Ala-R110

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Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
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Physical properties

Molecular weight	545.42
Solvent	DMSO

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	80000
Excitation (nm)	500
Emission (nm)	522

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Ala-R110 to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	183.345 µL	916.725 µL	1.833 mL	9.167 mL	18.334 mL
5 mM	36.669 µL	183.345 µL	366.69 µL	1.833 mL	3.667 mL
10 mM	18.334 µL	91.672 µL	183.345 µL	916.725 µL	1.833 mL

Molarity calculator

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Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	80000
Excitation (nm)	500
Emission (nm)	522

Product Family

Name	Excitation (nm)	Emission (nm)
Ala-AMC	341	441

Images

Figure 1. Chemical structure for Ala-R110.

References

View all 50 references: Citation Explorer

Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells.
Authors: Yamaya, Mutsuo and Nishimura, Hidekazu and Deng, Xue and Sugawara, Mitsuru and Watanabe, Oshi and Nomura, Kazuhiro and Shimotai, Yoshitaka and Momma, Haruki and Ichinose, Masakazu and Kawase, Tetsuaki
Journal: Respiratory investigation (2020): 155-168

Fluorogenic l-alanylaminopeptidase substrates derived from 6-amino-2-hetarylquinolines and 7-amino-3-hetarylcoumarins and their potential applications in diagnostic microbiology.
Authors: Cellier-Rastit, Marie and James, Arthur L and Orenga, Sylvain and Perry, John D and Robinson, Shaun N and Turnbull, Graeme and Stanforth, Stephen P
Journal: Bioorganic & medicinal chemistry letters (2019): 1227-1231

A Selective, Dual Emission β-Alanine Aminopeptidase Activated Fluorescent Probe for the Detection of Pseudomonas aeruginosa, Burkholderia cepacia, and Serratia marcescens.
Authors: Váradi, Linda and Najib, Elias Y and Hibbs, David E and Perry, John D and Groundwater, Paul W
Journal: Molecules (Basel, Switzerland) (2019)

In situ imaging of aminopeptidase N activity in hepatocellular carcinoma: a migration model for tumour using an activatable two-photon NIR fluorescent probe.
Authors: Li, Haidong and Li, Yueqing and Yao, Qichao and Fan, Jiangli and Sun, Wen and Long, Saran and Shao, Kun and Du, Jianjun and Wang, Jingyun and Peng, Xiaojun
Journal: Chemical science (2019): 1619-1625

CD7 is expressed on a subset of normal CD34-positive myeloid precursors.
Authors: Kriegsmann, Katharina and Löffler, Harald and Eckstein, Volker and Schulz, Renate and Kräker, Sandra and Braun, Ute and Luft, Thomas and Hegenbart, Ute and Schönland, Stefan and Dreger, Peter and Krämer, Alwin and Ho, Anthony D and Müller-Tidow, Carsten and Hundemer, Michael
Journal: European journal of haematology (2018): 318-325

Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
Authors: Wang, Xiaoqing and Liu, Yang and Liu, Wei and Zhang, Yongfei and Guo, Feng and Zhang, Lijuan and Cui, Mingyu and Liu, Shuai and Wu, Rongde
Journal: Molecular medicine reports (2018): 4531-4539

FACS isolation of endothelial cells and pericytes from mouse brain microregions.
Authors: Crouch, Elizabeth E and Doetsch, Fiona
Journal: Nature protocols (2018): 738-751

Aminopeptidase N (CD13) targeted MR and NIRF dual-modal imaging of ovarian tumor xenograft.
Authors: Meng, Ying and Zhang, Zixin and Liu, Kang and Ye, Ling and Liang, Yuting and Gu, Wei
Journal: Materials science & engineering. C, Materials for biological applications (2018): 968-974

A latent green fluorescent styrylcoumarin probe for the selective growth and detection of Gram negative bacteria.
Authors: Váradi, Linda and Wang, Miaoyi and Mamidi, Ramesh R and Luo, Jia Lin and Perry, John D and Hibbs, David E and Groundwater, Paul W
Journal: Bioorganic & medicinal chemistry (2018): 4745-4750

Ultrasensitive Detection of Aminopeptidase N Activity in Urine and Cells with a Ratiometric Fluorescence Probe.
Authors: He, Xinyuan and Xu, Yanhui and Shi, Wen and Ma, Huimin
Journal: Analytical chemistry (2017): 3217-3221