Amplite® Colorimetric Gama-Glutamyltransferase (GGT) Activity Assay Kit

The Amplite® Colorimetric Gamma-Glutamyltransferase (GGT) Activity Assay Kit provides an efficient and straightforward method for measuring GGT activity across various sample types. This assay utilizes a coupled enzyme reaction in which GGT catalyzes the conversion of a substrate into a colored product detectable at 418 nm, directly reflecting the GGT concentration in the sample. It is compatible with a wide range of biological samples, including cells, tissue extracts, and serum, and is suitable for high-throughput systems. γ-Glutamyltransferase (also known as GGT) is a mammalian enzyme playing an important role in the anti-oxidant defense mechanism of cells. It is located in cell membranes and is known for facilitating the transfer of γ-glutamyl moieties between molecules during glutathione regulation and xenobiotic detoxification. Elevated levels of serum GGT are linked to cardiovascular and liver diseases, metabolic syndrome, and oxidative stress. Consequently, GGT is a valuable biomarker for liver dysfunction and disorders related to oxidative stress.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
11801	100 Tests	Price

References

View all 50 references: Citation Explorer

Safety evaluation of the food enzyme protein-glutamine γ-glutamyltransferase from the non-genetically modified Streptomyces mobaraensis strain M2020197.

Authors:

, and Lambré, Claude and Barat Baviera, José Manuel and Bolognesi, Claudia and Cocconcelli, Pier Sandro and Crebelli, Riccardo and Gott, David Michael and Grob, Konrad and Lampi, Evgenia and Mengelers, Marcel and Mortensen, Alicja and Rivière, Gilles and Steffensen, Inger-Lise and Tlustos, Christina and Van Loveren, Henk and Vernis, Laurence and Zorn, Holger and Herman, Lieve and Roos, Yrjö and Aguilera, Jaime and Andryszkiewicz, Magdalena and Cavanna, Daniele and Kovalkovicova, Natalia and Liu, Yi and di Piazza, Giulio and Chesson, Andrew

Journal:

EFSA journal. European Food Safety Authority (2024): e8509

Does gamma-glutamyltransferase correlate with liver tumor burden in neuroendocrine tumors?

Authors:

Schmidt, Benjamin Christopher and Leiderer, Miriam Theresa and Amin, Tania and Viol, Fabrice and Huber, Samuel and Henes, Frank Oliver and Schrader, Jörg

Journal:

Endocrine (2024): 511-518

The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient.

Authors:

Virgolici, Bogdana and Dobre, Maria Zinaida and Lixandru, Daniela and Petcu, Laura and Picu, Ariana and Ionescu-Târgovişte, Constantin and Greabu, Maria and Bacanu, Elena Violeta

Journal:

Romanian journal of internal medicine = Revue roumaine de medecine interne (2024): 203-209

Changes in serum uric acid, serum uric acid/serum creatinine ratio, and gamma-glutamyltransferase might predict the efficacy of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.

Authors:

Shao, Zhenyong and Xu, Yuyan and Zhang, Xuebang and Zou, Changlin and Xie, Raoying

Journal:

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2024): 523-534

Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activity.

Authors:

Harrer, Philip and Inderhees, Julica and Zhao, Chen and Schormair, Barbara and Tilch, Erik and Gieger, Christian and Peters, Annette and Jöhren, Olaf and Fleming, Thomas and Nawroth, Peter P and Berger, Klaus and Hermesdorf, Marco and Winkelmann, Juliane and Schwaninger, Markus and Oexle, Konrad

Journal:

EBioMedicine (2024): 105007

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
UNSPSC	12352200

Instrument settings

Absorbance microplate reader
Absorbance	418 nm
Recommended plate	Clear bottom

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on December 11, 2025

Component A: GGT Assay Buffer	1 Bottle (25 mL)
Component B: GGT Substrate	1 Vial
Component C: GGT Positive Control	1 Vial (50 µg)
Component D: pNA Standard	1 Vial (0.4 mL)