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Ac-IETD-AFC
CAS 211990-57-7
Ac-IETD-AFC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. This substrate is hydrlyzed by caspase 8 to generate highly fluorescent 7-amido-4-trifluoromethylcoumarin (AFC).
Chemical structure for Ac-IETD-AFC *CAS 211990-57-7*
Chemical structure for Ac-IETD-AFC *CAS 211990-57-7*
CatalogSize
Price
Quantity
134105 mg
Price
 
Physical properties

Molecular weight729.65
SolventDMSO
Spectral properties

Extinction coefficient (cm -1 M -1)
17000
1
Excitation (nm)376
Emission (nm)482
Quantum yield
0.53
1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
CAS211990-57-7
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Page updated on October 12, 2025