X
Navigation Menu
Products
Services
Tools
Resources
logo
AAT Bioquest

 
search
logo
AAT Bioquest
Contact us
Company
Telephone:1-408-733-1055
Fax:1-408-733-1304
Hours:Monday to Friday
8:30 - 17:30 PST (GMT-8)
Location:5775 W Las Positas Blvd.
Pleasanton, CA, 94588
USA

Email us
Sales:sales@aatbio.com
Technical Support:support@aatbio.com
Website:websupport@aatbio.com
General Inquiries:info@aatbio.com
Order info
United States of America
Telephone:1-408-733-1055
Fax:1-408-733-1304
Email:sales@aatbio.com
Purchase Order:sales@aatbio.com

International
Click here to see all available distributors
Products
Services
Tools
Resources
 
search
calculatorCalculator

Type-1 angiotensin II receptor Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
LosartanIC500.33 [1], 8.0 [2], 28.0 [3], 88.0 [4]
LosartanKi12.0 [1], 17.0 [2]
TelmisartanIC503.0 [1], 150.0 [2]
SaralasinIC500.57 [1], 1.0 [2]
SaralasinKi0.22 [1], 0.33 [2]
IrbesartanIC500.9 [1], 20.8 [2]
IrbesartanKi0.8 [1], 1.1 [2], 2.0 [3]
Angiotensin IIIC500.72 [1]
Angiotensin IIKi0.16 [1], 0.5 [2], 0.9 [3]
CandesartanIC500.69 [1], 10.72 [2], 110.0 [3]
CandesartanKi10.4 [1]
Butyl 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamateKi10000.0 [1]
Bms-248360IC506.0 [1]
Bms-248360Ki10.0 [1]
ValsartanIC502.7 [1]
ValsartanKi3.0 [1], 4700.0 [2]
2-Ethyl-7-methyl-5-(2-methylpropyl)-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]imidazo[4,5-b]pyridineIC501.6 [1]
2-Ethyl-7-methyl-5-(2-methylpropyl)-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]imidazo[4,5-b]pyridineKi0.69 [1]
Angiotensin IVKi407.38 [1]
EprosartanIC502.0 [1], 7.3 [2]
TasosartanIC5032.0 [1], 38.0 [2]
2-Ethyl-5,7-dimethyl-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)imidazo(4,5-b)pyridineIC500.3 [1], 2.7 [2]
(1,1'-Biphenyl)-2-sulfonamide, N-(3,4-dimethyl-5-isoxazolyl)-4'-(2-oxazolyl)-Ki0.0 [1], 10000.0 [2]
SparsentanKi0.8 [1]
Butyl N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-4-propylphenyl]sulfonylcarbamateIC501.5 [1]
N-[4-Oxo-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]quinazolin-6-yl]-N-pentylbenzamideIC501.7 [1], 7.0 [2]
N-[2-[4-[[3-Butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonylbenzamideIC502.5 [1]
N-[2-[4-[[3-Butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonylbenzamideKi1.7 [1]
3-Butyl-2-[2'-(1H-tetrazole-5-yl)-4-biphenylylmethyl]-2,3-diazaspiro[4.4]nonane-1,4-dioneKi25.0 [1]
7-Methyl-N-(2-phenylpropyl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-5-carboxamideIC500.9 [1], 16.7 [2]
Tert-butyl N-[2-[4-[[1-[2-bromo-5-(pentanoylamino)phenyl]-3-ethyl-5-oxo-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamateIC500.2 [1], 3.5 [2]
Unii-A9T9wvah03IC501.2 [1], 31.0 [2]
2,4-Bis(hydroxymethyl)-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrido[2,3-d]pyrimidin-7-oneIC5044.0 [1]
2-[4-[[4-Methyl-6-(2-phenylethylcarbamoyl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acidIC503.0 [1], 23.1 [2]
4-Methyl-7-oxo-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidine-2-carboxylic acidIC5011.0 [1], 23.0 [2]
2-(1,3-Benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-propylphenoxy]-N-(4-propan-2-ylphenyl)sulfonylacetamideIC5013.0 [1]
2-Propyl-5-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acidIC504.2 [1]
Tert-butyl N-[2-[4-[[3-butyl-1-[2-chloro-5-[(2-ethoxyacetyl)amino]phenyl]-5-oxo-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamateIC500.38 [1], 0.56 [2]
Tert-butyl N-[2-[4-[[3-butyl-5-oxo-1-[5-(pentanoylamino)-2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamateIC500.41 [1], 0.9 [2]
N-[2-[4-[[3-Butyl-5-oxo-1-[5-(propanoylamino)-2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonyl-2-chlorobenzamideIC500.25 [1], 0.43 [2]
3-[2-[4-[[2-Butyl-6-oxo-4-propan-2-yl-5-(2-pyrrolidin-1-yl-2-sulfanylideneethyl)pyrimidin-1-yl]methyl]phenyl]phenyl]-4H-1,2,4-oxadiazol-5-oneIC502.2 [1], 10.5 [2]
(2S)-2-[N-(4-Hydroxypentanoyl)-4-[2-(2H-tetrazol-5-yl)phenyl]anilino]-3-methylbutanoic acidIC500.47 [1]
(2S)-2-[N-(4-Hydroxypentanoyl)-4-[2-(2H-tetrazol-5-yl)phenyl]anilino]-3-methylbutanoic acidKi370.0 [1]
[Sar1,Bpa2]AngIIKi0.6 [1], 18.3 [2]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-3-(4-Benzoylphenyl)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi0.7 [1], 250.0 [2]
(2S)-2-[[(2S)-1-[(2S)-3-(4-Benzoylphenyl)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi31.6 [1], 500.0 [2]
(2S)-2-[[(2S)-3-(4-Benzoylphenyl)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoic acidKi12.8 [1], 500.0 [2]
[Tdf1]AngIIKi0.7 [1], 26.4 [2]
