 | Staurosporine | IC50 | 247.0 [1], 1250.0 [2] |
 | Ibrutinib | IC50 | 3.3 [1] |
 | Tyrphostin AG 808 | IC50 | 2320.0 [1], 53240.0 [2] |
 | [3-Fluoro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 10.0 [1], 54.0 [2] |
 | 5-{[(5-Bromo-2-methoxyphenyl)methylidene]amino}-2,3-dihydro-1H-1,3-benzodiazol-2-one | IC50 | 17110.0 [1], 100000.0 [2] |
 | N-[6-Methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-(piperidin-1-ylmethyl)-1,2-thiazol-5-amine | IC50 | 13.0 [1], 94.0 [2] |
 | CID 56675928 | IC50 | 2.0 [1], 5.0 [2] |
 | [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-morpholin-4-ylmethanone | IC50 | 30.0 [1], 52.0 [2] |
 | Tilfrinib | IC50 | 3.15 [1], 3.2 [2] |
 | 5-[(5-Chloro-2-hydroxy-3-methoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 1680.0 [1], 74040.0 [2] |
 | 5-[(5-Bromo-2-hydroxy-3-methoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 4730.0 [1], 52440.0 [2] |
 | 5-[(2-Hydroxy-5-iodo-3-methoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 4980.0 [1], 58100.0 [2] |
 | 2-(1,3-Benzothiazol-5-yliminomethyl)-3,4-dibromo-6-ethoxyphenol | IC50 | 1170.0 [1], 2540.0 [2] |
 | 2-(3H-Benzimidazol-5-yliminomethyl)-3,4-dibromo-6-ethoxyphenol | IC50 | 130.0 [1], 4710.0 [2] |
 | 5-[(2,3-Dichloro-5-ethoxy-6-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 1290.0 [1], 3480.0 [2] |
 | 5-[(2,3,5-Tribromo-6-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 410.0 [1], 11750.0 [2] |
 | 5-[(6-Bromo-2-hydroxy-3-methoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 3900.0 [1], 16630.0 [2] |
 | 5-[(2-Bromo-6-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 1350.0 [1], 24490.0 [2] |
 | 5-[(5-Chloro-3-ethoxy-2-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 1990.0 [1], 51250.0 [2] |
 | 3,4-Dibromo-6-ethoxy-2-(1H-indol-5-yliminomethyl)phenol | IC50 | 360.0 [1], 7580.0 [2] |
 | 2-(1,3-Benzothiazol-5-yliminomethyl)-3,4-dibromo-6-methoxyphenol | IC50 | 1300.0 [1], 4610.0 [2] |
 | 2-(3H-Benzimidazol-5-yliminomethyl)-3,4-dibromo-6-methoxyphenol | IC50 | 200.0 [1], 5520.0 [2] |
 | 3,4-Dibromo-2-(1H-indol-5-yliminomethyl)-6-methoxyphenol | IC50 | 270.0 [1], 3490.0 [2] |
 | 5-[(2-Hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 2000.0 [1], 100000.0 [2] |
 | 5-{[(E)-(3,5-Dibromo-2-hydroxyphenyl)methylidene]amino}-1,3-dihydro-2H-benzimidazol-2-one | IC50 | 5600.0 [1], 48960.0 [2] |
 | 5-{[(5-Bromo-2-hydroxyphenyl)methylidene]amino}-2,3-dihydro-1H-1,3-benzodiazol-2-one | IC50 | 1900.0 [1], 100000.0 [2] |
 | 5-[(5-Bromo-3-ethoxy-2-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 5830.0 [1], 23510.0 [2] |
 | [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-piperazin-1-ylmethanone | IC50 | 3.0 [1], 7.0 [2] |
 | (2,2-Dimethylpiperazin-1-yl)-[3-fluoro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]methanone | IC50 | 9.0 [1], 46.0 [2] |
 | [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-(2,2-dimethylpiperazin-1-yl)methanone | IC50 | 3.0 [1], 7.0 [2] |
 | [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-(3,3-dimethylpiperazin-1-yl)methanone | IC50 | 6.0 [1], 7.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(3,3-dimethylpiperazin-1-yl)methanone | IC50 | 18.0 [1], 19.0 [2] |
 | 6-Methyl-N-(5-piperazin-1-ylpyridin-3-yl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | IC50 | 75.0 [1], 244.0 [2] |
 | [4-[[6-Methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 15.0 [1], 167.0 [2] |
 | [2-Cyclopropyl-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 38.0 [1], 40.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4-methylpiperazin-1-yl)methanone | IC50 | 8.0 [1], 600.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4,7-diazaspiro[2.5]octan-4-yl)methanone | IC50 | 16.0 [1], 42.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]methanone | IC50 | 11.0 [1], 177.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4,7-diazaspiro[2.5]octan-4-yl)methanone | IC50 | 10.0 [1], 14.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone | IC50 | 13.0 [1], 33.0 [2] |
 | (3,3-Dimethylpiperazin-1-yl)-[3-fluoro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]methanone | IC50 | 10.0 [1], 38.0 [2] |
 | 1-[4-[2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]benzoyl]piperazin-1-yl]ethanone | IC50 | 16.0 [1], 3000.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-[(1R,4R)-2,5-diazabicyclo[2.2.2]octan-2-yl]methanone | IC50 | 5.0 [1], 45.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]methanone | IC50 | 10.0 [1], 17.0 [2] |
 | [2-Fluoro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 32.0 [1], 153.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4-hydroxypiperidin-1-yl)methanone | IC50 | 72.0 [1], 120.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-morpholin-4-ylmethanone | IC50 | 8.0 [1], 254.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(2,2-dimethylpiperazin-1-yl)methanone | IC50 | 10.0 [1], 23.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 256.0 [1], 3000.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(3,3-dimethylpiperazin-1-yl)methanone | IC50 | 3.0 [1], 47.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-morpholin-4-ylmethanone | IC50 | 124.0 [1], 600.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 7.0 [1], 157.0 [2] |
