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BAPTA Amine

BAPTA Amine is an excellent building block to introduce BAPTA calcium chelator into a biological molecule that contains a carbonyl group such as COOH or CHO. BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is a common calcium-specific chelator. The presence of four carboxylic acid functional groups makes BAPTA possibly binding two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions. It is commonly used to chelate Ca2+, similarly to EGTA.

References

View all 13 references: Citation Explorer
The impact of calcium assay change on a local adjusted calcium equation.
Authors: Davies, Sarah L and Hill, Charlotte and Bailey, Lisa M and Davison, Andrew S and Milan, Anna M
Journal: Annals of clinical biochemistry (2016): 292-4
Calciuria determined by new NM-BAPTA calcium assay is not free from magnesium interference.
Authors: Brunel, Valéry and Wils, Julien
Journal: Clinica chimica acta; international journal of clinical chemistry (2015): 113-4
Development and in vitro characterization of ratiometric and intensity-based fluorescent ion sensors.
Authors: Cooley, Laurel A and Martin, Vladimir V and Gee, Kyle R
Journal: Methods in molecular biology (Clifton, N.J.) (2013): 133-45
PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells.
Authors: Moody, Terry W and Di Florio, Alessia and Jensen, Robert T
Journal: Journal of molecular neuroscience : MN (2012): 660-6
Regulation of cytosolic phospholipase A2 (cPLA2alpha) and its association with cell proliferation in human lens epithelial cells.
Authors: Wang, Yin and Xing, Kui-Yi and Lou, Marjorie F
Journal: Investigative ophthalmology & visual science (2011): 8231-40
Page updated on May 19, 2025

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Catalog Number20420
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Physical properties

Molecular weight

633.53

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure