 | Bis(5-amidino-2-benzimidazolyl)methane | IC50 | 51.0 [1] |
| Bis(5-amidino-2-benzimidazolyl)methane | Ki | 140.0 [1] |
 | Ethyl N-[(2S)-6-amino-1-oxo-1-[5-[[4-(2-phenylethoxy)phenyl]methyl]-1,2,4-oxadiazol-3-yl]hexan-2-yl]carbamate | Ki | 5.4 [1], 46.5 [2] |
 | [4-[3-(Aminomethyl)phenyl]piperidin-1-yl]-(1-butyl-7-methylindol-3-yl)methanone | IC50 | 68.0 [1], 3694.0 [2] |
| [4-[3-(Aminomethyl)phenyl]piperidin-1-yl]-(1-butyl-7-methylindol-3-yl)methanone | Ki | 68.0 [1] |
 | Benzyl N-[(2S)-6-amino-1-oxo-1-[5-[[4-(2-phenylethoxy)phenyl]methyl]-1,2,4-oxadiazol-3-yl]hexan-2-yl]carbamate | Ki | 12.0 [1] |
 | (2R)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide | IC50 | 2.0 [1] |
| (2R)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide | Ki | 14000.0 [1] |
 | N-[(2S)-6-Amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,4-difluorobenzamide;hydrochloride | Ki | 7.6 [1], 400.0 [2] |
 | N-[(2S)-6-Amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-4-fluorobenzamide | Ki | 2.5 [1], 400.0 [2] |
 | Grassystatin A | IC50 | 10000.0 [1] |
 | [5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-[[4-(diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carboxylate | Ki | 0.07 [1] |
 | 4-[2-[4-(Diaminomethylideneamino)phenyl]-4-oxo-4-(2-phenylethylamino)butanoyl]-N-(3,3-diphenylpropyl)piperazine-1-carboxamide | Ki | 210.0 [1] |
 | 1,4-Bis[[4-(4-amidinobenzoylaminomethyl)piperidino]carbonyloxymethyl]benzene | Ki | 0.4 [1] |
 | [5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-(benzylcarbamoyl)piperazine-1-carboxylate | Ki | 15000.0 [1] |
 | [5-[4-(Benzylcarbamoyl)piperazine-1-carbonyl]oxycyclooctyl] 4-(benzylcarbamoyl)piperazine-1-carboxylate | Ki | 101000.0 [1] |
 | N-[(2S)-6-Amino-1-[5-[[4-[2-(3-chlorophenyl)ethylcarbamoyl]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,5-difluorobenzamide | Ki | 1.5 [1] |
 | Ethyl N-[(2S)-6-amino-1-[5-[[4-(2,3-dihydro-1H-inden-2-ylcarbamoyl)phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]carbamate | Ki | 2.8 [1] |
 | 1,4-Bis[[2-oxo-2-[4-(aminomethyl)benzylamino]ethyl]carbamoyloxymethyl]benzene | Ki | 0.6 [1] |
 | 4-[[(4-Carbamimidoylbenzoyl)amino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 84.0 [1] |
 | N-[2-[3-[4-(Aminomethyl)phenyl]propylamino]ethyl]-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | IC50 | 190.0 [1] |
 | N-(2-((3-(4-(Aminomethyl)phenyl)propyl)(methyl)amino)ethyl)naphthalene-2-sulfonamide | IC50 | 120.0 [1] |
 | N-[2-[3-[4-(Aminomethyl)phenyl]propylamino]ethyl]-2,3-dihydro-1H-indene-5-sulfonamide | IC50 | 200.0 [1] |
 | N-(2-(3-(4-(Aminomethyl)phenyl)propylamino)ethyl)naphthalene-2-sulfonamide | IC50 | 73.0 [1] |
 | N-(2-(3-(4-(Aminomethyl)phenyl)propylamino)ethyl)benzo[b]thiophene-5-sulfonamide | IC50 | 210.0 [1] |
 | N-(2-(3-(4-(Aminomethyl)phenyl)propylamino)ethyl)-1-chloronaphthalene-2-sulfonamide | IC50 | 5.0 [1] |
 | Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[4-[(2S,5S)-5-[4-[4-(diaminomethylideneamino)butanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butylamino]-1-oxopentan-2-yl]carbamate | IC50 | 2200.0 [1] |
 | N-[(2S)-5-(Diaminomethylideneamino)-1-[4-[(2S,5S)-5-[4-[4-(diaminomethylideneamino)butanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butylamino]-1-oxopentan-2-yl]benzamide | IC50 | 2400.0 [1] |
