Voltage-dependent L-type calcium channel alpha1C/alpha2delta/beta1b Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3,3-Diphenyl-1-[4-[phenyl-[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-one	IC50	6100.0 [1], 19600.0 [2]
	N,4-Dibenzhydrylpiperazine-1-carboxamide	IC50	1840.0 [1], 3500.0 [2]
	1-[4-[(3-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	6200.0 [1], 8500.0 [2]
	1-[4-[(R)-(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	4300.0 [1], 6900.0 [2]
	3,3-Diphenyl-1-[4-[phenyl-[3-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-one	IC50	1800.0 [1], 6600.0 [2]
	1-[4-(Diphenylmethyl)-1-piperazinyl]-3,3-diphenyl-1-propanone	IC50	12200.0 [1]
	2-(4-(Diphenylmethyl)piperazinyl)-N,N-diphenylethanamide	IC50	1600.0 [1]
	1-[4-[(2-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	106000.0 [1]
	1-[4-[(2,4-Dimethylphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	9600.0 [1]
	3,3-Diphenyl-1-[4-[phenyl-[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-one	IC50	10000.0 [1]
	3,3-Diphenyl-1-[4-[phenyl-(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl]propan-1-one	IC50	1400.0 [1]
	1-[4-[(4-Fluorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	1100.0 [1]
	1-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-3,3-diphenyl-propan-1-one	IC50	7400.0 [1]
	1-[4-[Bis(4-methoxyphenyl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	2900.0 [1]
	1-[4-[(4-Methylphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	2500.0 [1]
	1-[4-(1-Methyl-piperidin-4-ylmethyl)piperazin-1-yl]-3,3-diphenyl-propan-1-one	IC50	30000.0 [1]
	1-[4-[(4-Methoxyphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	1600.0 [1]
	2-[4-[(2,4-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	8600.0 [1]
	2-[4-[(2,4-Dimethylphenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	3800.0 [1]
	2-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	2900.0 [1]
	2-[4-[(3-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	1400.0 [1]
	2-[4-[(2,3-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	7900.0 [1]
	2-[4-[(2-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamide	IC50	1100.0 [1]
	N-Benzhydryl-4-[(2-chlorophenyl)-phenylmethyl]piperazine-1-carboxamide	IC50	610.0 [1]
	N-Benzhydryl-4-[(2,4-dichlorophenyl)-phenylmethyl]piperazine-1-carboxamide	IC50	1030.0 [1]
	N-Benzhydryl-4-[(3-chlorophenyl)-phenylmethyl]piperazine-1-carboxamide	IC50	17900.0 [1]
	1-[4-[(S)-(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	6800.0 [1]
	1-[4-[(1-Methylpiperidin-4-yl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	100000.0 [1]
	1-[4-[(1-Methylpiperidin-3-yl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	9300.0 [1]
	1-[4-[(4-Chlorophenyl)-(1-methylpiperidin-4-yl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	3100.0 [1]
	1-[4-[(4-Fluorophenyl)-(1-methylpiperidin-4-yl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	11000.0 [1]
	1-[4-[(3,5-Ditert-butyl-4-hydroxyphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	10000.0 [1]
	4-Benzhydryl-1-(3,3-diphenyl-propionyl)-piperazine-2-carboxylic acid ethyl ester	IC50	210000.0 [1]
	4-Benzhydryl-1-(3,3-diphenyl-propionyl)-piperazine-2-carboxylic acid	IC50	37140.0 [1]
	1-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-one;hydrochloride	IC50	133000.0 [1]
	1-[4-[(4-Methoxyphenyl)-[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-3,3-diphenylpropan-1-one	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 36 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Voltage-dependent L-type calcium channel alpha1C/alpha2delta/beta1b Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/voltage-dependent-l-type-calcium-channel-alpha1c-alpha2delta-beta1b-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Voltage-dependent L-type calcium channel alpha1C/alpha2delta/beta1b Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/voltage-dependent-l-type-calcium-channel-alpha1c-alpha2delta-beta1b-inhibitors-ic50-ki.
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