Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	1-[5-(2,4-Difluoro-phenylsulfanyl)-4-nitro-thiophen-2-yl]-ethanone	IC50	8000.0 [1], 19330.0 [2]
	1-(5-(2,3-Dichlorophenylthio)-4-nitrothiophen-2-yl)ethanone	IC50	4200.0 [1]
	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile	IC50	420.0 [1]
	CID 73349008	IC50	28000.0 [1], 28100.0 [2]
	CID 122531786	IC50	750.0 [1], 980.0 [2]
	4-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]phenol	IC50	2500.0 [1], 4600.0 [2]
	1-(5-Phenylsulfanyl-4-nitro-2-thienyl)ethanone	IC50	31600.0 [1], 50000.0 [2]
	4-[2-Amino-4-ethyl-5-(1-methylindazol-5-yl)pyridin-3-yl]phenol	IC50	2000.0 [1], 63300.0 [2]
	Ursolic acid	IC50	7000.0 [1]
	Bardoxolone methyl	IC50	14080.0 [1]
	Xestoquinone	IC50	130.0 [1]
	Spongiacidin C	IC50	3800.0 [1]
	Methyl (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,11,12,14a,14b-dodecahydropicene-4a-carboxylate	IC50	25000.0 [1]
	5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide	IC50	1340.0 [1]
	USP7/USP47 inhibitor	IC50	420.0 [1]
	Chembl4128416	IC50	490.0 [1]
	3,5-Bis(4-hydroxyphenyl)pyridine	IC50	50000.0 [1]
	Chembl4127578	IC50	22570.0 [1]
	5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(4-methylphenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamide	IC50	3650.0 [1]
	5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(3-fluorophenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamide	IC50	1350.0 [1]
	1-[5-[(3,4-Dichlorophenyl)methylamino]-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	50000.0 [1]
	1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl acetate	IC50	50000.0 [1]
	1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl butanoate	IC50	4490.0 [1]
	5-(3,5-Dichloropyridin-4-yl)sulfanyl-N-[(4-fluorophenyl)methyl]-4-nitro-1,3-thiazole-2-carboxamide	IC50	2650.0 [1]
	1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanol	IC50	6950.0 [1]
	1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethyl benzoate	IC50	50000.0 [1]
	N-Benzyl-1-[5-(3,5-dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanamine	IC50	26780.0 [1]
	1-[5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	670.0 [1]
	1-[5-(3,4-Dimethoxyphenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	50000.0 [1]
	1-[5-(2,3-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	9930.0 [1]
	1-[5-(3,4-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	18020.0 [1]
	1-[5-(2,6-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	4490.0 [1]
	1-[5-(2,4-Dichlorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	16750.0 [1]
	1-[5-(3-Methoxyphenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	50000.0 [1]
	1-[5-(2,4-Difluorophenyl)sulfanyl-4-nitro-1,3-thiazol-2-yl]ethanone	IC50	6120.0 [1]
	N-Benzyl-5-(3,5-dichloropyridin-4-yl)sulfanyl-4-nitro-1,3-thiazole-2-carboxamide	IC50	4210.0 [1]
	5-(3,5-Dichloropyridin-4-yl)sulfanyl-4-nitro-N-phenyl-1,3-thiazole-2-carboxamide	IC50	40490.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-one	IC50	200.0 [1]
	4-[6-Amino-5-(4-hydroxyphenyl)-4-methylpyridin-3-yl]phenol	IC50	7600.0 [1]
	3-[2-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]benzonitrile	IC50	5200.0 [1]
	4-[6-Amino-5-(4-hydroxyphenyl)-4-propylpyridin-3-yl]phenol	IC50	13600.0 [1]
	3-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]benzonitrile	IC50	2500.0 [1]
	4-[6-Amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl]phenol	IC50	610.0 [1]
	4-[2-Amino-4-ethyl-5-(1H-indazol-6-yl)pyridin-3-yl]phenol	IC50	480.0 [1]
	4-[2-Amino-4-ethyl-5-(2-methylindazol-6-yl)pyridin-3-yl]phenol	IC50	63300.0 [1]
	4-[6-Amino-5-(4-hydroxyphenyl)-4-propan-2-ylpyridin-3-yl]phenol	IC50	21400.0 [1]
	CID 122531796	IC50	9600.0 [1]
	4-(6-Amino-4-ethyl-5-phenylpyridin-3-yl)phenol	IC50	22400.0 [1]
	Chembl4125949	IC50	130.0 [1]
	Chembl4127188	IC50	75.0 [1]
	Chembl4129261	IC50	100.0 [1]
	N-[3-[6-Amino-5-(4-hydroxyphenyl)pyridin-3-yl]phenyl]acetamide	IC50	15100.0 [1]
	3-[4-(Aminomethyl)phenyl]-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	6.0 [1]
	7-Bromo-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	IC50	300.0 [1]
	7-Bromo-3-[[4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	IC50	46000.0 [1]
