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Tryptophan 2,3-dioxygenase Inhibitors (IC50, Ki)
Structure
Compound Name
Standard Type
Standard Values (in nM)
6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indoleIC50280.0 [1], 376.5 [2], 1300.0 [3]
6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indoleKi30.0 [1], 880.0 [2]
4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamideIC503000.0 [1], 10000.0 [2], 70000.0 [3]
(E)-3-(2-(1H-Tetrazol-5-YL)vinyl)-6-fluoro-1H-indoleIC50620.0 [1], 28000.0 [2]
(E)-3-(2-(1H-Tetrazol-5-YL)vinyl)-6-fluoro-1H-indoleKi5600.0 [1]

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References
This online resource may be cited as follows
MLA
"Quest Database™ Tryptophan 2,3-dioxygenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 4 Nov. 2025, https://www.aatbio.com/data-sets/tryptophan-2-3-dioxygenase-inhibitors-ic50-ki.
APA
AAT Bioquest, Inc. (2025, November 4). Quest Database™ Tryptophan 2,3-dioxygenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/tryptophan-2-3-dioxygenase-inhibitors-ic50-ki.
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