Name: 6-dROX [6-Carboxy-4,7-dichloror-X-hodamine]
Brand: AAT Bioquest
SKU: 311
Price: 4627 USD
Availability: InStock

6-dROX

6-Carboxy-4,7-dichloror-X-hodamine

6-dROX (6-Carboxy-4,7-dichloror-X-hodamine) is one of the four critical 4,7-dichloro-rhodamine dyes used as the BigDye terminators for DNA sequencing in combination with dR110, dR6G and dROX. ABI PRISM® BigDye™ Terminator Cycle Sequencing is the classic method for DNA sequencing.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
311	25 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of 6-dROX [6-Carboxy-4,7-dichloror-X-hodamine] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	141.906 µL	709.532 µL	1.419 mL	7.095 mL	14.191 mL
5 mM	28.381 µL	141.906 µL	283.813 µL	1.419 mL	2.838 mL
10 mM	14.191 µL	70.953 µL	141.906 µL	709.532 µL	1.419 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	704.69 g/mol	=	mL	x	mM	=	mmol

References

View all 6 references: Citation Explorer

Design and synthesis of fluorescence-labeled nucleotide with a cleavable azo linker for DNA sequencing

Authors:

Tan, L.; Liu, Y.; Yang, Q.; Li, X.; Wu, X. Y.; Gong, B.; Shen, Y. M.; Shao, Z.

Journal:

Chem Commun (Camb) (2016): 954-7

Synthesis of novel tyrosinyl FRET cassettes, terminators, and their potential use in DNA sequencing

Authors:

Sudhakar Rao, T.; Zhang, W.; Xiao, H.; Flick, P.; Kumar, S.; Nampalli, S.

Journal:

Nucleosides Nucleotides Nucleic Acids (2003): 1443-5

Design strategies and performance of custom DNA sequencing primers

Authors:

Buck, G. A.; Fox, J. W.; Gunthorpe, M.; Hager, K. M.; Naeve, C. W.; Pon, R. T.; Adams, P. S.; Rush, J.

Journal:

Biotechniques (1999): 528-36

Improved DNA sequencing accuracy and detection of heterozygous alleles using manganese citrate and different fluorescent dye terminators

Authors:

Korch, C.; Drabkin, H.

Journal:

Genome Res (1999): 588-95

Peak height pattern in dichloro-rhodamine and energy transfer dye terminator sequencing

Authors:

Zakeri, H.; Amparo, G.; Chen, S. M.; Spurgeon, S.; Kwok, P. Y.

Journal:

Biotechniques (1998): 406-10, 412-4

Physical properties

Molecular weight	704.69
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on October 30, 2025