 | Lixivaptan | IC50 | 1.0 [1], 1.2 [2], 5.0 [3], 91.0 [4] |
| Lixivaptan | Ki | 2.3 [1], 23.0 [2], 90.0 [3] |
 | Argipressin | IC50 | 242.0 [1] |
| Argipressin | Ki | 1.2 [1], 1.36 [2], 1.48 [3], 32.0 [4] |
 | Way-vna-932 | IC50 | 80.0 [1], 80.3 [2] |
| Way-vna-932 | Ki | 39.9 [1], 50.0 [2] |
 | 2-Phenyl-4'-[(2,3,4,5-tetrahydro-1H-1-benzoazepine-1-yl)carbonyl]benzanilide | IC50 | 0.57 [1] |
| 2-Phenyl-4'-[(2,3,4,5-tetrahydro-1H-1-benzoazepine-1-yl)carbonyl]benzanilide | Ki | 0.57 [1], 7.5 [2] |
 | Cligosiban | IC50 | 1530.0 [1], 2620.0 [2] |
| Cligosiban | Ki | 10000.0 [1] |
 | 2-(4-Fluoro-2-methylphenyl)-5-[4-(6-methoxypyridin-3-yl)-5-methyl-1,2,4-triazol-3-yl]pyrazine | Ki | 10000.0 [1] |
 | 1-[4-[(5-Fluoro-2-methylbenzoyl)amino]benzoyl]-N-(2-piperidin-1-ylethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 8.0 [1], 9.0 [2], 39.0 [3], 48.0 [4] |
 | Oxytocin | Ki | 1544.0 [1], 3500.0 [2], 6000.0 [3] |
 | Quercetin | IC50 | 6309.57 [1], 15848.93 [2], 39810.72 [3] |
 | Sporanox | IC50 | 794.33 [1], 6309.57 [2], 12589.25 [3] |
 | Mozavaptan | IC50 | 500.0 [1] |
| Mozavaptan | Ki | 9.42 [1], 9.7 [2] |
 | 1-(1-(4-(3-Acetylaminopropoxy)benzoyl)-4-piperidyl)-3,4-dihydro-2(1H)-quinolinone | Ki | 10000.0 [1], 81000.0 [2] |
 | Nelivaptan | Ki | 290.0 [1], 325.0 [2] |
 | CID 6918320 | Ki | 37000.0 [1] |
 | Clotrimazole | IC50 | 2511.89 [1], 15848.93 [2] |
 | Conivaptan | IC50 | 11.0 [1] |
| Conivaptan | Ki | 0.36 [1] |
 | Unii-ER33G946JT | Ki | 590.0 [1] |
 | CID 3038506 | IC50 | 330.0 [1] |
| CID 3038506 | Ki | 91.9 [1] |
 | 4-[(3,5-Dihydroxyphenyl)methyl]-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]piperazine-1-carboxamide | Ki | 58.4 [1], 1000.0 [2] |
 | Unii-4V7CN33O10 | IC50 | 34.0 [1], 52.0 [2] |
 | (2S)-2-(4-Methyl-1,4-diazepane-1-carbothioyl)-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]pyrrolidine-1-carboxamide | Ki | 1000.0 [1] |
 | CID 6918854 | Ki | 630.96 [1] |
 | 1-[1-[2-[2-(2-Fluoroethoxy)-4-(1-methylsulfonylpiperidin-4-yl)oxyphenyl]acetyl]piperidin-4-yl]-3,4-dihydroquinolin-2-one | Ki | 1800.0 [1] |
 | (2-Chloro-4-pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-methanone | IC50 | 9.0 [1] |
 | (2R)-2-[(2R,5R)-5-(2,3-Dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-2-(4-fluorophenyl)-N-propan-2-ylacetamide | Ki | 1258.93 [1] |
 | (2R)-2-[(2R,5R)-5-(2,3-Dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-2-[4-(dimethylamino)phenyl]-N-propan-2-ylacetamide | Ki | 79432.82 [1] |
 | 2,4-Dichloro-N-[4-(6,11-dihydropyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]benzamide | IC50 | 3.2 [1] |
 | (4-Amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-methanone | IC50 | 4.1 [1], 18.0 [2] |
 | 1H-1-Benzazepine, 1-(4-aminobenzoyl)-2,3,4,5-tetrahydro- | IC50 | 180.0 [1] |
| 1H-1-Benzazepine, 1-(4-aminobenzoyl)-2,3,4,5-tetrahydro- | Ki | 1000.0 [1] |
 | 2-(N-(4-Ethoxyphenyl)sulfonyl-4-methylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide | Ki | 2500.0 [1] |
 | (2R)-2-(2,4-Difluorophenyl)-2-[(2R,5R)-5-(2,3-dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-N,N-dimethylacetamide | Ki | 39.81 [1], 316.23 [2] |
 | 1-[4-(2-Methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine | Ki | 2.68 [1], 7.2 [2] |
 | [2-Chloro-4-(3-methylpyrazol-1-yl)phenyl]-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepin-5-yl)methanone | Ki | 29.0 [1] |
 | (2Z)-2-[1-[2-Chloro-4-(3-methylpyrazol-1-yl)benzoyl]-4,4-difluoro-2,3-dihydro-1-benzazepin-5-ylidene]-N-(2-hydroxyethyl)acetamide | Ki | 9.7 [1] |
 | 5-[3-(Ethoxymethyl)-5-(4-ethoxy-3-methylphenyl)-1,2,4-triazol-4-yl]-2-methoxypyridine | Ki | 10000.0 [1] |
