Transcription intermediary factor 1-alpha Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic Acid	IC50	10000.0 [1], 15848.93 [2]
	CID 91827373	IC50	1600.0 [1], 10000.0 [2]
	N-[6-(4-Methoxyphenoxy)-1,3-Dimethyl-2-Oxo-2,3-Dihydro-1h-Benzimidazol-5-Yl]benzenesulfonamide	IC50	730.0 [1], 1500.0 [2]
	Sgc-cbp30	IC50	20000.0 [1]
	N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-4-methoxybenzenesulfonamide	IC50	9300.0 [1]
	N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-5,6,7,8-tetrahydro-2-naphthalenesulfonamide	IC50	6170.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)benzenesulfonamide	IC50	23000.0 [1]
	N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	IC50	100000.0 [1]
	3-Cyano-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)benzenesulfonamide	IC50	10000.0 [1]
	3,4-Dimethoxy-N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]benzenesulfonamide	IC50	430.0 [1]
	N-[3-(3-Methyl-4-Oxo-4,5,6,7-Tetrahydro-2h-Isoindol-1-Yl)-4-Phenoxyphenyl]methanesulfonamide	IC50	10000.0 [1]
	1-[2-(2,4-Difluorophenoxy)-5-methylsulfonylphenyl]-3-methyl-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-4-one	IC50	10000.0 [1]
	N-[6-[3-(6-Aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	10.0 [1]
	N-[6-[3-(4-Aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	7.9 [1]
	N-[6-[3-(3-Methoxypropoxy)phenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	130.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	220.0 [1]
	N-[1,3-Dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxobenzimidazol-5-yl]cyclopropanesulfonamide	IC50	110.0 [1]
	N-[6-[3-(6-Aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	13.0 [1]
	N-[6-(3-Butoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	160.0 [1]
	N-[6-[3-(4-Aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	8.3 [1]
	N-[1,3-Dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	100.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	270.0 [1]
	N-[6-[3-(3-Aminopropoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	13.0 [1]
	N-[6-[3-(5-Aminopentoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	11.0 [1]
	N-[6-[3-(6-Hydroxyhexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	60.0 [1]
	N-[6-(3-Ethoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	180.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	53.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	43.0 [1]
	Tert-butyl N-[6-[3-[1,3-dimethyl-6-[(1-methylimidazol-4-yl)sulfonylamino]-2-oxobenzimidazol-5-yl]oxy-5-propoxyphenoxy]hexyl]carbamate	IC50	160.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-2,2-dimethyl-3,4-dihydrochromene-6-sulfonamide	IC50	3690.0 [1]
	(2S)-N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxine-6-sulfonamide	IC50	10000.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-3,4-dihydro-2H-chromene-6-sulfonamide	IC50	4630.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-2-methylbenzenesulfonamide	IC50	2620.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-3-methoxybenzenesulfonamide	IC50	2380.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide	IC50	10000.0 [1]
	N-(1-Methyl-2-oxo-3H-indol-5-yl)-4-methylsulfanylbenzenesulfonamide	IC50	17000.0 [1]
	N-(1-Methyl-2-oxo-3,4-dihydroquinolin-6-yl)-4-methylsulfanylbenzenesulfonamide	IC50	4800.0 [1]
	N-[6-[3-[4-(Dimethylamino)butoxy]phenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	270.0 [1]
	4-Cyclohexyl-N-(1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)benzenesulfonamide	IC50	2800.0 [1]
	N-(7-Methoxy-1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)benzenesulfonamide	IC50	36000.0 [1]
	N-(1-Methyl-2-oxo-3,4-dihydroquinolin-7-yl)-4-methylsulfanylbenzenesulfonamide	IC50	14000.0 [1]
	1,3-Dimethyl-5-[3-(2-methylpropoxy)phenoxy]benzimidazol-2-one	IC50	2400.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(4-phenylmethoxyphenoxy)benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	IC50	2000.0 [1]
