Vascular endothelial growth factor receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Vandetanib	IC50	25.0 [1], 400.0 [2]
	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[2-(triazol-1-yl)ethoxy]quinazolin-4-amine	IC50	50.0 [1]
	6-(4-Methoxyphenyl)-3-(3-thienyl)-pyrazolo(1,5-a)pyrimidine	IC50	387.0 [1]
	Pyrazolo[1,5-a]pyrimidine 1a	IC50	622.0 [1]
	Pyrazolo[1,5-a]pyrimidine 2c	IC50	150.0 [1]
	Erlotinib	IC50	250.0 [1]
	Vatalanib	IC50	100.0 [1]
	PD173074	IC50	190.0 [1]
	Raf265(chir-265)	IC50	20.0 [1]
	PDGF Receptor Tyrosine Kinase Inhibitor IV	IC50	3100.0 [1]
	N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine	IC50	1000.0 [1]
	N-(4-Chlorophenylsulfonyl)benzamide	IC50	22000.0 [1]
	4-[2-[4-(3-Phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine	IC50	32.0 [1]
	2-Oxazolamine, N,5-diphenyl-	IC50	3000.0 [1]
	N-[2,4-Dichlorobenzoyl]phenylsulfonamide	IC50	530.0 [1]
	2,4-Dichloro-N-(4-chlorophenyl)sulfonylbenzamide	IC50	170.0 [1]
	4-[2-(3-Tert-butylanilino)-1-methylbenzimidazol-5-yl]oxy-N-methylpyridine-2-carboxamide	IC50	5.0 [1]
	N-[5-(Ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine	IC50	370.0 [1]
	N-(3-Methylphenyl)-5-phenyl-1,3-oxazol-2-amine	IC50	1700.0 [1]
	4-[(5-Phenyl-1,3-oxazol-2-yl)amino]benzenesulfonamide	IC50	4660.0 [1]
	N-(3,5-Dimethoxyphenyl)-5-phenyl-1,3-oxazol-2-amine	IC50	1690.0 [1]
	5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,3-oxazol-2-amine	IC50	420.0 [1]
	2-Anilino-5-aryloxazole 20	IC50	1310.0 [1]
	2-Anilino-5-aryloxazole 24	IC50	7600.0 [1]
	2-Anilino-5-aryloxazole 27	IC50	1650.0 [1]
	2-Anilino-5-aryloxazole 28	IC50	350.0 [1]
	1-[3-(2-{[5-(Ethylsulfonyl)-2-methoxyphenyl]amino}-1,3-oxazol-5-yl)phenyl]ethanone	IC50	13900.0 [1]
	2-Anilino-5-aryloxazole 44	IC50	40.0 [1]
	Unii-8FX9DP2Y1W	IC50	1000.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-(5-methyl-1,3,4-oxadiazol-2-yl)-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	7.6 [1]
	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(2-methoxyethoxy)quinazolin-4-amine	IC50	40.0 [1]
	Pyrazolo[1,5-a]pyrimidine 4e	IC50	18.0 [1]
	4-[2-[4-(3-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine	IC50	31.0 [1]
	3-[[5-[6-[(3-Chlorophenyl)amino]pyrazinyl]-3-pyridinyl]amino]-1-propanol	IC50	5.0 [1]
	5-[[6-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2,4-difluoro-N-methoxybenzamide	IC50	17.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-(5-methyl-1,3-oxazol-2-yl)-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	1.1 [1]
	2,4-Difluoro-N-methoxy-5-[[6-[5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	2.1 [1]
	2,4-Dichloro-N-(3,4-dichlorophenyl)sulfonylbenzamide	IC50	460.0 [1]
	(3-Chloro-4-fluoro-phenyl)-(5-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-yl)-amine	IC50	2500000.0 [1]
	5-[[6-[5-[Difluoro(methylsulfonyl)methyl]-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2,4-difluoro-N-methoxybenzamide	IC50	27.0 [1]
	1-(3-Cyanophenyl)-3-(4,6,8,9-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)urea	IC50	200.0 [1]
	1-(4-Fluorophenyl)-3-(4,6,8,9-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)urea	IC50	631.0 [1]
	1-(4,6,8,9-Tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)-3-[4-(trifluoromethyl)phenyl]urea	IC50	3980.0 [1]
	1-(4,6,8,9-Tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)-3-[3-(trifluoromethyl)phenyl]urea	IC50	251.0 [1]
	1-(3-Nitrophenyl)-3-(4,6,8,9-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)urea	IC50	10000.0 [1]
	1-(4-Bromophenyl)-3-(4,6,8,9-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,7,10,12-hexaen-3-yl)urea	IC50	3980.0 [1]
	Vandetanib hydrochloride	IC50	60.0 [1]
	1,6-Naphthyridine deriv. 20	IC50	37.0 [1]
	Anilinoquinazoline deriv. 21	IC50	300.0 [1]
	Anilinoquinazoline deriv. 22	IC50	50.0 [1]
	Anilinoquinazoline deriv. 28	IC50	200.0 [1]
	3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3f	IC50	328.0 [1]
	2,4-Disubstituted Pyrimidine 2d	IC50	19.0 [1]
	Pyrazolo[1,5-a]pyrimidine 4a	IC50	22.0 [1]
	Pyrazolo[1,5-a]pyrimidine 4g	IC50	29.0 [1]
