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Acridinium Amine
Acridinium is a univalent radical derived from acridine. Acridinium amines are synthetic molecules known for their strong chemiluminescence, commonly used to label molecules containing carbonyl groups, such as aldehydes or carboxyl groups. The chemiluminescence of acridinium amines is triggered by exposure to an alkaline hydrogen peroxide solution, facilitating their use in sensitive detection methodologies within immunoassays and various biological assays. For accurate signal detection in a chemiluminescence analyzer, a trigger solution containing (A) 0.1% H₂O₂ and 0.1 M HNO₃, and (B) 0.25 M NaOH and 2% Triton X-100 is recommended.
References
View all 50 references: Citation Explorer
Self-Assembled Bis-Acridinium Tweezer Equilibria Controlled by Multi-Responsive Properties.
Authors: Hu, Johnny and Launay, Jean-Pierre and Chaumont, Alain and Heitz, Valérie and Jacquot de Rouville, Henri-Pierre
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2024): e202401866
Authors: Hu, Johnny and Launay, Jean-Pierre and Chaumont, Alain and Heitz, Valérie and Jacquot de Rouville, Henri-Pierre
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2024): e202401866
Cytotoxicity of acridinium-based ionic liquids: Structure-activity relationship and mechanistic studies.
Authors: Roy, Ritik and Chick, Phoenix and York, Edward and Rawling, Tristan
Journal: Chemico-biological interactions (2024): 111042
Authors: Roy, Ritik and Chick, Phoenix and York, Edward and Rawling, Tristan
Journal: Chemico-biological interactions (2024): 111042
Acridinium-Based Chemiluminescent Receptor-Ligand Binding Assay for Protein/Peptide Hormones.
Authors: Daubermann, André Guilherme and Dressano, Keini and de Oliveira Ceciliato, Paulo Henrique and Moura, Daniel S
Journal: Methods in molecular biology (Clifton, N.J.) (2024): 253-263
Authors: Daubermann, André Guilherme and Dressano, Keini and de Oliveira Ceciliato, Paulo Henrique and Moura, Daniel S
Journal: Methods in molecular biology (Clifton, N.J.) (2024): 253-263
Zwitterionic Acridinium Amidate: A Nitrogen-Centered Radical Catalyst for Photoinduced Direct Hydrogen Atom Transfer.
Authors: Entgelmeier, Lukas-Maximilian and Mori, Soichiro and Sendo, Shion and Yamaguchi, Rie and Suzuki, Ryuhei and Yanai, Takeshi and Mancheño, Olga García and Ohmatsu, Kohsuke and Ooi, Takashi
Journal: Angewandte Chemie (International ed. in English) (2024): e202404890
Authors: Entgelmeier, Lukas-Maximilian and Mori, Soichiro and Sendo, Shion and Yamaguchi, Rie and Suzuki, Ryuhei and Yanai, Takeshi and Mancheño, Olga García and Ohmatsu, Kohsuke and Ooi, Takashi
Journal: Angewandte Chemie (International ed. in English) (2024): e202404890
Crystal structure, intermolecular interactions, charge-density distribution and ADME properties of the acridinium 4-nitrobenzoate and 2-amino-3-methylpyridinium 4-nitrobenzoate salts: a combined experimental and theoretical study.
Authors: Balasubramanian, Hemalatha and Mariappan, Petchi Raman and Poomani, Kumaradhas
Journal: Acta crystallographica. Section C, Structural chemistry (2024): 115-122
Authors: Balasubramanian, Hemalatha and Mariappan, Petchi Raman and Poomani, Kumaradhas
Journal: Acta crystallographica. Section C, Structural chemistry (2024): 115-122
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