 | 3-[4-[5-(Aminomethyl)-2-fluorophenyl]piperidine-1-carbonyl]-5-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)benzamide | Ki | 1.3 [1] |
 | 2-[5-[[5-(Aminomethyl)-2,4-dimethylphenyl]methylamino]-3-chloro-2-methyl-6-oxopyrazin-1-yl]-N-[3-(aminomethyl)phenyl]acetamide;2,2,2-trifluoroacetic acid | Ki | 93.0 [1] |
 | (2S,4R)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide;nitric acid | Ki | 10.0 [1] |
 | 4-[[(4-Carbamimidoylbenzoyl)amino]methyl]-N-(3,3-diphenylpropyl)benzamide | Ki | 340.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(3,3,3-triphenylpropyl)piperazine-1,4-dicarboxamide | Ki | 6900.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(3,3-diphenylpropyl)piperazine-1,4-dicarboxamide | Ki | 870.0 [1] |
 | 4-[2-(4-Carbamimidoylanilino)-2-oxoethyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 300.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(2-naphthalen-1-ylethyl)piperazine-1,4-dicarboxamide | Ki | 7400.0 [1] |
 | 4-[2-[(4-Carbamimidoylbenzoyl)amino]ethyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 11000.0 [1] |
 | 4-[[(3-Carbamimidoylbenzoyl)amino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 24000.0 [1] |
 | 4-[[[4-(Diaminomethylideneamino)benzoyl]amino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 9800.0 [1] |
 | 4-[[(4-Carbamimidoylphenyl)sulfonylamino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 9700.0 [1] |
 | 4-N-Benzyl-1-N-[[4-(diaminomethylideneamino)phenyl]methyl]-4-N-methylpiperazine-1,4-dicarboxamide | Ki | 80000.0 [1] |
 | 4-N-Benzyl-1-N-[[4-(diaminomethylideneamino)phenyl]methyl]-4-N-(3-phenylpropyl)piperazine-1,4-dicarboxamide | Ki | 12000.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(4-phenylbutyl)piperazine-1,4-dicarboxamide | Ki | 11000.0 [1] |
 | 4-N,4-N-Dibenzyl-1-N-[[4-(diaminomethylideneamino)phenyl]methyl]piperazine-1,4-dicarboxamide | Ki | 29000.0 [1] |
 | 4-[[(4-Carbamimidoylbenzoyl)-methylamino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 50000.0 [1] |
 | 2-(4-Guanidinophenyl)-3-oxo-3-[4-(3,3-diphenylpropylcarbamoyl)piperazino]propionic acid methyl ester | Ki | 160.0 [1] |
 | 4-N-[(4-Carbamimidoylphenyl)methyl]-1-N-(3,3-diphenylpropyl)piperazine-1,4-dicarboxamide | Ki | 400.0 [1] |
 | 4-[2-[4-(Diaminomethylideneamino)phenyl]acetyl]-N-(3,3-diphenylpropyl)piperazine-1-carboxamide | Ki | 7000.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-[2-(9H-fluoren-9-yl)ethyl]piperazine-1,4-dicarboxamide | Ki | 6900.0 [1] |
 | 1-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-4-N-(4,4-diphenylcyclohexyl)piperazine-1,4-dicarboxamide | Ki | 890.0 [1] |
 | 1-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-4-N-(naphthalen-2-ylmethyl)piperazine-1,4-dicarboxamide | Ki | 1300.0 [1] |
 | 3-[[(4-Carbamimidoylbenzoyl)amino]methyl]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 13000.0 [1] |
 | 1-N-Benzyl-4-N-[[4-(diaminomethylideneamino)phenyl]methyl]piperazine-1,4-dicarboxamide | Ki | 16000.0 [1] |