	N-[4-[2-(3-Tert-butylanilino)-1-methylbenzimidazol-5-yl]oxypyridin-2-yl]acetamide	IC50	2.0 [1]
	2-Methyl-5-(pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol	IC50	360000.0 [1]
	4-Bromo-2-chloro-N-(4-chlorophenyl)sulfonylbenzamide	IC50	200.0 [1]
	2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol	IC50	213000.0 [1]
	2-Methyl-5-(7-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol	IC50	477000.0 [1]
	5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-2-methyl-phenol	IC50	310000.0 [1]
	3-Piperidin-1-ylpropyl N-[4-[2,4-difluoro-5-(methoxycarbamoyl)anilino]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate	IC50	62.0 [1]
	5-[[6-[5-(Cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2,4-difluoro-N-methoxybenzamide	IC50	4.0 [1]
	N-(4-Chlorophenyl)sulfonyl-4-(dimethylamino)benzamide	IC50	16000.0 [1]
	2,4-Dichloro-N-(4-methoxyphenyl)sulfonylbenzamide	IC50	350.0 [1]
	2,4-Dichloro-N-(3-methoxyphenyl)sulfonylbenzamide	IC50	910.0 [1]
	3-Chloro-N-(4-chlorophenyl)sulfonylbenzamide	IC50	14000.0 [1]
	2,4-Dichloro-N-(3-chloro-4-fluorophenyl)sulfonylbenzamide	IC50	410.0 [1]
	2,5-Dichloro-N-(4-chlorophenyl)sulfonylbenzamide	IC50	13000.0 [1]
	4-Chloro-N-(4-chlorophenyl)sulfonyl-2-propylbenzamide	IC50	1300.0 [1]
	2,4-Dibromo-N-(4-chlorophenyl)sulfonylbenzamide	IC50	250.0 [1]
	4-Chloro-N-(4-chlorophenyl)sulfonyl-2-nitrobenzamide	IC50	5900.0 [1]
	2,4-Dichloro-N-(3,4-dimethoxyphenyl)sulfonylbenzamide	IC50	3900.0 [1]
	2,4-Dichloro-N-(3,5-dichlorophenyl)sulfonylbenzamide	IC50	1400.0 [1]
	4-Bromo-N-(4-chlorophenyl)sulfonyl-2-methylbenzamide	IC50	610.0 [1]
	N-(3-Bromophenyl)sulfonyl-2,4-dichlorobenzamide	IC50	250.0 [1]
	N-(4-Acetylphenyl)sulfonyl-2,4-dichlorobenzamide	IC50	560.0 [1]
	2,4-Dichloro-N-[4-(dimethylamino)phenyl]sulfonylbenzamide	IC50	930.0 [1]
	2,4-Dichloro-N-(3-nitrophenyl)sulfonylbenzamide	IC50	910.0 [1]
	N-(4-Chlorophenyl)sulfonyl-2-nitro-4-(trifluoromethyl)benzamide	IC50	11000.0 [1]
	N-(2-Methoxyphenyl)-5-phenyl-1,3-oxazol-2-amine;hydrochloride	IC50	3260.0 [1]
	4-Chloro-N-(4-chlorophenyl)sulfonyl-2-methoxybenzamide	IC50	2000.0 [1]
	2-Chloro-N-(4-chlorophenyl)sulfonyl-4-nitrobenzamide	IC50	620.0 [1]
	N-(3,4-Dimethoxyphenyl)-5-phenyl-1,3-oxazol-2-amine;hydrochloride	IC50	1130.0 [1]
	2,4-Dichloro-N-(4-methylphenyl)sulfonylbenzamide	IC50	210.0 [1]
	2,4-Dichloro-N-(3-chlorophenyl)sulfonylbenzamide	IC50	440.0 [1]
	3-Bromo-N-(4-chlorophenyl)sulfonylbenzamide	IC50	15000.0 [1]
	2,4-Dichloro-N-(3-chloro-4-methylphenyl)sulfonylbenzamide	IC50	360.0 [1]
	2,4-Dichloro-N-(3,4-dibromophenyl)sulfonylbenzamide	IC50	910.0 [1]
	4-Chloro-N-(4-chlorophenyl)sulfonyl-2-ethylbenzamide	IC50	630.0 [1]
	N-(4-Chlorophenyl)sulfonyl-2-methylbenzamide	IC50	15000.0 [1]
	N-(4-Chlorophenyl)sulfonyl-2,4-dimethoxybenzamide	IC50	20000.0 [1]
	N-(3-Chloro-4-fluorophenyl)-7-methylpyrrolo[2,1-f][1,2,4]triazin-4-amine	IC50	2500000.0 [1]
	N-(2-Bromo-4-methylphenyl)sulfonyl-2,4-dichlorobenzamide	IC50	20000.0 [1]
	N-(4-Chlorophenyl)sulfonyl-2,4-dinitrobenzamide	IC50	13000.0 [1]
	2-Amino-4-chloro-N-(4-chlorophenyl)sulfonylbenzamide	IC50	3200.0 [1]
	2,4-Dichloro-N-(2-chlorophenyl)sulfonylbenzamide	IC50	14000.0 [1]
	Ethyl N-[4-[2,4-difluoro-5-(methoxycarbamoyl)anilino]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate	IC50	31.0 [1]
	(1-Methylpiperidin-4-yl) N-[4-[2,4-difluoro-5-(methoxycarbamoyl)anilino]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate	IC50	19.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-(5-methyl-1H-1,2,4-triazol-3-yl)-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	50.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Vascular endothelial growth factor receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/vascular-endothelial-growth-factor-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Vascular endothelial growth factor receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/vascular-endothelial-growth-factor-receptor-inhibitors-ic50-ki.
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