	3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-5-(furan-2-yl)benzoic acid	IC50	20000.0 [1]
	3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-4-fluoro-5-(1-methylpyrazol-4-yl)benzoic acid	IC50	20000.0 [1]
	3-[(1-Acetylindole-3-carbonyl)amino]-4-fluorobenzoic acid	IC50	20000.0 [1]
	3-[(1-Acetylindole-3-carbonyl)amino]benzoic acid	IC50	20000.0 [1]
	3-[(1-Acetylindole-3-carbonyl)amino]-5-(oxan-2-yloxymethyl)benzoic acid	IC50	20000.0 [1]
	3-[(1-Acetyl-5-methoxyindole-3-carbonyl)amino]-5-(1-methylpyrazol-4-yl)benzoic acid	IC50	20000.0 [1]
	3-[(1-Acetylindole-3-carbonyl)amino]-5-(furan-2-yl)benzoic acid	IC50	10440.0 [1]
	N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	IC50	100000.0 [1]
	2,4-Dimethoxy-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)benzenesulfonamide	IC50	2500.0 [1]
	4-Cyclohexyl-N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)benzenesulfonamide	IC50	1700.0 [1]
	N-(1-Methyl-2-oxo-3,4-dihydroquinolin-6-yl)-4-(2-methylpropoxy)benzenesulfonamide	IC50	3700.0 [1]
	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamide	IC50	100000.0 [1]
	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamide	IC50	100000.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-4-(2-methylpropoxy)benzenesulfonamide	IC50	4000.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-3-fluoro-4-methylbenzenesulfonamide	IC50	10000.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-4-propan-2-ylbenzenesulfonamide	IC50	3450.0 [1]
	N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-2,3-dihydro-1H-indene-5-sulfonamide	IC50	10000.0 [1]
	4-Chloro-N-(1,3-dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)benzenesulfonamide	IC50	1560.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-3,4-dimethoxybenzenesulfonamide	IC50	480.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-3,4-dimethylbenzenesulfonamide	IC50	4770.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-4-methoxybenzenesulfonamide	IC50	740.0 [1]
	N-[6-(4-Methoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-2-methylbenzenesulfonamide	IC50	1470.0 [1]
	N-[6-(4-Methoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-4-propoxybenzenesulfonamide	IC50	8400.0 [1]
	4-Chloro-N-(1,3-dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-2-methylbenzenesulfonamide	IC50	2450.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-5-fluoro-2-methylbenzenesulfonamide	IC50	3420.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxybenzimidazol-5-yl)-3-fluoro-4-methylbenzenesulfonamide	IC50	2700.0 [1]
	N-[6-(4-Methoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]-4-methylbenzenesulfonamide	IC50	2700.0 [1]
	4-Methoxy-N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxobenzimidazol-5-yl]benzenesulfonamide	IC50	770.0 [1]
	N-(1,3-Dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-benzimidazol-5-yl)-4-methylbenzenesulfonamide	IC50	1270.0 [1]
	N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-4-(methylsulfanyl)benzenesulfonamide	IC50	4900.0 [1]
	3-[2-(2,4-Difluorophenoxy)-5-methylsulfonylphenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one	IC50	10000.0 [1]
	N-[1,3-Dimethyl-2-oxo-6-(3-phenylmethoxyphenoxy)benzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	140.0 [1]
	N-[1,3-Dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	IC50	57.0 [1]
	N-[6-[3-[4-(Dimethylamino)butoxy]-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	IC50	7.6 [1]
	1-Methyl-5-(2-Methyl-1,3-Thiazol-4-Yl)-1,3-Dihydro-2h-Indol-2-One	IC50	8500.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 78 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Transcription intermediary factor 1-alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/transcription-intermediary-factor-1-alpha-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Transcription intermediary factor 1-alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/transcription-intermediary-factor-1-alpha-inhibitors-ic50-ki.
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