 | N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-(trifluoromethyl)benzamide | IC50 | 7.0 [1] |
| N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-(trifluoromethyl)benzamide | Ki | 9.0 [1] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl]phenyl]-2-phenylbenzamide | Ki | 3.2 [1], 15.0 [2] |
 | N-[2-(Dimethylamino)ethyl]-1-[4-[(2-phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 11.0 [1], 100.0 [2] |
 | (4R)-1-[4-[(2-Chloro-5-fluorobenzoyl)amino]-3-ethoxybenzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid | IC50 | 71.0 [1], 150.0 [2] |
 | 1-[4-[(2-Chloro-5-fluorobenzoyl)amino]-3-methoxybenzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid | IC50 | 92.0 [1], 120.0 [2] |
 | (4R)-1-[4-[(2-Chloro-5-fluorobenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid | IC50 | 53.0 [1], 100.0 [2] |
 | N-[3-Chloro-4-[(12R)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4,6,8-triene-10-carbonyl]phenyl]-2-phenylbenzamide | IC50 | 15.0 [1] |
| N-[3-Chloro-4-[(12R)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4,6,8-triene-10-carbonyl]phenyl]-2-phenylbenzamide | Ki | 30.0 [1] |
 | (10R,13S,16S,19S)-N-[(2S)-1-[[(2R)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-19-(2-amino-2-oxoethyl)-13-benzyl-10-[(4-ethoxyphenyl)methyl]-8,11,14,17,20-pentaoxo-16-propan-2-yl-9,12,15,18,21-pentazaspiro[5.19]pentacosane-22-carboxamide | Ki | 400000.0 [1], 3900000.0 [2] |
 | N-[3-Chloro-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-3-methylpyrazole-1-carboxamide | IC50 | 13.0 [1] |
| N-[3-Chloro-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-3-methylpyrazole-1-carboxamide | Ki | 38.0 [1] |
 | 1-[4-[(2-Phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid | IC50 | 14.0 [1], 360.0 [2] |
 | 1-[4-[(5-Fluoro-2-methylbenzoyl)amino]-2-methoxybenzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid | IC50 | 110.0 [1], 140.0 [2] |
 | 1-[4-[(5-Fluoro-2-methylbenzoyl)amino]benzoyl]-N-(2-pyrrolidin-1-ylethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 39.0 [1], 48.0 [2] |
 | N-[4-[1'-(Hydroxymethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1-carbonyl]phenyl]-2-phenylbenzamide | IC50 | 18.0 [1], 190.0 [2] |
 | N-[4-[1'-(Methylaminomethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1-carbonyl]phenyl]-2-phenylbenzamide | IC50 | 44.0 [1], 1800.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]phenyl]-2-phenylbenzamide | Ki | 3.7 [1], 16.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-5-fluoro-2-methylbenzamide | Ki | 2.8 [1], 12.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-4-fluoro-2-phenylbenzamide | Ki | 1.9 [1], 2.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-4-methoxy-2-phenylbenzamide | Ki | 4.2 [1], 5.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-5-fluoro-2-phenylbenzamide | Ki | 11.0 [1], 12.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-2-(4-hydroxyphenyl)benzamide | Ki | 4.2 [1], 11.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-2-(3-hydroxyphenyl)benzamide | Ki | 5.0 [1], 20.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-2-(4-methoxyphenyl)benzamide | Ki | 2.8 [1], 3.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-2-(3-methoxyphenyl)benzamide | Ki | 2.0 [1], 3.7 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-4-hydroxy-2-phenylbenzamide | Ki | 1.4 [1], 6.0 [2] |
 | N-[4-[(4As)-1,2,4,4a,5,11-hexahydro-[1,4]oxazino[3,4-c][1,4]benzodiazepine-6-carbonyl]-3-chlorophenyl]-5-hydroxy-2-phenylbenzamide | Ki | 13.0 [1], 70.0 [2] |
