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AAT Bioquest

BAPTA, AM *UltraPure Grade* *CAS 126150-97-8*

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Physical properties
Molecular weight764.68
SolventDMSO
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
Alternative formats
BAPTA, AM *CAS 126150-97-8*

OverviewpdfSDSpdfProtocol


CAS
126150-97-8
Molecular weight
764.68
BAPTA AM is cell-permeable version of BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), a cell-permeable calcium chelator. This BAPTA derivative is used for adjusting calcium concentrations in cells and tissues. BAPTA is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of BAPTA, AM *UltraPure Grade* *CAS 126150-97-8* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM130.774 µL653.868 µL1.308 mL6.539 mL13.077 mL
5 mM26.155 µL130.774 µL261.547 µL1.308 mL2.615 mL
10 mM13.077 µL65.387 µL130.774 µL653.868 µL1.308 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Citations


View all 8 citations: Citation Explorer
Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels
Authors: Yang, Xinhui and Jiang, Jiangtao and Yang, Xinyan and Han, Jichun and Zheng, Qiusheng
Journal: Molecular medicine reports (2016): 911--919
Helicobacter pylori induces IL-1&beta; protein through the inflammasome activation in differentiated macrophagic cells
Authors: Kameoka, Shoichiro and Kameyama, Takeshi and Hayashi, Takaya and Sato, Seiichi and Ohnishi, Naomi and Hayashi, Takeru and Murata-Kamiya, Naoko and Higashi, Hideaki and Hatakeyama, Masanori and Takaoka, Akinori
Journal: Biomedical Research (2016): 21--27
Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload
Authors: Xiao, Juan and Feng, Xueping and Huang, Xiao-Ying and Huang, Zhongshi and Huang, Yanqiang and Li, Chaogan and Li, Genliang and Nong, Song and Wu, Ruoshi and Huang, Yongzhi and others, undefined
Journal: Molecular Medicine (2016): 643
Ras guanyl nucleotide releasing protein 2 affects cell viability and cell--matrix adhesion in ECV304 endothelial cells
Authors: Takino, Junichi and Nagamine, Kentaro and Hori, Takamitsu
Journal: Cell adhesion &amp; migration (2013): 262--266
Delayed administration of the nucleic acid analog 2Cl-C. OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke
Authors: Okabe, Naohiko and Nakamura, Emi and Himi, Naoyuki and Narita, Kazuhiko and Tsukamoto, Ikuko and Maruyama, Tokumi and Sakakibara, Norikazu and Nakamura, Takehiro and Itano, Toshifumi and Miyamoto, Osamu
Journal: Brain research (2013): 115--131
Involvement of thioredoxin-binding protein 2 in the antitumor activity of CD437
Authors: Matsuoka, Saori and Tsuchiya, Hiroyuki and Sakabe, Tomohiko and Watanabe, Yumi and Hoshikawa, Yoshiko and Kurimasa, Akihiro and Itamochi, Hiroaki and Harada, Tasuku and Terakawa, Naoki and Masutani, Hiroshi and others, undefined
Journal: Cancer science (2008): 2485--2490