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BAPTA Maleimide
BAPTA Maleimide is an excellent building block to introduce BAPTA calcium chelator into a biological molecule that contains a thiol group such as antibodies, proteins, peptides and thiol-modified oligos. BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is a common calcium-specific chelator. The presence of four carboxylic acid functional groups makes BAPTA possibly binding two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions. BAPTA is commonly used to chelate Ca2+, similarly to EGTA.
References
View all 5 references: Citation Explorer
Photoreversible stretching of a BAPTA chelator marshalling Ca2+-binding in aqueous media.
Authors: Ducrot, Aurélien and Tron, Arnaud and Bofinger, Robin and Sanz Beguer, Ingrid and Pozzo, Jean-Luc and McClenaghan, Nathan D
Journal: Beilstein journal of organic chemistry (2019): 2801-2811
Authors: Ducrot, Aurélien and Tron, Arnaud and Bofinger, Robin and Sanz Beguer, Ingrid and Pozzo, Jean-Luc and McClenaghan, Nathan D
Journal: Beilstein journal of organic chemistry (2019): 2801-2811
Ca-NIR: a ratiometric near-infrared calcium probe based on a dihydroxanthene-hemicyanine fluorophore.
Authors: Collot, Mayeul and Ponsot, Flavien and Klymchenko, Andrey S
Journal: Chemical communications (Cambridge, England) (2017): 6117-6120
Authors: Collot, Mayeul and Ponsot, Flavien and Klymchenko, Andrey S
Journal: Chemical communications (Cambridge, England) (2017): 6117-6120
Protein-specific localization of a rhodamine-based calcium-sensor in living cells.
Authors: Best, Marcel and Porth, Isabel and Hauke, Sebastian and Braun, Felix and Herten, Dirk-Peter and Wombacher, Richard
Journal: Organic & biomolecular chemistry (2016): 5606-11
Authors: Best, Marcel and Porth, Isabel and Hauke, Sebastian and Braun, Felix and Herten, Dirk-Peter and Wombacher, Richard
Journal: Organic & biomolecular chemistry (2016): 5606-11
Water-soluble, redox-active organometallic calcium chelators.
Authors: Bhattacharyya, Koyel X and Boubekeur-Lecaque, Leïla and Tapsoba, Issa and Maisonhaute, Emmanuel and Schöllhorn, Bernd and Amatore, Christian
Journal: Dalton transactions (Cambridge, England : 2003) (2012): 14257-64
Authors: Bhattacharyya, Koyel X and Boubekeur-Lecaque, Leïla and Tapsoba, Issa and Maisonhaute, Emmanuel and Schöllhorn, Bernd and Amatore, Christian
Journal: Dalton transactions (Cambridge, England : 2003) (2012): 14257-64
Novel fluo-4 analogs for fluorescent calcium measurements.
Authors: Martin, Vladimir V and Beierlein, Michael and Morgan, Josh L and Rothe, Anca and Gee, Kyle R
Journal: Cell calcium (2004): 509-14
Authors: Martin, Vladimir V and Beierlein, Michael and Morgan, Josh L and Rothe, Anca and Gee, Kyle R
Journal: Cell calcium (2004): 509-14
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