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BAPTA, tetrasodium salt *CAS 126824-24-6*

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Physical properties
Molecular weight564.36
SolventWater
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200

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CAS
126824-24-6
Molecular weight
564.36
BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid) is a water-soluble and cell-impermeable calcium chelator. It has high selectivity to calcium. BAPTA is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.

Calculators


Common stock solution preparation

Table 1. Volume of Water needed to reconstitute specific mass of BAPTA, tetrasodium salt *CAS 126824-24-6* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM177.192 µL885.959 µL1.772 mL8.86 mL17.719 mL
5 mM35.438 µL177.192 µL354.384 µL1.772 mL3.544 mL
10 mM17.719 µL88.596 µL177.192 µL885.959 µL1.772 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Citations


View all 7 citations: Citation Explorer
Regulation of Calcium entry by cyclic GMP signaling in Toxoplasma gondii
Authors: Triana, Miryam A Hortua and M{\'a}rquez-Nogueras, Karla M and Fazli, Mojtaba Sedigh and Quinn, Shannon and Moreno, Silvia NJ
Journal: Journal of Biological Chemistry (2024): 105771
Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels
Authors: Yang, Xinhui and Jiang, Jiangtao and Yang, Xinyan and Han, Jichun and Zheng, Qiusheng
Journal: Molecular medicine reports (2016): 911--919
Helicobacter pylori induces IL-1&beta; protein through the inflammasome activation in differentiated macrophagic cells
Authors: Kameoka, Shoichiro and Kameyama, Takeshi and Hayashi, Takaya and Sato, Seiichi and Ohnishi, Naomi and Hayashi, Takeru and Murata-Kamiya, Naoko and Higashi, Hideaki and Hatakeyama, Masanori and Takaoka, Akinori
Journal: Biomedical Research (2016): 21--27
Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload
Authors: Xiao, Juan and Feng, Xueping and Huang, Xiao-Ying and Huang, Zhongshi and Huang, Yanqiang and Li, Chaogan and Li, Genliang and Nong, Song and Wu, Ruoshi and Huang, Yongzhi and others, undefined
Journal: Molecular Medicine (2016): 643
Ras guanyl nucleotide releasing protein 2 affects cell viability and cell--matrix adhesion in ECV304 endothelial cells
Authors: Takino, Junichi and Nagamine, Kentaro and Hori, Takamitsu
Journal: Cell adhesion &amp; migration (2013): 262--266
Delayed administration of the nucleic acid analog 2Cl-C. OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke
Authors: Okabe, Naohiko and Nakamura, Emi and Himi, Naoyuki and Narita, Kazuhiko and Tsukamoto, Ikuko and Maruyama, Tokumi and Sakakibara, Norikazu and Nakamura, Takehiro and Itano, Toshifumi and Miyamoto, Osamu
Journal: Brain research (2013): 115--131
Involvement of thioredoxin-binding protein 2 in the antitumor activity of CD437
Authors: Matsuoka, Saori and Tsuchiya, Hiroyuki and Sakabe, Tomohiko and Watanabe, Yumi and Hoshikawa, Yoshiko and Kurimasa, Akihiro and Itamochi, Hiroaki and Harada, Tasuku and Terakawa, Naoki and Masutani, Hiroshi and others, undefined
Journal: Cancer science (2008): 2485--2490