 | 4-[(4-Carbamimidoylbenzoyl)amino]-N-(3,3-diphenylpropyl)piperidine-1-carboxamide | Ki | 2600.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-ethylpiperazine-1,4-dicarboxamide | Ki | 370000.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(3-phenylpropyl)piperazine-1,4-dicarboxamide | Ki | 7300.0 [1] |
 | 4-N-[[4-(Diaminomethylideneamino)phenyl]methyl]-1-N-(2-phenylethyl)piperazine-1,4-dicarboxamide | Ki | 42000.0 [1] |
 | 1,4-Bis[1,4-dioxo-4-[4-(aminomethyl)benzylamino]butylaminomethyl]benzene | Ki | 3.0 [1] |
 | 1,4-Bis[methyl[1,4-dioxo-4-[4-(aminomethyl)benzylamino]butyl]aminomethyl]benzene | Ki | 5.0 [1] |
 | 1,4-Bis[1,4-dioxo-4-[methyl[4-(aminomethyl)benzyl]amino]butylaminomethyl]benzene | Ki | 2000.0 [1] |
 | 1,4-Bis[1,3-dioxo-3-(4-guanidinobenzylamino)propylaminomethyl]benzene | Ki | 680.0 [1] |
 | 1,4-Bis[1,3-dioxo-3-[4-(aminomethyl)benzylamino]propylaminomethyl]benzene | Ki | 150.0 [1] |
 | 1,4-Bis[1,5-dioxo-5-(4-guanidinobenzylamino)pentylaminomethyl]benzene | Ki | 100.0 [1] |
 | [5-[2-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoylamino]acetyl]oxycyclooctyl] 2-[[4-(diaminomethylideneamino)phenyl]methylcarbamoylamino]acetate | Ki | 2.0 [1] |
 | 1,4-Bis[[3-oxo-3-(4-guanidinobenzylamino)propyl]carbamoyloxymethyl]benzene | Ki | 90.0 [1] |
 | 1,4-Bis[[2-oxo-2-(4-guanidinobenzylamino)ethyl]carbamoyloxymethyl]benzene | Ki | 10.0 [1] |
 | 1,4-Bis[1,4-dioxo-4-(4-guanidinobenzylamino)butylaminomethyl]benzene | Ki | 40.0 [1] |
 | 1,4-Bis[1,5-dioxo-5-[4-(aminomethyl)benzylamino]pentylaminomethyl]benzene | Ki | 9.0 [1] |
 | 1,4-Bis[[(S)-1-methyl-2-oxo-2-[4-(aminomethyl)benzylamino]ethyl]carbamoyloxymethyl]benzene | Ki | 366.0 [1] |
 | 1,4-Bis[[(R)-1-methyl-2-oxo-2-[4-(aminomethyl)benzylamino]ethyl]carbamoyloxymethyl]benzene | Ki | 31.0 [1] |
 | 1,4-Bis[methyl[2-oxo-2-[4-(aminomethyl)benzylamino]ethyl]carbamoyloxymethyl]benzene | Ki | 5.0 [1] |
 | 2-Acetamido-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]acetamide;2,2,2-trifluoroacetic acid | Ki | 470.0 [1] |
 | (2S)-2-Acetamido-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide;2,2,2-trifluoroacetic acid | Ki | 41.0 [1] |
 | (2S)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]azetidine-2-carboxamide;2,2,2-trifluoroacetic acid | Ki | 20.0 [1] |
 | 1-[(2S)-5-(Diaminomethylideneamino)-2-[(1-hydroxynaphthalene-2-carbonyl)amino]pentanoyl]pyrrolidine-2-carboxamide | Ki | 330.0 [1] |
 | (2S)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2,5-dihydropyrrole-2-carboxamide;2,2,2-trifluoroacetic acid | Ki | 38.0 [1] |
 | N-[1-(1,3-Benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]cyclopentanecarboxamide;2,2,2-trifluoroacetic acid | Ki | 88.0 [1] |
 | (2S)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | Ki | 19.0 [1] |
 | (2S)-1-Acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-oxopyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | Ki | 73.0 [1] |
 | (2S)-N-[(2S)-1-(1,3-Benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | Ki | 6.5 [1] |
 | Methyl 3-[3-(aminomethyl)phenyl]-2-[4-[[2-[(2S,5R)-5-[2-[[4-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-4-oxobutyl]amino]-2-oxoethyl]-3,6-dioxopiperazin-2-yl]acetyl]amino]butanoylamino]propanoate | Ki | 350.0 [1] |
