Name: 5(6)-TAMRA [5(6)-Carboxytetramethylrhodamine] *CAS 98181-63-6*
Brand: AAT Bioquest
SKU: 360
Availability: InStock

5(6)-TAMRA

5(6)-Carboxytetramethylrhodamine; CAS 98181-63-6

TAMRA is one of the most popular fluorophores used in various bioconjugations. TMR is a bright orange fluorophore. 5(6)-TAMRA is the mixture of two carboxy tetramethylrhodamine (TMR) isomers. It is used to modify amino and hydroxy groups using EDC-mediated couplings. It can be readily convert to the amine-reactive 5(6)-TAMRA, SE.

Protocol

COA

Catalog	Size	Price
360	100 mg	Price
361	1 g	Price
362	5 g	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of 5(6)-TAMRA [5(6)-Carboxytetramethylrhodamine] *CAS 98181-63-6* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	232.315 µL	1.162 mL	2.323 mL	11.616 mL	23.232 mL
5 mM	46.463 µL	232.315 µL	464.63 µL	2.323 mL	4.646 mL
10 mM	23.232 µL	116.158 µL	232.315 µL	1.162 mL	2.323 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	430.45 g/mol	=	mL	x	mM	=	mmol

Citations

View all 8 citations: Citation Explorer

Adjusting Heterodimeric Coiled-Coils (K/E Zipper) to Connect Autophagy-Inducing Peptide with Cell-Penetrating Peptide

Authors:

Hakata, Yoshiyuki and Yamashita, Kazuma and Hashimoto, Sonoko and Ohtsuki, Takashi and Miyazawa, Masaaki and Kitamatsu, Mizuki

Journal:

Pharmaceutics (2023): 1048

Complementary leucine zippering system for effective intracellular delivery of proteins by cell-penetrating peptides

Authors:

Kitamatsu, Mizuki and Yuasa, Hiroki and Ohtsuki, Takashi and Michiue, Hiroyuki

Journal:

Bioorganic \& Medicinal Chemistry (2021): 116036

Intracellular delivery of a peptide nucleic acid-based hybrid of an autophagy inducing peptide with a cell-penetrating peptide

Authors:

Hakata, Yoshiyuki and Ishikawa, Suzuka and Ohtsuki, Takashi and Miyazawa, Masaaki and Kitamatsu, Mizuki

Journal:

Organic \& Biomolecular Chemistry (2020): 1978--1986

CCR2 signal facilitates thymic egress by priming thymocyte responses to sphingosine-1-phosphate

Authors:

Aili, Abudureyimujiang and Zhang, Jie and Wu, Jia and Wu, Haoming and Sun, Xiuyuan and He, Qihua and Jin, Rong and Zhang, Yu

Journal:

Frontiers in immunology (2018): 1263

Amikacin liposome inhalation suspension (ALIS) penetrates non-tuberculous mycobacterial biofilms and enhances amikacin uptake into macrophages

Authors:

Zhang, Jimin and Leifer, Franziska and Rose, Sasha and Chun, Dung Yu and Thaisz, Jill and Herr, Tracey and Nashed, Mary and Joseph, Jayanthi and Perkins, Walter R and DiPetrillo, Keith

Journal:

Frontiers in microbiology (2018)

References

View all 96 references: Citation Explorer

A fluorescence polarization assay for screening inhibitors against the ribonuclease H activity of HIV-1 reverse transcriptase

Authors:

Nakayama GR, Bingham P, Tan D, Maegley KA.

Journal:

Anal Biochem (2006): 260

G Quadruplex-Based FRET Probes with the Thrombin-Binding Aptamer (TBA) Sequence Designed for the Efficient Fluorometric Detection of the Potassium Ion

Authors:

Nagatoishi S, Nojima T, Galezowska E, Juskowiak B, Takenaka S.

Journal:

Chembiochem (2006): 1730

A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway

Authors:

Fischer R, Bachle D, Fotin-Mleczek M, Jung G, Kalbacher H, Brock R.

Journal:

Chembiochem (2006): 1428

Electrostatic-gated transport in chemically modified glass nanopore electrodes

Authors:

Wang G, Zhang B, Wayment JR, Harris JM, White HS.

Journal:

J Am Chem Soc (2006): 7679

Fluorescence anisotropy and FRET studies of G-quadruplex formation in presence of different cations

Authors:

Juskowiak B, Galezowska E, Zawadzka A, Gluszynska A, Takenaka S.

Journal:

Spectrochim Acta A Mol Biomol Spectrosc (2006): 835

Physical properties

Molecular weight	430.45
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.32
Correction factor (280 nm)	0.178
Extinction coefficient (cm ^-1 M ^-1)	90000
Excitation (nm)	552
Emission (nm)	578

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	98181-63-6

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Page updated on October 13, 2025