Name: BC-Maleimide
Brand: AAT Bioquest
SKU: 12567
Price: 226 USD
Availability: InStock

BC-Maleimide

CLIP-tag is a modified version of SNAP-tag. It is also a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. Instead of benzylguanine derivatives, CLIP tag is engineered to react with benzylcytosine derivatives. It can be used as a protein tag for tagging your protein of interest (POI). BC Maleimide is a thiol-reactive building block for preparing of SNAP substrates from thiol-containing labels or biological targets. BC Maleimide building block facilities the development of various CLIP-tag substrates for labeling CLIP-tag fusion proteins for a wide range of biological applications.

Datasheet

SDS

COA

Catalog	Size	Price	Quantity
12567	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of BC-Maleimide to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	262.199 µL	1.311 mL	2.622 mL	13.11 mL	26.22 mL
5 mM	52.44 µL	262.199 µL	524.398 µL	2.622 mL	5.244 mL
10 mM	26.22 µL	131.099 µL	262.199 µL	1.311 mL	2.622 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	381.39 g/mol	=	mL	x	mM	=	mmol

References

View all 27 references: Citation Explorer

Expanding the substrate selectivity of SNAP/CLIP-tagging of intracellular targets.

Authors:

Macias-Contreras, Miguel and Little, Kevin N and Zhu, Lei

Journal:

Methods in enzymology (2020): 233-257

Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method.

Authors:

Yugami, Masato and Okano, Hideyuki and Nakanishi, Atsushi and Yano, Masato

Journal:

PloS one (2020): e0231450

Visualization of Spirochetes by Labeling Membrane Proteins With Fluorescent Biarsenical Dyes.

Authors:

Hillman, Chadwick and Stewart, Philip E and Strnad, Martin and Stone, Hunter and Starr, Tregei and Carmody, Aaron and Evans, Tyler J and Carracoi, Valentina and Wachter, Jenny and Rosa, Patricia A

Journal:

Frontiers in cellular and infection microbiology (2019): 287

Quantifying transcription factor binding dynamics at the single-molecule level in live cells.

Authors:

Presman, Diego M and Ball, David A and Paakinaho, Ville and Grimm, Jonathan B and Lavis, Luke D and Karpova, Tatiana S and Hager, Gordon L

Journal:

Methods (San Diego, Calif.) (2017): 76-88

Rational Design and Applications of Semisynthetic Modular Biosensors: SNIFITs and LUCIDs.

Authors:

Farrants, Helen and Hiblot, Julien and Griss, Rudolf and Johnsson, Kai

Journal:

Methods in molecular biology (Clifton, N.J.) (2017): 101-117

Physical properties

Molecular weight	381.39
Solvent	DMSO

Usage and storage

Intended use	Research Use Only (RUO)
Storage	Freeze (< -15 °C); Minimize light exposure

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Page updated on August 29, 2026