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BC-Maleimide
Ordering information
| Price | |
| Catalog Number | |
| Unit Size | |
| Quantity |
Additional ordering information
| Telephone | 1-800-990-8053 |
| Fax | 1-800-609-2943 |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Shipping | Standard overnight for United States, inquire for international |
Physical properties
| Solvent | DMSO |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
| Storage | Freeze (< -15 °C); Minimize light exposure |
| UNSPSC | 12171501 |
Alternative formats
| BC Succinimidyl Ester |
| Overview |  SDSProtocol |
CLIP-tag is a modified version of SNAP-tag. It is also a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. Instead of benzylguanine derivatives, CLIP tag is engineered to react with benzylcytosine derivatives. It can be used as a protein tag for tagging your protein of interest (POI). BC Maleimide is a thiol-reactive building block for preparing of SNAP substrates from thiol-containing labels or biological targets. BC Maleimide building block facilities the development of various CLIP-tag substrates for labeling CLIP-tag fusion proteins for a wide range of biological applications.
Images
Figure 1. Chemical structure for BC-Malaimide.
References
View all 27 references: Citation Explorer
Expanding the substrate selectivity of SNAP/CLIP-tagging of intracellular targets.
Authors: Macias-Contreras, Miguel and Little, Kevin N and Zhu, Lei
Journal: Methods in enzymology (2020): 233-257
Authors: Macias-Contreras, Miguel and Little, Kevin N and Zhu, Lei
Journal: Methods in enzymology (2020): 233-257
Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method.
Authors: Yugami, Masato and Okano, Hideyuki and Nakanishi, Atsushi and Yano, Masato
Journal: PloS one (2020): e0231450
Authors: Yugami, Masato and Okano, Hideyuki and Nakanishi, Atsushi and Yano, Masato
Journal: PloS one (2020): e0231450
Visualization of Spirochetes by Labeling Membrane Proteins With Fluorescent Biarsenical Dyes.
Authors: Hillman, Chadwick and Stewart, Philip E and Strnad, Martin and Stone, Hunter and Starr, Tregei and Carmody, Aaron and Evans, Tyler J and Carracoi, Valentina and Wachter, Jenny and Rosa, Patricia A
Journal: Frontiers in cellular and infection microbiology (2019): 287
Authors: Hillman, Chadwick and Stewart, Philip E and Strnad, Martin and Stone, Hunter and Starr, Tregei and Carmody, Aaron and Evans, Tyler J and Carracoi, Valentina and Wachter, Jenny and Rosa, Patricia A
Journal: Frontiers in cellular and infection microbiology (2019): 287
Quantifying transcription factor binding dynamics at the single-molecule level in live cells.
Authors: Presman, Diego M and Ball, David A and Paakinaho, Ville and Grimm, Jonathan B and Lavis, Luke D and Karpova, Tatiana S and Hager, Gordon L
Journal: Methods (San Diego, Calif.) (2017): 76-88
Authors: Presman, Diego M and Ball, David A and Paakinaho, Ville and Grimm, Jonathan B and Lavis, Luke D and Karpova, Tatiana S and Hager, Gordon L
Journal: Methods (San Diego, Calif.) (2017): 76-88
Rational Design and Applications of Semisynthetic Modular Biosensors: SNIFITs and LUCIDs.
Authors: Farrants, Helen and Hiblot, Julien and Griss, Rudolf and Johnsson, Kai
Journal: Methods in molecular biology (Clifton, N.J.) (2017): 101-117
Authors: Farrants, Helen and Hiblot, Julien and Griss, Rudolf and Johnsson, Kai
Journal: Methods in molecular biology (Clifton, N.J.) (2017): 101-117
mCarts: Genome-Wide Prediction of Clustered Sequence Motifs as Binding Sites for RNA-Binding Proteins.
Authors: Weyn-Vanhentenryck, Sebastien M and Zhang, Chaolin
Journal: Methods in molecular biology (Clifton, N.J.) (2016): 215-26
Authors: Weyn-Vanhentenryck, Sebastien M and Zhang, Chaolin
Journal: Methods in molecular biology (Clifton, N.J.) (2016): 215-26
A Fluorescent Reporter for Single Cell Analysis of Gene Expression in Clostridium difficile.
Authors: Cassona, Carolina Piçarra and Pereira, Fátima and Serrano, Mónica and Henriques, Adriano O
Journal: Methods in molecular biology (Clifton, N.J.) (2016): 69-90
Authors: Cassona, Carolina Piçarra and Pereira, Fátima and Serrano, Mónica and Henriques, Adriano O
Journal: Methods in molecular biology (Clifton, N.J.) (2016): 69-90
Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system.
Authors: Clifford, Rebecca J and Maryon, Edward B and Kaplan, Jack H
Journal: Journal of cell science (2016): 1711-21
Authors: Clifford, Rebecca J and Maryon, Edward B and Kaplan, Jack H
Journal: Journal of cell science (2016): 1711-21
A Monoclonal Antibody That Discriminates Between SNAP-Tagged and CLIP-Tagged Proteins.
Authors: Bialon, Magdalena and Grezella, Clara and Friesen, Ludmila and Sieben, Thorsten and Pham, Anh-Tuan and Fischer, Rainer and Barth, Stefan and Püttmann, Christiane and Stein, Christoph
Journal: Monoclonal antibodies in immunodiagnosis and immunotherapy (2016): 141-7
Authors: Bialon, Magdalena and Grezella, Clara and Friesen, Ludmila and Sieben, Thorsten and Pham, Anh-Tuan and Fischer, Rainer and Barth, Stefan and Püttmann, Christiane and Stein, Christoph
Journal: Monoclonal antibodies in immunodiagnosis and immunotherapy (2016): 141-7
Understanding FRET as a research tool for cellular studies.
Authors: Shrestha, Dilip and Jenei, Attila and Nagy, Péter and Vereb, György and Szöllősi, János
Journal: International journal of molecular sciences (2015): 6718-56
Authors: Shrestha, Dilip and Jenei, Attila and Nagy, Péter and Vereb, György and Szöllősi, János
Journal: International journal of molecular sciences (2015): 6718-56