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Ac-DEVD-CHO *CAS 169332-60-9*
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Application notes
Ac-DEVD-CHO is a reversible inhibitor of IL-1? converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).
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Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of Ac-DEVD-CHO *CAS 169332-60-9* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 199.017 µL | 995.084 µL | 1.99 mL | 9.951 mL | 19.902 mL |
| 5 mM | 39.803 µL | 199.017 µL | 398.034 µL | 1.99 mL | 3.98 mL |
| 10 mM | 19.902 µL | 99.508 µL | 199.017 µL | 995.084 µL | 1.99 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
| Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
| / | = | x | = |
Product family
| Name | Excitation (nm) | Emission (nm) |
| Ac-DEVD-AFC *CAS 201608-14-2* | 376 | 482 |
| Ac-DEVD-AMC *CAS 169332-61-0* | 341 | 441 |
| Ac-DEVD-aminoluciferin | 362 | 499 |
Citations
View all 3 citations: Citation Explorer
Ferrous-Supply-Regeneration Nanoengineering for Cancer Cell Specific Ferroptosis in Combination with Imaging-Guided Photodynamic Therapy
Authors: Liu, Tao and Liu, Wenlong and Zhang, Mingkang and Yu, Wuyang and Gao, Fan and Li, Chuxin and Wang, Shi-Bo and Feng, Jun and Zhang, Xian-Zheng
Journal: ACS nano (2018)
Authors: Liu, Tao and Liu, Wenlong and Zhang, Mingkang and Yu, Wuyang and Gao, Fan and Li, Chuxin and Wang, Shi-Bo and Feng, Jun and Zhang, Xian-Zheng
Journal: ACS nano (2018)
pH-Assisted surface functionalization of selenium nanoparticles with curcumin to achieve enhanced cancer chemopreventive activity
Authors: Yu, Shaoxuan and Wang, Yanru and Zhang, Wentao and Zhang, Yuhuan and Zhu, Wenxin and Liu, Yingnan and Zhang, Daohong and Wang, Jianlong
Journal: RSC Advances (2016): 72213--72223
Authors: Yu, Shaoxuan and Wang, Yanru and Zhang, Wentao and Zhang, Yuhuan and Zhu, Wenxin and Liu, Yingnan and Zhang, Daohong and Wang, Jianlong
Journal: RSC Advances (2016): 72213--72223
Synthesis and evaluation of N-acyl-substituted 1, 2-benzisothiazol-3-one derivatives as caspase-3 inhibitors
Authors: Li, Zhenghui and Pan, Yang and Zhong, Weilong and Zhu, Yunpeng and Zhao, Yongle and Li, Lixin and Liu, Wei and Zhou, Honggang and Yang, Cheng
Journal: Bioorganic \& Medicinal Chemistry (2014): 6735--6745
Authors: Li, Zhenghui and Pan, Yang and Zhong, Weilong and Zhu, Yunpeng and Zhao, Yongle and Li, Lixin and Liu, Wei and Zhou, Honggang and Yang, Cheng
Journal: Bioorganic \& Medicinal Chemistry (2014): 6735--6745
References
View all 67 references: Citation Explorer
In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation
Authors: Lerma-Diaz JM, Hern and ez-Flores G, Dominguez-Rodriguez JR, Ortiz-Lazareno PC, Gomez-Contreras P, Cervantes-Munguia R, Scott-Algara D, Aguilar-Lemarroy A, Jave-Suarez LF, Bravo-Cuellar A.
Journal: Immunol Lett (2006): 149
Authors: Lerma-Diaz JM, Hern and ez-Flores G, Dominguez-Rodriguez JR, Ortiz-Lazareno PC, Gomez-Contreras P, Cervantes-Munguia R, Scott-Algara D, Aguilar-Lemarroy A, Jave-Suarez LF, Bravo-Cuellar A.
Journal: Immunol Lett (2006): 149
Measurement of two caspase activities simultaneously in living cells by a novel dual FRET fluorescent indicator probe
Authors: Wu X, Simone J, Hewgill D, Siegel R, Lipsky PE, He L.
Journal: Cytometry A (2006): 477
Authors: Wu X, Simone J, Hewgill D, Siegel R, Lipsky PE, He L.
Journal: Cytometry A (2006): 477
Quantitative measurement of caspase-3 activity in a living starfish egg
Authors: Sakaue M, Motoyama Y, Yamamoto K, Shiba T, Teshima T, Chiba K.
Journal: Biochem Biophys Res Commun (2006): 878
Authors: Sakaue M, Motoyama Y, Yamamoto K, Shiba T, Teshima T, Chiba K.
Journal: Biochem Biophys Res Commun (2006): 878
Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3
Authors: Miller TJ, Schneider RJ, Miller JA, Martin BP, Al-Ubaidi MR, Agarwal N, Dethloff LA, Philbert MA.
Journal: Neurotoxicology (2006): 44
Authors: Miller TJ, Schneider RJ, Miller JA, Martin BP, Al-Ubaidi MR, Agarwal N, Dethloff LA, Philbert MA.
Journal: Neurotoxicology (2006): 44
Diallyl Trisulfide Induces Apoptosis of Human Gastric Cancer Cell Line MGC803 Through Caspase-3 Pathway.
Authors: Xiao XL, Peng J, Su Q, Xiang SL, Tang GH, Huang YS, Zhou XT.
Journal: Ai Zheng (2006): 1247
Authors: Xiao XL, Peng J, Su Q, Xiang SL, Tang GH, Huang YS, Zhou XT.
Journal: Ai Zheng (2006): 1247