hydroxymethyl)naphthalen-2-yl]amino]-1,3-thiazole-4-carboxamideIC505.8 [1]
5-[[4-[[(3S)-3-Hydroxypyrrolidin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC505.0 [1]
5-[[5-[(4-Methylpiperazin-1-yl)methyl]thiophene-3-carbonyl]amino]-2-(quinolin-5-ylamino)-1,3-thiazole-4-carboxamideIC508.2 [1]
2-[(6-Fluoronaphthalen-2-yl)amino]-5-[[4-(2-hydroxyethylamino)benzoyl]amino]-1,3-thiazole-4-carboxamideIC5022.5 [1]
2-[Methyl(naphthalen-2-yl)amino]-5-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC5036.3 [1]
5-[[4-[(4-Hydroxypiperidin-1-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.4 [1]
2-[[6-(Hydroxymethyl)naphthalen-2-yl]amino]-5-[(5-methylthiophene-2-carbonyl)amino]-1,3-thiazole-4-carboxamideIC5011.1 [1]
5-[[(E)-4-(4-Methylpiperazin-1-yl)but-2-enoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5016.0 [1]
5-(5-Hydroxypent-2-ynoylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC504.0 [1]
5-[[4-[(5-Methyl-1,3,4-oxadiazol-2-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC506.2 [1]
2-(Naphthalen-2-ylamino)-5-[[4-[(3-nitro-1,2,4-triazol-1-yl)methyl]benzoyl]amino]-1,3-thiazole-4-carboxamideIC5014.8 [1]
5-(Cyclopropanecarbonylamino)-2-[(7-fluoronaphthalen-2-yl)amino]-1,3-thiazole-4-carboxamideIC5012.8 [1]
2-[(6-Methoxynaphthalen-2-yl)amino]-5-(3-methylbut-2-enoylamino)-1,3-thiazole-4-carboxamideIC5015.2 [1]
5-[(4-Aminobenzoyl)amino]-2-[(6-methoxynaphthalen-2-yl)amino]-1,3-thiazole-4-carboxamideIC509.7 [1]
2-(Naphthalen-2-ylamino)-5-[[4-[(3-oxopiperazin-1-yl)methyl]benzoyl]amino]-1,3-thiazole-4-carboxamideIC504.2 [1]
5-(3-Methylbut-2-enoylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5012.7 [1]
5-[[4-(2-Hydroxyethyl)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC505.8 [1]
5-(Cyclopropanecarbonylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5015.0 [1]
5-[[4-(2-Hydroxyethylamino)benzoyl]amino]-2-[(6-methoxynaphthalen-2-yl)amino]-1,3-thiazole-4-carboxamideIC5014.8 [1]
5-[[4-(Morpholin-4-ylmethyl)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC508.6 [1]
2-(Naphthalen-2-ylamino)-5-[[4-[(2-nitroimidazol-1-yl)methyl]benzoyl]amino]-1,3-thiazole-4-carboxamideIC509.5 [1]
5-[[4-[(2-Hydroxyethylamino)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.7 [1]
5-[[4-[[4-(Hydroxymethyl)triazol-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC505.3 [1]
2-[(7-Fluoronaphthalen-2-yl)amino]-5-[[4-(imidazol-1-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC508.4 [1]
5-[[4-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC5018.5 [1]
5-[[4-[4-(2-Hydroxyethyl)piperazin-1-yl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC507.2 [1]
2-[[6-(Hydroxymethyl)naphthalen-2-yl]amino]-5-(thiophene-3-carbonylamino)-1,3-thiazole-4-carboxamideIC505.5 [1]
2-[(6-Fluoronaphthalen-2-yl)amino]-5-[[4-(imidazol-1-ylmethyl)benzoyl]amino]-1,3-thiazole-4-carboxamideIC5010.1 [1]
2-[(4-Methoxynaphthalen-2-yl)amino]-5-(thiophene-3-carbonylamino)-1,3-thiazole-4-carboxamideIC5051.3 [1]
2-(Isoquinolin-6-ylamino)-5-(thiophene-3-carbonylamino)-1,3-thiazole-4-carboxamideIC5012.0 [1]
2-[(7-Fluoronaphthalen-2-yl)amino]-5-(6-morpholin-4-ylhexanoylamino)-1,3-thiazole-4-carboxamideIC5019.5 [1]
5-[[4-(2-Aminoethylamino)benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC508.4 [1]
2-[Methyl(quinolin-6-yl)amino]-5-[[5-(morpholin-4-ylmethyl)thiophene-3-carbonyl]amino]-1,3-thiazole-4-carboxamideIC505.7 [1]
5-(6-Imidazol-1-ylhex-2-ynoylamino)-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC509.7 [1]
2-(Quinolin-5-ylamino)-5-(thiophene-3-carbonylamino)-1,3-thiazole-4-carboxamideIC509.4 [1]
2-(Naphthalen-2-ylamino)-5-(1H-pyrrole-2-carbonylamino)-1,3-thiazole-4-carboxamideIC507.5 [1]
N-[4-Carbamoyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]-4H-thieno[3,2-b]pyrrole-5-carboxamideIC5022.7 [1]
2-[(7-Fluoronaphthalen-2-yl)amino]-5-(thiophene-3-carbonylamino)-1,3-thiazole-4-carboxamideIC5016.9 [1]
5-[[4-[(4-Methyl-1,4-diazepan-1-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.2 [1]
5-[[4-[[(3S)-3-Aminopyrrolidin-1-yl]methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC503.0 [1]
5-[[4-[(5-Methyltetrazol-1-yl)methyl]benzoyl]amino]-2-(naphthalen-2-ylamino)-1,3-thiazole-4-carboxamideIC507.1 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ TRAF2- and NCK-interacting kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/traf2-and-nck-interacting-kinase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ TRAF2- and NCK-interacting kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/traf2-and-nck-interacting-kinase-inhibitors-ic50-ki.
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