Name: Ac-DEVD-CHO *CAS 169332-60-9*
Brand: AAT Bioquest
SKU: 13403
Price: 115 USD
Availability: InStock

Ac-DEVD-CHO

CAS 169332-60-9

Ac-DEVD-CHO is a reversible inhibitor of IL-1? converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).

Protocol

SDS

COA

Catalog	Size	Price	Quantity
13403	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Ac-DEVD-CHO *CAS 169332-60-9* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	199.017 µL	995.084 µL	1.99 mL	9.951 mL	19.902 mL
5 mM	39.803 µL	199.017 µL	398.034 µL	1.99 mL	3.98 mL
10 mM	19.902 µL	99.508 µL	199.017 µL	995.084 µL	1.99 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	502.47 g/mol	=	mL	x	mM	=	mmol

Citations

View all 3 citations: Citation Explorer

Ferrous-Supply-Regeneration Nanoengineering for Cancer Cell Specific Ferroptosis in Combination with Imaging-Guided Photodynamic Therapy

Authors:

Liu, Tao and Liu, Wenlong and Zhang, Mingkang and Yu, Wuyang and Gao, Fan and Li, Chuxin and Wang, Shi-Bo and Feng, Jun and Zhang, Xian-Zheng

Journal:

ACS nano (2018)

pH-Assisted surface functionalization of selenium nanoparticles with curcumin to achieve enhanced cancer chemopreventive activity

Authors:

Yu, Shaoxuan and Wang, Yanru and Zhang, Wentao and Zhang, Yuhuan and Zhu, Wenxin and Liu, Yingnan and Zhang, Daohong and Wang, Jianlong

Journal:

RSC Advances (2016): 72213--72223

Synthesis and evaluation of N-acyl-substituted 1, 2-benzisothiazol-3-one derivatives as caspase-3 inhibitors

Authors:

Li, Zhenghui and Pan, Yang and Zhong, Weilong and Zhu, Yunpeng and Zhao, Yongle and Li, Lixin and Liu, Wei and Zhou, Honggang and Yang, Cheng

Journal:

Bioorganic \& Medicinal Chemistry (2014): 6735--6745

References

View all 67 references: Citation Explorer

In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation

Authors:

Lerma-Diaz JM, Hern and ez-Flores G, Dominguez-Rodriguez JR, Ortiz-Lazareno PC, Gomez-Contreras P, Cervantes-Munguia R, Scott-Algara D, Aguilar-Lemarroy A, Jave-Suarez LF, Bravo-Cuellar A.

Journal:

Immunol Lett (2006): 149

Measurement of two caspase activities simultaneously in living cells by a novel dual FRET fluorescent indicator probe

Authors:

Wu X, Simone J, Hewgill D, Siegel R, Lipsky PE, He L.

Journal:

Cytometry A (2006): 477

Quantitative measurement of caspase-3 activity in a living starfish egg

Authors:

Sakaue M, Motoyama Y, Yamamoto K, Shiba T, Teshima T, Chiba K.

Journal:

Biochem Biophys Res Commun (2006): 878

Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3

Authors:

Miller TJ, Schneider RJ, Miller JA, Martin BP, Al-Ubaidi MR, Agarwal N, Dethloff LA, Philbert MA.

Journal:

Neurotoxicology (2006): 44

Diallyl Trisulfide Induces Apoptosis of Human Gastric Cancer Cell Line MGC803 Through Caspase-3 Pathway.

Authors:

Xiao XL, Peng J, Su Q, Xiang SL, Tang GH, Huang YS, Zhou XT.

Journal:

Ai Zheng (2006): 1247

Physical properties

Molecular weight	502.47
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	169332-60-9

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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