 | [4-[[6-Methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-2-(trifluoromethyl)phenyl]-piperazin-1-ylmethanone | IC50 | 7.0 [1], 35.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-[4-(2-hydroxyethyl)piperazin-1-yl]methanone | IC50 | 68.0 [1], 132.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(1,4-diazepan-1-yl)methanone | IC50 | 34.0 [1], 113.0 [2] |
 | [2-Chloro-4-[[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 6.0 [1], 22.0 [2] |
 | [2-Methoxy-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 22.0 [1], 23.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperidin-1-ylmethanone | IC50 | 93.0 [1], 608.0 [2] |
 | [2-Chloro-4-[[6-ethyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-piperazin-1-ylmethanone | IC50 | 10.0 [1], 38.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone | IC50 | 19.0 [1], 62.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-[(1R,4R)-2,5-diazabicyclo[2.2.2]octan-2-yl]methanone | IC50 | 7.0 [1], 47.0 [2] |
 | 6-Methyl-N-(2-piperazin-1-ylpyridin-4-yl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | IC50 | 11.0 [1], 109.0 [2] |
 | 4-[2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]benzoyl]piperazin-2-one | IC50 | 3.0 [1], 3000.0 [2] |
 | [2-Chloro-4-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]-(4-methoxypiperidin-1-yl)methanone | IC50 | 60.0 [1], 137.0 [2] |
 | N-(3-Chlorophenyl)-9H-pyrido[2,3-b]indol-4-amine | IC50 | 4.7 [1], 4.75 [2] |
 | 5-{[(E)-(5-Chloro-2-hydroxyphenyl)methylidene]amino}-1,3-dihydro-2H-benzimidazol-2-one | IC50 | 1410.0 [1], 100000.0 [2] |
 | 2-PropenaMide, N-[cis-4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]cyclohexyl]- | IC50 | 3.3 [1] |
 | Gefitinib | IC50 | 980.0 [1] |
 | Dasatinib | IC50 | 9.0 [1] |
 | Doramapimod | IC50 | 30000.0 [1] |
 | Lfm-a13 | IC50 | 267000.0 [1] |
 | Entrectinib | IC50 | 195.0 [1] |
 | CID 53469448 | IC50 | 412.0 [1] |
 | Nms-P937 (nms1286937) | IC50 | 10000.0 [1] |
 | CID 59604787 | IC50 | 10000.0 [1] |
 | 5-[2,4-Dihydroxy-6-(4-Nitrophenoxy)phenyl]-N-(1-Methylpiperidin-4-Yl)-1,2-Oxazole-3-Carboxamide | IC50 | 10.0 [1] |
 | (1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide | IC50 | 73.0 [1] |
 | Unii-BL7xsd8R7B | IC50 | 310.0 [1] |
 | 5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide | IC50 | 10000.0 [1] |
 | 2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide | IC50 | 10000.0 [1] |
 | 4-(4-Fluorophenyl)-5-pyridin-4-yl-2-(2,4,6-trichlorophenyl)pyrazol-3-amine | IC50 | 61.0 [1] |
 | 3-[(4-Morpholin-4-ylbenzoyl)amino]-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]-1H-thieno[3,2-c]pyrazole-5-carboxamide | IC50 | 10000.0 [1] |
 | Ripk1-IN-7 | IC50 | 111.0 [1] |
 | [6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate | IC50 | 50000.0 [1] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide | IC50 | 10000.0 [1] |
 | 1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)urea | IC50 | 30000.0 [1] |
 | N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide | IC50 | 50000.0 [1] |
 | 6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one | IC50 | 10000.0 [1] |
 | 2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one | IC50 | 10000.0 [1] |
 | 5-[(2,3-Dibromo-5-ethoxy-6-hydroxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 520.0 [1] |
 | 3-[[5-(1,3-Benzodioxol-5-yl)-[1,2,4]triazolo[1,5-c]quinazolin-8-yl]amino]propan-1-ol | IC50 | 10000.0 [1] |
 | 5-[(5-Bromo-2,3-dimethoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 10000.0 [1] |
 | 5-[(2,3-Dibromo-6-hydroxy-5-methoxyphenyl)methylamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 10000.0 [1] |
 | 5-[(2,3-Dibromo-5-ethoxy-6-hydroxyphenyl)methylamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 4790.0 [1] |
 | 5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide | IC50 | 10.0 [1] |
 | 5-[(2-Hydroxy-4-methoxyphenyl)methylideneamino]-1,3-dihydrobenzimidazol-2-one | IC50 | 10000.0 [1] |
 | 5-[2,4-Dihydroxy-6-[4-(propan-2-ylamino)phenoxy]phenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide | IC50 | 10.0 [1] |
 | 5-[2-[4-(Dimethylamino)phenoxy]-4,6-dihydroxyphenyl]-N-[1-(1,4-dioxaspiro[4.5]decan-8-yl)piperidin-4-yl]-1,2-oxazole-3-carboxamide | IC50 | 10.0 [1] |
 | 4-[8-Amino-3-[(3R)-1-(2-methylpropanoyl)piperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoro-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide | IC50 | 350.0 [1] |
 | 4-[8-Amino-3-[(2R)-4-(oxan-4-yl)morpholin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoro-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide | IC50 | 113.0 [1] |
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