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BAPTA, AM *UltraPure Grade* *CAS 126150-97-8*
BAPTA AM is cell-permeable version of BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), a cell-permeable calcium chelator. This BAPTA derivative is used for adjusting calcium concentrations in cells and tissues. BAPTA is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.
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Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of BAPTA, AM *UltraPure Grade* *CAS 126150-97-8* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 130.774 µL | 653.868 µL | 1.308 mL | 6.539 mL | 13.077 mL |
| 5 mM | 26.155 µL | 130.774 µL | 261.547 µL | 1.308 mL | 2.615 mL |
| 10 mM | 13.077 µL | 65.387 µL | 130.774 µL | 653.868 µL | 1.308 mL |
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Citations
View all 10 citations: Citation Explorer
Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier
Authors: Rudd, Justin C and Smits, Jos PH and Kuwong, Patrick T and Johnson, Rachel E and Monga, Louise MN and van Vlijmen-Willems, Ivonne MJJ and Porter, Greer L and Halloran, Peter O and Sharma, Kanika and Schmidt, Karina N and others,
Journal: Nature Communications (2025): 6892
Authors: Rudd, Justin C and Smits, Jos PH and Kuwong, Patrick T and Johnson, Rachel E and Monga, Louise MN and van Vlijmen-Willems, Ivonne MJJ and Porter, Greer L and Halloran, Peter O and Sharma, Kanika and Schmidt, Karina N and others,
Journal: Nature Communications (2025): 6892
Regulation of Calcium entry by cyclic GMP signaling in Toxoplasma gondii
Authors: Triana, Miryam A Hortua and M{\'a}rquez-Nogueras, Karla M and Fazli, Mojtaba Sedigh and Quinn, Shannon and Moreno, Silvia NJ
Journal: Journal of Biological Chemistry (2024): 105771
Authors: Triana, Miryam A Hortua and M{\'a}rquez-Nogueras, Karla M and Fazli, Mojtaba Sedigh and Quinn, Shannon and Moreno, Silvia NJ
Journal: Journal of Biological Chemistry (2024): 105771
Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload
Authors: Xiao, Juan and Feng, Xueping and Huang, Xiao-Ying and Huang, Zhongshi and Huang, Yanqiang and Li, Chaogan and Li, Genliang and Nong, Song and Wu, Ruoshi and Huang, Yongzhi and others, undefined
Journal: Molecular Medicine (2016): 643
Authors: Xiao, Juan and Feng, Xueping and Huang, Xiao-Ying and Huang, Zhongshi and Huang, Yanqiang and Li, Chaogan and Li, Genliang and Nong, Song and Wu, Ruoshi and Huang, Yongzhi and others, undefined
Journal: Molecular Medicine (2016): 643
Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells
Authors: Kameoka, Shoichiro and Kameyama, Takeshi and Hayashi, Takaya and Sato, Seiichi and Ohnishi, Naomi and Hayashi, Takeru and Murata-Kamiya, Naoko and Higashi, Hideaki and Hatakeyama, Masanori and Takaoka, Akinori
Journal: Biomedical Research (2016): 21--27
Authors: Kameoka, Shoichiro and Kameyama, Takeshi and Hayashi, Takaya and Sato, Seiichi and Ohnishi, Naomi and Hayashi, Takeru and Murata-Kamiya, Naoko and Higashi, Hideaki and Hatakeyama, Masanori and Takaoka, Akinori
Journal: Biomedical Research (2016): 21--27
Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels
Authors: Yang, Xinhui and Jiang, Jiangtao and Yang, Xinyan and Han, Jichun and Zheng, Qiusheng
Journal: Molecular medicine reports (2016): 911--919
Authors: Yang, Xinhui and Jiang, Jiangtao and Yang, Xinyan and Han, Jichun and Zheng, Qiusheng
Journal: Molecular medicine reports (2016): 911--919
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