[Sar1,Tdf2]AngIIKi0.4 [1], 24.7 [2]
[Sar1,Tdf3]AngIIKi0.3 [1], 1.3 [2]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi0.5 [1], 250.0 [2]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi58.2 [1], 500.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoyl]amino]-3-phenylpropanoic acidKi3.8 [1], 500.0 [2]
[Bpa1]AngIIKi0.8 [1], 19.4 [2]
[Sar1,Bpa3]AngIIKi0.4 [1], 0.7 [2]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-3-(4-Benzoylphenyl)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi250.0 [1], 500.0 [2]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi250.0 [1], 500.0 [2]
[Sar1,Bpa8]AngIIKi0.6 [1], 0.8 [2]
[Sar1,Tdf8]AngIIKi0.7 [1], 0.9 [2]
2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,3-diazaspiro[4.4]nonane-6,9-dioneIC5022.0 [1]
2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,3-diazaspiro[4.4]nonane-6,9-dioneKi25.0 [1]
N-[2-[4-[(2-Butyl-6,9-dioxo-2,3-diazaspiro[4.4]nonan-3-yl)methyl]phenyl]phenyl]sulfonylbenzamideIC5012.0 [1]
N-[2-[4-[(2-Butyl-6,9-dioxo-2,3-diazaspiro[4.4]nonan-3-yl)methyl]phenyl]phenyl]sulfonylbenzamideKi10.0 [1]
(2-Benzoylphenyl)methyl 5-ethyl-3-[[2-fluoro-4-[2-(3-methylbutoxycarbonylsulfamoyl)phenyl]phenyl]methyl]-2-propylimidazole-4-carboxylateIC500.5 [1], 570.0 [2]
PropranololIC505011.87 [1]
Losartan potassiumIC505.5 [1]
FimasartanIC504.5 [1]
CID 121879IC503600.0 [1]
ZD 7155 hydrochlorideKi0.5 [1]
CipargaminIC5030000.0 [1]
PiboserodKi10000.0 [1]
Butyl N-[3-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamateIC501.1 [1]
ForasartanIC506.9 [1]
(Sar1,Ile8)-Angiotensin IIKi0.65 [1]
ZolasartanKi2.0 [1]
RipisartanKi24.0 [1]
EdonentanKi10.0 [1]
Potassium;2-[[5-ethyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3,4-thiadiazol-2-ylidene]carbamoyl]cyclopentene-1-carboxylateIC500.4 [1]
(6S)-1-[(4-Amino-3-methylphenyl)methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acidIC50100000.0 [1]
3-((2'-(Benzoylaminosulfonyl)biphenyl-4-yl)methyl)-2-ethyl-5,7-dimethyl-3H-imidazo(4,5-b)pyridineIC500.2 [1]
4-Ethyl-2-propyl-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylimidazole-5-carboxylic acidIC506.0 [1]
4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoateIC5079000.0 [1]
2-[4-[[2-Butyl-6-(cyclohexylcarbamoylamino)benzimidazol-1-yl]methyl]phenyl]benzoic acidKi29.0 [1]
2-[[4-[[2-Butyl-6-[methylcarbamoyl(pentyl)amino]benzimidazol-1-yl]methyl]phenyl]carbamoyl]-3,6-dichlorobenzoic acidKi20.0 [1]
CID 5311416Ki10000.0 [1]
6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl furan-2-carboxylateIC5079000.0 [1]
6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chloro-5-nitrobenzoateIC5079000.0 [1]
Butyl N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-4-[(3-methoxyphenyl)methyl]phenyl]sulfonylcarbamateIC501.4 [1]
Butyl N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-4-(2-methylpropyl)phenyl]sulfonylcarbamateIC502.1 [1]
6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-(pyrrolidin-1-ylsulfonyl)benzoateIC5079000.0 [1]
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoateIC5079000.0 [1]
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-(dimethylsulfamoyl)benzoateIC5079000.0 [1]
6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl benzoateIC5079000.0 [1]
4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 3-nitrobenzoateIC5079000.0 [1]
Butyl N-[3-[3-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamateKi10000.0 [1]
3-[2-Butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]quinazolin-6-yl]-1-methyl-1-propan-2-ylureaIC500.1 [1]
(E)-3-[2-Butyl-1-(2-chlorobenzyl)-1H-imidazol-5-yl]-2-(2-thienylmethyl)acrylic acidIC504530.0 [1]
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]pentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acidKi100000.0 [1]
4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(pyrrolidin-1-ylsulfonyl)benzoateIC5079000.0 [1]
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-(diethylsulfamoyl)benzoateIC5079000.0 [1]
Items per page: 1 - 10 of 100
⟨⟩

References

This online tool may be cited as follows

MLA

"Quest Database™ Type-1 angiotensin II receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/type-1-angiotensin-ii-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Type-1 angiotensin II receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/type-1-angiotensin-ii-receptor-inhibitors-ic50-ki.
BibTeXEndNoteRefMan
Location: Home / Datasets / Type-1 angiotensin II receptor Inhibitors (IC50, Ki)
AboutPrivacyTerms of UseTerms of SalesDistributors
Copyright © 2024 AAT Bioquest, Inc. All Rights Reserved.