Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N'-(3,4-Dimethoxybenzylidene)-2-(phenylsulfanyl)acetohydrazide	IC50	660.0 [1]
	(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-1,5-naphthyridin-2-ylmethylideneamino]cyclopropane-1-carboxamide	IC50	50000.0 [1]
	(1R,2R)-N-[(E)-[3-Methoxy-4-(pyridin-3-ylmethoxy)phenyl]methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	1600.0 [1]
	(1R,2R)-2-(6-Methoxypyridin-3-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	5000.0 [1]
	(1R,2R)-2-(5-Chloropyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	5400.0 [1]
	(1R,2R)-2-(6-Methoxypyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	410.0 [1]
	(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide	IC50	37.0 [1]
	(1R,2R)-2-(4-Fluorophenyl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	510.0 [1]
	(1R,2R)-N-[(E)-(8-Methoxyquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	90.0 [1]
	(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-chloroquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	650.0 [1]
	(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	800.0 [1]
	(1S,2S)-N-[(E)-(8-Methylquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	240.0 [1]
	(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-N-methyl-2-phenylcyclopropane-1-carboxamide	IC50	5000.0 [1]
	(1R,2R)-N-[(E)-(8-Chloroquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	340.0 [1]
	(1R,2R)-2-(3-Chlorophenyl)-N-[(E)-(8-methoxyquinolin-6-yl)methylideneamino]cyclopropane-1-carboxamide	IC50	45.0 [1]
	(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-(6-methylpyridin-2-yl)cyclopropane-1-carboxamide	IC50	3200.0 [1]
	(1R,2R)-N-[(E)-(8-Fluoroquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	550.0 [1]
	(1R,2R)-2-Phenyl-N-[(E)-[8-(trifluoromethyl)quinolin-6-yl]methylideneamino]cyclopropane-1-carboxamide	IC50	10000.0 [1]
	(1R,2R)-N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-quinolin-2-ylcyclopropane-1-carboxamide	IC50	610.0 [1]
	2-(3-Chlorophenyl)sulfanyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamide	IC50	55.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamide	IC50	30.0 [1]
	1-[2-(4-Chlorophenyl)ethyl]-3-[(E)-(3,4-dimethoxyphenyl)methylideneamino]urea	IC50	51.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-(2-methylquinolin-6-yl)methylideneamino]propanamide	IC50	30000.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-quinolin-7-ylmethylideneamino]propanamide	IC50	30000.0 [1]
	2-(3-Chlorophenyl)sulfanyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]acetamide	IC50	40.0 [1]
	N-[(E)-3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylideneamino]-3-(3,4-dimethylindol-1-yl)propanamide	IC50	24.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(1,7-dimethylindol-3-yl)propanamide	IC50	9.0 [1]
	3-[4-Chloro-3-[(dimethylamino)methyl]indol-1-yl]-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamide	IC50	1500.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methoxy-3-methylindol-1-yl)propanamide	IC50	6.0 [1]
	2-(3-Chlorophenyl)sulfonyl-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamide	IC50	1700.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-[4-(hydroxymethyl)-3-methylindol-1-yl]propanamide	IC50	260.0 [1]
	3-(3-Chloro-4-methylindol-1-yl)-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]propanamide	IC50	1.3 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-indol-1-ylpropanamide	IC50	170.0 [1]
	2-(3-Chlorophenyl)sulfanyl-N-[(E)-(4,5-dimethoxypyridin-2-yl)methylideneamino]propanamide	IC50	30000.0 [1]
	N-[(E)-(2-Methoxy-4-methylquinolin-6-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	2000.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methylindol-1-yl)propanamide	IC50	12.0 [1]
	N-[(E)-3,4-Dihydro-2H-1,5-benzodioxepin-7-ylmethylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	180.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-quinolin-6-ylmethylideneamino]propanamide	IC50	340.0 [1]
	N-[(E)-(4-Methyl-2,3-dihydro-1,4-benzoxazin-7-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	750.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamide	IC50	5.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-[3-(hydroxymethyl)phenyl]sulfanylacetamide	IC50	30000.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-(4-methylquinolin-6-yl)methylideneamino]propanamide	IC50	370.0 [1]
	1-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(2-phenylethyl)urea	IC50	200.0 [1]
	N-[(E)-(4-Methoxyquinolin-6-yl)methylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	120.0 [1]
	N-[(E)-(3-Chloro-4,5-dimethoxyphenyl)methylideneamino]-3-(3,4-dimethylindol-1-yl)propanamide	IC50	38.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3-methylpyrrolo[2,3-b]pyridin-1-yl)propanamide	IC50	680.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-3-ylmethoxy)phenyl]methylideneamino]propanamide	IC50	53.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridazin-3-ylmethoxy)phenyl]methylideneamino]propanamide	IC50	180.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-4-ylmethoxy)phenyl]methylideneamino]propanamide	IC50	46.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-quinolin-3-ylpropanamide	IC50	810.0 [1]
	2-(3-Chlorophenyl)sulfanyl-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]acetamide	IC50	830.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamide	IC50	2200.0 [1]
	3-(6-Methoxypyridin-2-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamide	IC50	2000.0 [1]
	3-(1-Methylindol-3-yl)-N-[(E)-(8-methylquinolin-6-yl)methylideneamino]propanamide	IC50	160.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyrazin-2-ylmethoxy)phenyl]methylideneamino]propanamide	IC50	60.0 [1]
	N-[(E)-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]methylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	500.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(1-methylindol-3-yl)propanamide	IC50	51.0 [1]
	(1R,2R)-N-[(E)-(8-Methylquinolin-6-yl)methylideneamino]-2-phenylcyclopropane-1-carboxamide	IC50	420.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-(8-methoxyquinolin-6-yl)methylideneamino]propanamide	IC50	1.4 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-(3-methoxy-4-phenylmethoxyphenyl)methylideneamino]propanamide	IC50	80.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-1,5-naphthyridin-2-ylmethylideneamino]propanamide	IC50	1300.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-(3-methylquinolin-6-yl)methylideneamino]propanamide	IC50	210.0 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-[3-methoxy-4-(pyridin-2-ylmethoxy)phenyl]methylideneamino]propanamide	IC50	66.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3-methylindol-1-yl)propanamide	IC50	17.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(4-methylbenzimidazol-1-yl)propanamide	IC50	2400.0 [1]
	3-(3-Methylindol-1-yl)-N-[(E)-pyrido[3,2-c]pyridazin-6-ylmethylideneamino]propanamide	IC50	430.0 [1]
	N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(3,4-dimethylindol-1-yl)propanamide	IC50	1.8 [1]
	3-(3,4-Dimethylindol-1-yl)-N-[(E)-(2-fluoro-4,5-dimethoxyphenyl)methylideneamino]propanamide	IC50	3.0 [1]
	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	IC50	39810.72 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 69 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/transient-receptor-potential-cation-channel-subfamily-m-member-5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Transient receptor potential cation channel subfamily M member 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/transient-receptor-potential-cation-channel-subfamily-m-member-5-inhibitors-ic50-ki.
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