Structure | Compound Name | Standard Type | Standard Values (in nM) |
|---|---|---|---|
| Nutlin-3A | IC50 | 70.0 [1] | |
| Nutlin-3A | Ki | 55.0 [1], 230.0 [2] | |
| 2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid | IC50 | 1.0 [1], 1.1 [2], 4.2 [3], 6.0 [4] | |
| 2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-pentan-3-ylpiperidin-3-yl]acetic acid | IC50 | 2.8 [1], 3.0 [2], 36.3 [3], 55.0 [4] | |
| 2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-propan-2-ylpiperidin-3-yl]acetic acid | IC50 | 6.0 [1], 9.0 [2], 30.0 [3], 119.0 [4] | |
MLA | "Quest Database™ Tumour suppressor p53/oncoprotein Mdm2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 5 Dec. 2025, https://www.aatbio.com/data-sets/tumour-suppressor-p53-oncoprotein-mdm2-inhibitors-ic50-ki. | |
APA | AAT Bioquest, Inc. (2025, December 5). Quest Database™ Tumour suppressor p53/oncoprotein Mdm2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/tumour-suppressor-p53-oncoprotein-mdm2-inhibitors-ic50-ki. | |
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