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5(6)-TAMRA C6 maleimide

Chemical structure for 5(6)-TAMRA C6 maleimide
Chemical structure for 5(6)-TAMRA C6 maleimide
Ordering information
Price ()
Catalog Number423
Unit Size
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Additional ordering information
InternationalSee distributors
ShippingStandard overnight for United States, inquire for international
Physical properties
Molecular weight623.65
Spectral properties
Correction Factor (260 nm)0.32
Correction Factor (280 nm)0.178
Extinction coefficient (cm -1 M -1)90000
Excitation (nm)552
Emission (nm)578
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure


Molecular weight
Correction Factor (260 nm)
Correction Factor (280 nm)
Extinction coefficient (cm -1 M -1)
Excitation (nm)
Emission (nm)
5(6)-TAMRA C6 maleimide is an excellent replacement for tetramethylrhodamine-5-(and 6)-maleimide. It selectively reacts with thiol groups of peptides, proteins and other biological molecules (such as thiol-modified oligonucleotides and small thiol-containing organic molecules). It might give higher conjugation yield than tetramethylrhodamine-5-(and 6)-maleimide under similar conjugation conditions. 5(6)-TMR C6 maleimide has the spectral properties identical to those of tetramethylrhodamine-5-(and 6)-maleimide, thus all the instrument settings of the tetramethylrhodamine-5-(and 6)-maleimide would be applicable to the applications of 5-TMR C6 maleimide conjugates.


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of 5(6)-TAMRA C6 maleimide to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM160.346 µL801.732 µL1.603 mL8.017 mL16.035 mL
5 mM32.069 µL160.346 µL320.693 µL1.603 mL3.207 mL
10 mM16.035 µL80.173 µL160.346 µL801.732 µL1.603 mL

Molarity calculator

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Spectral properties

Correction Factor (260 nm)0.32
Correction Factor (280 nm)0.178
Extinction coefficient (cm -1 M -1)90000
Excitation (nm)552
Emission (nm)578


View all 1 citations: Citation Explorer
Detection and destruction of HER2-positive cancer cells by Ultra Quenchbody-siRNA complex
Authors: Dong, Jinhua and Oka, Yuya and Jeong, Hee-Jin and Ohmuro-Matsuyama, Yuki and Ueda, Hiroshi
Journal: Biotechnology and Bioengineering (2020): 1259--1269


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Fluorometric measurements of intermolecular distances between the alpha and beta subunits of the Na+/K+-ATPase
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