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Transitional endoplasmic reticulum ATPase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
CB-5083IC5011.0 [1], 490.0 [2], 680.0 [3], 1030.0 [4]
N-Benzyl-2-(2-methoxybenzimidazol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amineIC5076.0 [1], 4240.0 [2], 4840.0 [3], 9340.0 [4]
1-[4-(Benzylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl]-2-methylindole-4-carboxamideIC5040.0 [1], 1790.0 [2], 2000.0 [3], 2860.0 [4]
N-Benzyl-2-(2-methylindol-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amineIC50192.0 [1], 2000.0 [2], 9150.0 [3], 15320.0 [4]
1-[4-(Benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl]-2-methylindole-4-carboxamideIC506.0 [1], 250.0 [2], 500.0 [3], 580.0 [4]
2-(2-Amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amineIC50815.0 [1], 6140.0 [2], 6610.0 [3]
(6R,7R,10R)-10-[(1E,3E)-Hepta-1,3-dienyl]-6,7-dihydroxy-3-methylidene-2-oxaspiro[4.5]dec-8-ene-1,4-dioneIC5026300.0 [1], 31200.0 [2], 180000.0 [3]
2-(2-Aminobenzimidazol-1-yl)-N-benzyl-8-(2-methoxyethoxy)quinazolin-4-amineIC50907.0 [1], 2000.0 [2]
N-[4-[3-(5-Fluoro-1H-indol-2-yl)phenyl]cyclohexyl]-1-propan-2-ylpiperidin-4-amineIC50180.0 [1], 4260.0 [2]
1-[3-(1H-Indol-2-yl)phenyl]-N-[2-(2-methyl-1,2,4-triazol-3-yl)ethyl]piperidin-4-amineIC50990.0 [1], 2400.0 [2]
2-(Benzimidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amineIC502000.0 [1], 5000.0 [2]
N-Benzyl-2-(2-methoxyindol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amineIC5043.0 [1], 2000.0 [2]
N-Benzyl-2-(2-ethylindol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amineIC50445.0 [1], 5000.0 [2]
2-[2-(Aminomethyl)indol-1-yl]-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amineIC50153.0 [1], 2000.0 [2]
N-Benzyl-2-(2-methylindol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amineIC5047.0 [1], 2000.0 [2]
N-Benzyl-2-(2-methoxybenzimidazol-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amineIC502000.0 [1], 3134.0 [2]
N-Benzyl-2-(2-methoxybenzimidazol-1-yl)-8-(2-methoxyethoxy)quinazolin-4-amineIC50370.0 [1], 2000.0 [2]
N-Benzyl-8-methoxy-2-(2-methylbenzimidazol-1-yl)quinazolin-4-amineIC50152.0 [1], 2000.0 [2]
N-Benzyl-8-methoxy-2-(2-methoxybenzimidazol-1-yl)quinazolin-4-amineIC50145.0 [1], 2000.0 [2]
N-Benzyl-8-methoxy-2-[2-(methylamino)benzimidazol-1-yl]quinazolin-4-amineIC50233.0 [1], 2000.0 [2]
[1-[4-(Benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl]indol-2-yl]methanolIC5068.0 [1], 2000.0 [2]
N-[1-[4-(Benzylamino)-8-methoxyquinazolin-2-yl]benzimidazol-2-yl]acetamideIC505000.0 [1]
N-Benzyl-2-[2-(methoxymethyl)indol-1-yl]-5,6,7,8-tetrahydroquinazolin-4-amineIC50795.0 [1], 2000.0 [2]
N-Benzyl-2-[2-(dimethylamino)benzimidazol-1-yl]-8-methoxyquinazolin-4-amineIC50227.0 [1], 2000.0 [2]
N-Benzyl-5-(2-methoxybenzimidazol-1-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amineIC50180.0 [1], 2000.0 [2]
3-[4-(Benzylamino)-8-methoxyquinazolin-2-yl]-1H-benzimidazol-2-oneIC501068.0 [1], 2000.0 [2]
N-Benzyl-2-(2-ethylbenzimidazol-1-yl)-8-methoxyquinazolin-4-amineIC502000.0 [1], 5000.0 [2]
4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenolIC5070.0 [1]
CID 71521142IC5024.0 [1]
4-(4-Pyridin-3-yl-thiazol-2-ylamino)-phenolIC50300.0 [1]
Elisabatin AIC50100000.0 [1]
2-Chloro-N-[3-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]phenyl]acetamideIC50370.0 [1]
5-Phenoxymethyl-4-phenyl-4H-[1,2,4]triazole-3-thiolIC5030000.0 [1]
4-(4-(Thiophen-2-yl)thiazol-2-ylamino)phenolIC50110.0 [1]
4-{[(4-Methyl-6-phenyl-2-pyrimidinyl)thio]methyl}benzoic acidIC504800.0 [1]
4-(4-(Naphthalen-2-yl)thiazol-2-ylamino)phenolIC501300.0 [1]
4-(4-Phenyl-thiazol-2-ylamino)-phenolIC50190.0 [1]
4-{[4-(4-Pyridinyl)-1,3-thiazol-2-yl]amino}phenolIC50290.0 [1]
4-Bromo-2-[(1R,2S)-1,2-dimethyl-3-methylidenecyclopentyl]-5-methylphenolIC50100000.0 [1]
4-{[4-(2-Pyridinyl)-1,3-thiazol-2-yl]amino}phenolIC50230.0 [1]
3-(3-Cyclopentylsulfanyl-5-phenoxymethyl-[1,2,4]triazol-4-yl)-pyridineIC50470.0 [1]
4-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]amino}phenolIC502000.0 [1]
3-Isopropylsulfanyl-5-phenoxymethyl-4-phenyl-4H-[1,2,4]triazoleIC502690.0 [1]
4-(4-(3,4-Dichlorophenyl)thiazol-2-ylamino)phenolIC50430.0 [1]
4-[[[4-(1-Benzofuran-2-yl)-6-(benzylamino)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxamideIC5061.0 [1]
4-[[[4-(Benzylamino)-6-(1H-indazol-5-yl)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxamideIC5071.0 [1]
4-[[[4-(1-Benzothiophen-3-yl)-6-(benzylamino)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxamideIC5074.0 [1]
1-(3-(5-Fluoro-1h-Indol-2-Yl)phenyl)piperidin-4-Yl)(2-(4-Isopropyl-Piperazin1-Yl)ethyl)-CarbamateIC5070.0 [1]
3-Benzylsulfanyl-5-(phenoxymethyl)-4-phenyl-1,2,4-triazoleIC5030000.0 [1]
1-[4-(Benzylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl]-2-methyl-N-propan-2-ylindole-4-carboxamideIC504832.0 [1]