 | N-[4-(8-Methyl-1,2,4,4a,5,11-hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl)phenyl]-2-phenylbenzamide | Ki | 8.0 [1], 23.0 [2] |
 | N-[4-[(4Ar)-1,2,4,4a,5,11-hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl]phenyl]-2-phenylbenzamide | Ki | 25.0 [1], 40.0 [2] |
 | N-[4-(3,3-Dioxo-1,2,4,4a,5,11-hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl)phenyl]-2-phenylbenzamide | Ki | 40.0 [1], 65.0 [2] |
 | N-[4-(1,2,4,4a,5,11-Hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl)-3-chlorophenyl]-5-fluoro-2-phenylbenzamide | Ki | 37.0 [1], 70.0 [2] |
 | N-[4-(1,2,4,4a,5,11-Hexahydro-[1,4]thiazino[3,4-c][1,4]benzodiazepine-6-carbonyl)-3-chlorophenyl]-5-fluoro-2-methylbenzamide | Ki | 60.0 [1], 300.0 [2] |
 | N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-(4-methylphenyl)benzamide | IC50 | 5.0 [1] |
| N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-(4-methylphenyl)benzamide | Ki | 13.0 [1] |
 | 2-Chloro-N-[4-[(12S)-6-chloro-2,10-diazatetracyclo[11.2.2.02,12.04,9]heptadeca-4(9),5,7-triene-10-carbonyl]phenyl]benzamide | IC50 | 13.0 [1] |
| 2-Chloro-N-[4-[(12S)-6-chloro-2,10-diazatetracyclo[11.2.2.02,12.04,9]heptadeca-4(9),5,7-triene-10-carbonyl]phenyl]benzamide | Ki | 520.0 [1] |
 | 2-Chloro-N-[4-[(12S)-6-chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]benzamide | IC50 | 10.0 [1] |
| 2-Chloro-N-[4-[(12S)-6-chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]benzamide | Ki | 32.0 [1] |
 | 2-Methyl-N-[4-(1,2,3,4-tetrahydro-1,5-benzodiazepine-5-carbonyl)phenyl]benzamide | IC50 | 28.0 [1] |
| 2-Methyl-N-[4-(1,2,3,4-tetrahydro-1,5-benzodiazepine-5-carbonyl)phenyl]benzamide | Ki | 160.0 [1] |
 | N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-fluorobenzamide | IC50 | 26.0 [1] |
| N-[4-[(12S)-6-Chloro-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-triene-10-carbonyl]phenyl]-2-fluorobenzamide | Ki | 180.0 [1] |
 | N-[3-(Dimethylamino)propyl]-1-[4-[(5-fluoro-2-methylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 23.0 [1], 31.0 [2] |
 | 1-[4-[(2-Fluorobenzoyl)amino]benzoyl]-N-(2-piperidin-1-ylethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 1000.0 [1] |
 | 1-[4-[(2-Fluorobenzoyl)amino]benzoyl]-N-(2-pyrrolidin-1-ylethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 1000.0 [1] |
 | N-[2-(Dimethylamino)ethyl]-1-[4-[(5-fluoro-2-methylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 20.0 [1], 105.0 [2] |
 | Methyl 2-[[1-[4-[(5-fluoro-2-methylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carbonyl]amino]acetate | IC50 | 10.0 [1], 440.0 [2] |
 | N-(2-Hydroxyethyl)-1-[4-[(2-phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 11.0 [1], 170.0 [2] |
 | 2-[[1-[4-[(2-Phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carbonyl]amino]acetic acid | IC50 | 18.0 [1], 350.0 [2] |
 | N-[3-(Dimethylamino)propyl]-1-[4-[(2-phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 16.0 [1], 20.0 [2] |
 | 1-[4-[(2-Fluorobenzoyl)amino]benzoyl]-N-(2-hydroxyethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide | IC50 | 1000.0 [1] |
 | 2-[(2R)-5-[4-[(2-Phenylbenzoyl)amino]benzoyl]-3,4-dihydro-2H-1,5-benzothiazepin-2-yl]acetic acid | IC50 | 7.0 [1], 36.0 [2] |
 | 3-[(2R)-5-[4-[(2-Phenylbenzoyl)amino]benzoyl]-3,4-dihydro-2H-1,5-benzothiazepin-2-yl]propanoic acid | IC50 | 16.0 [1], 40.0 [2] |
 | N-[4-[2-(2-Hydroxyethyl)-3,4-dihydro-2H-1,5-benzothiazepine-5-carbonyl]phenyl]-2-phenylbenzamide | IC50 | 8.0 [1], 100.0 [2] |
 | 3-[(2S)-5-[4-[(2-Phenylbenzoyl)amino]benzoyl]-3,4-dihydro-2H-1,5-benzothiazepin-2-yl]propanoic acid | IC50 | 15.0 [1], 30.0 [2] |
Calculator
