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AMC [7-Amino-4-methylcoumarin] *CAS 26093-31-2*

This compound is the precursor for a variety of AMC enzyme substrates. It is also used as a calibration standard for AMC-based enzyme substrates. Fluorogenic AMC substrates are widely used for measuring a variety of protease activities.

Spectrum

Citations

View all 3 citations: Citation Explorer
MXene-sensitized electrochemiluminescence sensor for thrombin activity detection and inhibitor screening
Authors: Deng, Zijie and Tan, Xueping and Guo, Dongnan and Zhang, Jing and Xu, Dan and Hou, Xiaofang and Wang, Sicen and Zhang, Junbo and Wei, Fen and Zhang, Dongdong
Journal: Microchimica Acta (2023): 328
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice
Authors: Xiao, Fei and Jiang, Haizhou and Li, Zi and Jiang, Xiaoxue and Chen, Shanghai and Niu, Yuguo and Yin, Hanrui and Shu, Yousheng and Peng, Bo and Lu, Wei and others,
Journal: Nature Communications (2023): 2523
Modulation of CD4+ T-cell activation by CD95 co-stimulation
Authors: Paulsen, Maren and Valentin, Signe and Mathew, Biny and Adam-Klages, Sabine and Bertsch, Uwe and Lavrik, Inna and Krammer, Peter H and Kabelitz, Dieter and Janssen, Ottmar
Journal: Cell Death & Differentiation (2011): 619--631

References

View all 142 references: Citation Explorer
Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease
Authors: Bl, undefined and ini F, Sinforiani E, Pacchetti C, Samuele A, Bazzini E, Zangaglia R, Nappi G, Martignoni E.
Journal: Neurology (2006): 529
Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids
Authors: Serveau-Avesque C, Martino MF, Herve-Grepinet V, Hazouard E, Gauthier F, Diot E, Lalmanach G.
Journal: Biol Cell (2006): 15
A role for Angiotensin-converting enzyme in the characterization, enrichment, and proliferation potential of adult murine pituitary colony-forming cells
Authors: Lepore DA, Jokubaitis VJ, Simmons PJ, Roeszler KN, Rossi R, Bauer K, Thomas PQ.
Journal: Stem Cells (2006): 2382
Paenidase, a Novel D-Aspartyl Endopeptidase from Paenibacillus sp. B38: Purification and Substrate Specificity
Authors: Takahashi S, Ogasawara H, Hiwatashi K, Hori K, Hata K, Tachibana T, Itoh Y, Sugiyama T.
Journal: J Biochem (Tokyo) (2006): 197
Recovery of free oligosaccharides from derivatives labeled by reductive amination
Authors: Suzuki S, Fujimori T, Yodoshi M.
Journal: Anal Biochem (2006): 94
Page updated on December 13, 2024

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Catalog Number
515253
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Physical properties

Molecular weight

175.19

Solvent

DMSO

Spectral properties

Excitation (nm)

341

Emission (nm)

441

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501

CAS

26093-31-2
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