4-[(4-Methyl-6-phenylpyrimidin-2-yl)sulfanylmethyl]-N-(trifluoromethylsulfonyl)benzamideIC5021600.0 [1]
4-[2-(4-Methyl-6-phenylpyrimidin-2-yl)sulfanylethyl]benzoic acidIC5020500.0 [1]
4-(4-Methyl-6-phenylpyrimidin-2-yl)sulfanylbenzoic acidIC5037000.0 [1]
4-[(4-Methyl-6-phenylpyrimidin-2-yl)sulfonylmethyl]benzoic acidIC5037000.0 [1]
4-[[(4-Methyl-6-phenylpyrimidin-2-yl)amino]methyl]benzoic acidIC5015400.0 [1]
3-[[(4-Methyl-6-phenylpyrimidin-2-yl)amino]methyl]benzoic acidIC5037000.0 [1]
4-[[(4-Methyl-6-phenylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC502600.0 [1]
4-[[(4-Phenylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC508700.0 [1]
4-[[[4-Methyl-6-(2-methylphenyl)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5037000.0 [1]
4-[[[4-(2-Methoxyphenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5037000.0 [1]
4-[[[4-Methyl-6-(3-methylphenyl)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5011400.0 [1]
4-[[[4-(3-Chlorophenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC504800.0 [1]
4-[[[4-(3-Methoxyphenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5037000.0 [1]
4-[[[4-Methyl-6-(4-methylphenyl)pyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC502700.0 [1]
4-[[[4-(4-Chlorophenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC502600.0 [1]
4-[[[4-(4-Fluorophenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC508400.0 [1]
4-[[[4-(4-Methoxyphenyl)-6-methylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5037000.0 [1]
4-[[(4,6-Diphenylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC50300.0 [1]
4-[[[4-(2-Methylphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50673.0 [1]
4-[[[4-(2-Fluorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50141.0 [1]
4-[[[4-(2-Chlorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50700.0 [1]
4-[[[4-(2-Methoxyphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC503041.0 [1]
4-[[[4-(3-Methylphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50578.0 [1]
4-[[[4-(3-Fluorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50552.0 [1]
4-[[[4-(3-Chlorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50483.0 [1]
4-[[[4-(3-Methoxyphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50543.0 [1]
4-[[[4-(3-Methylsulfonylphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50116.0 [1]
4-[[[4-(3-Nitrophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50201.0 [1]
4-[[[4-(3-Azidophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50879.0 [1]
4-[[[4-(4-Methylphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50577.0 [1]
4-[[[4-(4-Fluorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50742.0 [1]
4-[[[4-(4-Chlorophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50221.0 [1]
4-[[[4-(4-Methoxyphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50921.0 [1]
4-[[[4-(4-Methylsulfonylphenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC501091.0 [1]
4-[[[4-(4-Nitrophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC502189.0 [1]
4-[[[4-(4-Aminophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50112.0 [1]
4-[[[4-(4-Amino-3-nitrophenyl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5060.0 [1]
4-[[[4-(1H-Indol-5-yl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50150.0 [1]
4-[[[4-(Furan-2-yl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC50570.0 [1]
4-[[(4-Phenyl-6-pyridin-3-ylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC501201.0 [1]
4-[[(4-Phenyl-6-pyridin-4-ylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC501667.0 [1]
4-[[[4-(Furan-3-yl)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC502188.0 [1]
4-[[[4-(Benzylamino)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC5027.0 [1]
4-[[(4-Anilino-6-phenylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC5036.0 [1]
4-[[[4-(Cyclohexylamino)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxylic acidIC504313.0 [1]
4-[[(4-Morpholin-4-yl-6-phenylpyrimidin-2-yl)amino]methyl]cyclohexane-1-carboxylic acidIC5010000.0 [1]
4-[[[4-(Benzylamino)-6-phenylpyrimidin-2-yl]amino]methyl]cyclohexane-1-carboxamideIC50127.0 [1]
4-[[[4-(Benzylamino)-6-phenylpyrimidin-2-yl]amino]methyl]-N-methylcyclohexane-1-carboxamideIC50448.0 [1]
4-[[[4-(Benzylamino)-6-phenylpyrimidin-2-yl]amino]methyl]-N-methylsulfonylcyclohexane-1-carboxamideIC50133.0 [1]
4-[[[4-(Benzylamino)-6-phenylpyrimidin-2-yl]amino]methyl]-N-(trifluoromethylsulfonyl)cyclohexane-1-carboxamideIC50264.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Transitional endoplasmic reticulum ATPase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/transitional-endoplasmic-reticulum-atpase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Transitional endoplasmic reticulum ATPase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/transitional-endoplasmic-reticulum-atpase-inhibitors-ic50-ki.
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