Calculator
Acridinium Maleimide
Acridinium is a univalent radical derived from acridine. Acridinium maleimides are synthetic molecules known for their strong chemiluminescence, commonly used for labeling thiol groups on proteins, oligonucleotide thiophosphates, or low molecular weight ligands. The chemiluminescence of acridinium maleimides is triggered by exposure to an alkaline hydrogen peroxide solution, facilitating their use in sensitive detection methodologies within immunoassays and various biological assays. For accurate signal detection in a chemiluminescence analyzer, a trigger solution containing (A) 0.1% H₂O₂ and 0.1 M HNO₃, and (B) 0.25 M NaOH and 2% Triton X-100 is recommended.
References
View all 50 references: Citation Explorer
Development of a rapid and ultrasensitive magnetic chemiluminescence immunoassay for the detection of adiponectin and its clinical application.
Authors: Li, Jiexia and Fan, Zhuqiao and Chen, Hanqi and Maria Da Costa, Ernestina and Zhou, Xiaomian and Yu, Nan
Journal: Journal of pharmaceutical and biomedical analysis (2024): 115961
Authors: Li, Jiexia and Fan, Zhuqiao and Chen, Hanqi and Maria Da Costa, Ernestina and Zhou, Xiaomian and Yu, Nan
Journal: Journal of pharmaceutical and biomedical analysis (2024): 115961
Elevated Serum Neurofilament Light Chain Levels Are Associated With All-Cause Mortality: Evidence From National Health and Nutrition Examination Survey.
Authors: Chen, Xiaotong and Lin, Yong and Wei, Kai
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences (2023): 2382-2386
Authors: Chen, Xiaotong and Lin, Yong and Wei, Kai
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences (2023): 2382-2386
Syntheses of Hindered-Polymethylacridinium Esters with Potential for Biological Probe Nanoarchitectonics.
Authors: Smith, Keith and Ahmed, Zabair and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Journal of oleo science (2023): 447-460
Authors: Smith, Keith and Ahmed, Zabair and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Journal of oleo science (2023): 447-460
Synthesis, structure elucidation, and chemiluminescent activity of new 9-substituted 10-(ω-(succinimidyloxycarbonyl)alkyl)acridinium esters.
Authors: Smith, Keith and Mu, Xiaojing and Li, Zhaoqiang and Holland, Andy M and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Luminescence : the journal of biological and chemical luminescence (2023): 487-496
Authors: Smith, Keith and Mu, Xiaojing and Li, Zhaoqiang and Holland, Andy M and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Luminescence : the journal of biological and chemical luminescence (2023): 487-496
Synthesis and chemiluminescent characteristics of two new acridinium esters.
Authors: Smith, Keith and Mu, Xiaojing and Li, Zhaoqiang and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Luminescence : the journal of biological and chemical luminescence (2023): 1857-1863
Authors: Smith, Keith and Mu, Xiaojing and Li, Zhaoqiang and Woodhead, J Stuart and El-Hiti, Gamal A
Journal: Luminescence : the journal of biological and chemical luminescence (2023): 1857-1863
Page updated on May 19, 2025
Safety data sheet