Name: 2-NBDG [2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose] *CAS#: 186689-07-6*
Brand: AAT Bioquest
SKU: 36702
Price: 174 USD
Availability: InStock

2-NBDG

2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; CAS#: 186689-07-6

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
36702	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of 2-NBDG [2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose] *CAS#: 186689-07-6* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	292.176 µL	1.461 mL	2.922 mL	14.609 mL	29.218 mL
5 mM	58.435 µL	292.176 µL	584.351 µL	2.922 mL	5.844 mL
10 mM	29.218 µL	146.088 µL	292.176 µL	1.461 mL	2.922 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	342.26 g/mol	=	mL	x	mM	=	mmol

Citations

View all 10 citations: Citation Explorer

CO2-dependent opening of Connexin 43 hemichannels

Authors:

Dospinsecu, Valentin Mihai and Mascarenhas, Alexander and Butler, Jack and Nijjar, Sarbjit and de Oliveira Taborda, Kyara and Connors, Sean and Huang, Lumei and Dale, Nicholas

Journal:

bioRxiv (2025): 2025--01

FGF21 alleviates adipose stem cell senescence via CD90 glycosylation-dependent glucose influx in remodeling healthy white adipose tissue

Authors:

Zhou, Zixin and Zhang, Huiying and Tao, Yan and Zang, Jinhao and Zhao, Jingyuan and Li, Huijie and Wang, Yalin and Wang, Tianci and Zhao, Hui and Wang, Fuwu and others,

Journal:

Redox Biology (2023): 102877

GLP-1RA Liraglutide and Semaglutide Improves Obesity-Induced Muscle Atrophy via SIRT1 Pathway

Authors:

Xiang, Jie and Qin, Liyan and Zhong, Jinling and Xia, Ning and Liang, Yuzhen

Journal:

Diabetes, Metabolic Syndrome and Obesity (2023): 2433--2446

Inhibition of human CD8+ T cells by the tumor metabolite methylthioadenosine: Mechanisms of action and putative strategies to improve antitumor activity

Authors:

Strobl, Carolin Dorothea

Metabolische und funktionelle Modulation von Effektor-T-Zellen durch humane doppelt-negative T-Zellen

Authors:

Haug, Tabea

References

View all 14 references: Citation Explorer

Transport of a Fluorescent Analogue of Glucose (2-NBDG) versus Radiolabeled Sugars by Rumen Bacteria and Escherichia coli

Authors:

Tao J, Diaz RK, Teixeira CR, Hackmann TJ.

Journal:

Biochemistry (2016): 2578

2-NBDG as a marker for detecting glucose uptake in reactive astrocytes exposed to oxygen-glucose deprivation in vitro

Authors:

Chen Y, Zhang J, Zhang XY.

Journal:

J Mol Neurosci (2015): 126

2-NBDG fluorescence imaging of hypermetabolic circulating tumor cells in mouse xenograft model of breast cancer

Authors:

Cai H, Peng F.

Journal:

J Fluoresc (2013): 213

Syzygium aqueum leaf extract and its bioactive compounds enhances pre-adipocyte differentiation and 2-NBDG uptake in 3T3-L1 cells

Authors:

Manaharan T, Ming CH, Palanisamy UD.

Journal:

Food Chem (2013): 354

In vivo imaging of epileptic activity using 2-NBDG, a fluorescent deoxyglucose analog

Authors:

Tsytsarev V, Maslov KI, Yao J, Parameswar AR, Demchenko AV, Wang LV.

Journal:

J Neurosci Methods (2012): 136

Physical properties

Molecular weight	342.26
Solvent	DMSO

Spectral properties

Excitation (nm)	467
Emission (nm)	538

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	186689-07-6

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Page updated on October 13, 2025