 | Methyl 3-[3-(aminomethyl)phenyl]-2-[3-[[2-[(2S,5R)-5-[2-[[3-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-3-oxopropyl]amino]-2-oxoethyl]-3,6-dioxopiperazin-2-yl]acetyl]amino]propanoylamino]propanoate | Ki | 10.0 [1] |
 | Methyl 3-[3-(aminomethyl)phenyl]-2-[3-[(2S,5R)-5-[2-[[2-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]-3,6-dioxopiperazin-2-yl]propanoylamino]propanoate | Ki | 180.0 [1] |
 | (R)-2-Acetylamino-3-(3-aminomethyl-phenyl)-propionic acid methyl ester | Ki | 13700.0 [1] |
 | Methyl 3-[3-(aminomethyl)phenyl]-2-[3-[(5R)-5-[3-[[3-[3-(aminomethyl)phenyl]-1-methoxy-1-oxopropan-2-yl]amino]-3-oxopropyl]-3,6-dioxopiperazin-2-yl]propanoylamino]propanoate | Ki | 2400.0 [1] |
 | (R)-2-Acetylamino-3-(4-aminomethyl-phenyl)-propionic acid methyl ester | Ki | 213000.0 [1] |
 | N-[4-[(2S,5S)-5-[4-[[2-(2-Amino-4,5-dihydroimidazol-1-yl)acetyl]amino]butyl]-3,6-dioxopiperazin-2-yl]butyl]-4-(diaminomethylideneamino)benzamide | IC50 | 4400.0 [1] |
 | N-(3-Carbamimidoylphenyl)-2-[(2S,5S)-5-[4-[[2-(diaminomethylideneamino)acetyl]amino]butyl]-3,6-dioxopiperazin-2-yl]acetamide | IC50 | 19900.0 [1] |
 | N-[4-[(2S,5S)-5-[2-(3-Carbamimidoylanilino)-2-oxoethyl]-3,6-dioxopiperazin-2-yl]butyl]-3-(diaminomethylideneamino)propanamide | IC50 | 23600.0 [1] |
 | N-[4-[(2S,5S)-5-[2-(3-Carbamimidoylanilino)-2-oxoethyl]-3,6-dioxopiperazin-2-yl]butyl]-3-[carbamimidoyl(methyl)amino]propanamide | IC50 | 12800.0 [1] |
 | N-[4-[(2S,5S)-5-[2-(3-Carbamimidoylanilino)-2-oxoethyl]-3,6-dioxopiperazin-2-yl]butyl]-4-(diaminomethylideneamino)butanamide | IC50 | 21300.0 [1] |
 | 9H-Fluoren-9-ylmethyl N-[1-[4-[(2S,5S)-5-[2-(3-carbamimidoylanilino)-2-oxoethyl]-3,6-dioxopiperazin-2-yl]butylamino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate | IC50 | 9090.0 [1] |
 | N-[(2S)-1-[4-[(2S,5S)-5-[2-(3-Carbamimidoylanilino)-2-oxoethyl]-3,6-dioxopiperazin-2-yl]butylamino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]benzamide | IC50 | 12400.0 [1] |
 | 4-(Diaminomethylideneamino)-N-[4-[(2S,5S)-5-[4-[4-(diaminomethylideneamino)butanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butyl]butanamide | IC50 | 4700.0 [1] |
 | N-[(2S)-5-(Diaminomethylideneamino)-1-[4-[(2S,5S)-5-[4-[5-(diaminomethylideneamino)pentanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butylamino]-1-oxopentan-2-yl]benzamide | IC50 | 9300.0 [1] |
 | Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[4-[(2S,5S)-5-[4-[5-(diaminomethylideneamino)pentanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butylamino]-1-oxopentan-2-yl]carbamate | IC50 | 5700.0 [1] |
 | Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[4-[(2S,5S)-5-[4-[[(2S)-5-(diaminomethylideneamino)-2-(phenylmethoxycarbonylamino)pentanoyl]amino]butyl]-3,6-dioxopiperazin-2-yl]butylamino]-1-oxopentan-2-yl]carbamate | IC50 | 4100.0 [1] |
 | N-[4-[(2S,5S)-5-[4-[3-[Carbamimidoyl(methyl)amino]propanoylamino]butyl]-3,6-dioxopiperazin-2-yl]butyl]-3-(diaminomethylideneamino)propanamide | IC50 | 5900.0 [1] |
 | N-[3-(Aminomethyl)phenyl]-2-[3-chloro-2-methyl-6-oxo-5-(piperidin-3-ylmethylamino)pyrazin-1-yl]acetamide | Ki | 518.0 [1] |
 | 3-[4-[3-(Aminomethyl)phenyl]piperidine-1-carbonyl]-5-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)benzamide | Ki | 1.5 [1] |
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