	7-Bromo-3-[[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	IC50	13000.0 [1]
	3-Bromo-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	300.0 [1]
	Usp7-IN-3	IC50	22.0 [1]
	Usp7-IN-4	IC50	2400.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-pyrrolidin-1-ylethylamino)pyrimidin-4-one	IC50	90.0 [1]
	6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-propan-2-ylpyrazolo[4,3-d]pyrimidin-7-one	IC50	560.0 [1]
	3-(2-Fluorophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	90.0 [1]
	6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-phenylpyrazolo[4,3-d]pyrimidin-7-one	IC50	30.0 [1]
	3-(3-Hydroxyphenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	39.0 [1]
	3-[4-(Hydroxymethyl)phenyl]-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	40.0 [1]
	6-Anilino-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	1900.0 [1]
	6-[2-(Dimethylamino)ethylamino]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	120.0 [1]
	3-Ethynyl-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	240.0 [1]
	6-[2-(Dimethylamino)ethoxy]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	7200.0 [1]
	3-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzamide	IC50	30.0 [1]
	3-(3-Hydroxy-3-methylbut-1-ynyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	300.0 [1]
	6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	44000.0 [1]
	6-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]-2-methylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-one	IC50	130000.0 [1]
	3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[3,2-d]pyrimidin-4-one	IC50	115000.0 [1]
	3-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzonitrile	IC50	150.0 [1]
	3-(2-Aminophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	1400.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	23000.0 [1]
	6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-[3-(morpholin-4-ylmethyl)phenyl]pyrazolo[4,3-d]pyrimidin-7-one	IC50	250.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-phenylethynyl)pyrimidin-4-one	IC50	2800.0 [1]
	3-[[4-Hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]furo[2,3-d]pyrimidin-4-one	IC50	87000.0 [1]
	6-[2-(Dimethylamino)ethyl-methylamino]-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	390.0 [1]
	6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-(1H-pyrazol-5-yl)pyrazolo[4,3-d]pyrimidin-7-one	IC50	35.0 [1]
	3-(3-Aminophenyl)-6-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methylpyrazolo[4,3-d]pyrimidin-7-one	IC50	24.0 [1]
	6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-3-prop-1-en-2-ylpyrazolo[4,3-d]pyrimidin-7-one	IC50	330.0 [1]
	6-Benzyl-3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]pyrimidin-4-one	IC50	90000.0 [1]
	CID 135567363	IC50	79200.0 [1]
	4-(3-Pyrrolidin-3-yl-1,2,4-oxadiazol-5-yl)phenol	IC50	132000.0 [1]
	4-(3-Piperidin-4-yl-1,2,4-oxadiazol-5-yl)phenol	IC50	97700.0 [1]
	4-(4-Piperidin-4-yl-1,3-oxazol-2-yl)phenol	IC50	85200.0 [1]
	4-[2,6-Diamino-5-(4-hydroxyphenyl)pyridin-3-yl]phenol	IC50	8500.0 [1]
	2-Amino-3,5-bis(4-hydroxyphenyl)pyridine-4-carbonitrile	IC50	200000.0 [1]
	4-[3-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazol-5-yl]phenol	IC50	131000.0 [1]
	3-Fluoro-4-(5-piperidin-4-yl-1,3-oxazol-2-yl)phenol	IC50	18400.0 [1]
	4-[2-Amino-5-(2-chlorophenyl)pyridin-3-yl]phenol	IC50	33200.0 [1]
	4-[6-Amino-5-(4-hydroxyphenyl)pyridin-3-yl]phenol	IC50	11100.0 [1]
	4-(5-Piperidin-4-yl-1,3-oxazol-2-yl)phenol	IC50	32800.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(methylamino)pyrimidin-4-one	IC50	4200.0 [1]
	3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-methoxyethylamino)pyrimidin-4-one	IC50	12000.0 [1]
	7-Cyclopropyl-3-[[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	IC50	20000.0 [1]
	4-[6-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]benzamide	IC50	50.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/ubiquitin-carboxyl-terminal-hydrolase-7-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Ubiquitin carboxyl-terminal hydrolase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/ubiquitin-carboxyl-terminal-hydrolase-7-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan