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Vitronectin receptor alpha Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-[(2S,5S,11S,14R)-14-Benzyl-11-(carboxymethyl)-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]butanoic acidIC5038800.0 [1]
3-[1-Oxo-6-(1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-9-yloxy)-3,4-dihydroisoquinolin-2-yl]-3-pyridin-3-ylpropanoic acidIC505.0 [1]
3-(1,3-Benzodioxol-5-yl)-3-[1-oxo-6-(1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-9-yloxy)-3,4-dihydroisoquinolin-2-yl]propanoic acidIC5014.0 [1]
3-[1-Oxo-6-(1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-9-yloxy)-3,4-dihydroisoquinolin-2-yl]propanoic acidIC50310.0 [1]
3-(4-(2-Amino-1-methyl-1H-benzo[d]imidazol-4-yloxy)benzamido)propanoic acidIC502050.0 [1]
3-(5-(2-Amino-1-methyl-1H-benzo[d]imidazol-4-yloxy)-1-oxoisoindolin-2-yl)propanoic acidIC504800.0 [1]
3-[6-(2-Amino-1-methylbenzimidazol-4-yl)oxy-1-oxo-3,4-dihydroisoquinolin-2-yl]propanoic acidIC50600.0 [1]
3-[7-(2-Amino-1-methylbenzimidazol-4-yl)oxy-1-oxo-4,5-dihydro-3H-2-benzazepin-2-yl]propanoic acidIC504300.0 [1]
(2R)-3-(Thiophene-3-carbonylamino)-2-[(2,4,6-trichlorophenyl)sulfonylamino]propanoic acidIC5024.0 [1]
(2R)-3-(Furan-3-carbonylamino)-2-[(3-methoxyphenyl)sulfonylamino]propanoic acidIC50208.0 [1]
(R)-3-(Furan-3-carboxamido)-2-(pyridine-3-sulfonamido)propanoic acidIC50793.0 [1]
(2R)-3-[[2-(Furan-3-yl)-2-oxoethyl]amino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC508000.0 [1]
(2R)-3-(Methanesulfonamido)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-3-[(2-Phenylacetyl)amino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-3-(Thiophene-3-carbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5044.0 [1]
(2R)-3-(Furan-3-carbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5032.0 [1]
(2R)-3-Benzamido-2-[(2-chlorophenyl)sulfonylamino]propanoic acidIC50260.0 [1]
(2R)-3-Benzamido-2-[(2-methoxyphenyl)sulfonylamino]propanoic acidIC50729.0 [1]
(2R)-3-(3-Oxo-1H-isoindol-2-yl)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC50975.0 [1]
(2R)-3-[(2-Methoxybenzoyl)amino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5078.0 [1]
(2R)-3-(Furan-3-carbonylamino)-2-[(2-methylphenyl)sulfonylamino]propanoic acidIC50260.0 [1]
(2R)-3-Benzamido-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC50120.0 [1]
(2R)-3-Acetamido-2-(benzenesulfonamido)propanoic acidIC509100.0 [1]
(2R)-3-(Pyridine-3-carbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5081.0 [1]
(2R)-3-Benzamido-2-[(2-iodophenyl)sulfonylamino]propanoic acidIC5025.0 [1]
(2R)-3-Benzamido-2-[(2,6-dichlorophenyl)sulfonylamino]propanoic acidIC50118.0 [1]
(2R)-2-[(3-Cyanophenyl)sulfonylamino]-3-(furan-3-carbonylamino)propanoic acidIC5098.0 [1]
(2R)-3-(Methoxycarbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2S)-3-Acetamido-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC508000.0 [1]
(2R)-3-Benzamido-2-[(2-methylsulfonylphenyl)sulfonylamino]propanoic acidIC504600.0 [1]
(2R)-3-(Furan-3-carbonylamino)-2-[(2-methoxyphenyl)sulfonylamino]propanoic acidIC50700.0 [1]
(R)-3-Acetamido-2-(tert-butoxycarbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-Acetamido-2-[methyl-(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-2-[(2,4-Dichlorophenyl)sulfonylamino]-3-(thiophene-3-carbonylamino)propanoic acidIC508.0 [1]
(2R)-3-Amino-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-3-(Butanoylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5030000.0 [1]
(2R)-3-[(2-Methylpropan-2-yl)oxycarbonylamino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-3-(Benzylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5050000.0 [1]
(2R)-3-Acetamido-2-(benzylsulfonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-[(2-Methyl-1,3-oxazole-4-carbonyl)amino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5041.0 [1]
(2R)-3-Benzamido-2-[(2-methylphenyl)sulfonylamino]propanoic acidIC50320.0 [1]
(2R)-3-Benzamido-2-[(2,3-dichlorophenyl)sulfonylamino]propanoic acidIC5062.0 [1]
(2R)-3-Acetamido-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC50800.0 [1]
(R)-3-Acetamido-2-(2,6-dichlorobenzamido)propanoic acidIC5050000.0 [1]
(R)-3-Acetamido-2-benzamidopropanoic acidIC5050000.0 [1]
(R)-3-Acetamido-2-(phenoxycarbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-[(2-Methylpyrazole-3-carbonyl)amino]-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5011.0 [1]
(2R)-3-(Pyrimidine-5-carbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC5063.0 [1]
(2R)-3-(Pyridine-4-carbonylamino)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propanoic acidIC50301.0 [1]
(2R)-2-[(2,3-Dichlorophenyl)sulfonylamino]-3-(thiophene-3-carbonylamino)propanoic acidIC5019.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[[4-[[[2-[2-[2-[2-[(2E)-2-[3-[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]propylidene]hydrazinyl]-2-oxoethoxy]ethoxy]ethoxy]acetyl]amino]methyl]phenyl]methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC5011000.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[4-[2-[(Z)-[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]oxyethylamino]-4-oxobutyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC505800.0 [1]
4-[[4-[(2S,5S,11S,14R)-14-Benzyl-11-(carboxymethyl)-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]phenyl]methylamino]-4-oxobutanoic acidIC5033700.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[[4-[[[4-[2-[(E)-[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]oxyethylamino]-4-oxobutanoyl]amino]methyl]phenyl]methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC50100000.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[[4-[[[2-[2-[2-[2-[2-[(E)-[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]oxyethylamino]-2-oxoethoxy]ethoxy]ethoxy]acetyl]amino]methyl]phenyl]methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC508300.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[[4-[[[2-[2-[2-[2-[(2E)-2-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylidene]hydrazinyl]-2-oxoethoxy]ethoxy]ethoxy]acetyl]amino]methyl]phenyl]methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC504800.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-8-[4-[[[2-[2-[2-(2-hydrazinyl-2-oxoethoxy)ethoxy]ethoxy]acetyl]amino]methyl]phenyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC5015600.0 [1]
2-[(2S,5R,8S,11S)-5-Benzyl-8-[4-[[[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetyl]amino]methyl]phenyl]-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acidIC5018800.0 [1]
Items per page: 1 - 10 of 58
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References

This online tool may be cited as follows

MLA

"Quest Database™ Vitronectin receptor alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/vitronectin-receptor-alpha-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Vitronectin receptor alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/vitronectin-receptor-alpha-inhibitors-ic50-ki.
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